news, journals and articles from all over the world.
Molecular Designs, a leading provider of PCR assays, associated reagents and equipment, is excited to announce the acquisition of Lamda Biotech, a specialized provider of research products for application in molecular biology, functional genomics, proteomics and gene therapy.
NIH grant supports study of the spread of Huntington’s disease in the brain
Zhijian “James” Chen, Ph.D., Professor of Molecular Biology and Director of the Center for Inflammation Research at UT Southwestern Medical Center, has been awarded the Albert Lasker Basic Medical Research Award for his discovery of the cGAS enzyme.
Scientists are finding clues for how to treat diabetes and hormone disorders in an unexpected place: a toxin from one of the most venomous animals on the planet.
A research team has reviewed significant progress in understanding the growth and stress response mechanisms in bermudagrass, a widely distributed and valuable grass species.
Microscopy engineers at Washington University in St. Louis model how molecules move to enhance understanding of nanoscale biological systems.
ROCKVILLE, MD – Karen Fleming has been elected President-elect of the Biophysical Society (BPS). She will assume the office of President-elect at the 2025 Annual Meeting in Los Angeles, California and begin her term as President during the 2026 Annual Meeting in San Francisco, California. Fleming is a Professor of Biophysics at Johns Hopkins University.
Certest Biotec, is a Spanish an innovative and technology-based company founded in 2002 that has always relied on research and development of new products, as well as exploration of new market niches and opportunities, for its growth.
A team led by UT Southwestern Medical Center researchers has discovered a new way that cells regulate senescence, an irreversible end to cell division.
Two genes working in tandem play a critical role in shaping the identity and behavior of prostate cancer cells and their response to treatment, UT Southwestern Medical Center researchers report.
Working under the umbrella of the PsychENCODE Consortium, the mental health research project established in 2015 by the National Institutes of Health, a team of Mount Sinai scientists has uncovered important new insights into the molecular biology of neuropsychiatric disease through two new studies published in a special issue of Science on Friday, May 24.
By examining which genes were turned on and off in a mix of cell types from breast cancer biopsies, a team led by UT Southwestern Medical Center researchers developed a tool that can accurately predict which patients with breast cancer will respond to immunotherapies.
A gene therapy developed by researchers at UT Southwestern Medical Center for a rare disease called giant axonal neuropathy (GAN) was well tolerated in pediatric patients and showed clear benefits, a new study reports. Findings from the phase one clinical trial, published in the New England Journal of Medicine, could offer hope for patients with this rare condition and a host of other neurological diseases.
A nanoparticle-based therapy developed by UT Southwestern Medical Center scientists stimulated an immune pathway that eradicated tumors in mouse models of various cancer types. Their findings, published in Science Immunology, offer a new way to potentially harness the power of the body’s immune system against cancer.
In October 2023, the Advanced Photon Source (APS), a U.S. Department of Energy (DOE) Office of Science user facility at DOE’s Argonne National Laboratory, officially launched a new initiative to expand biological and environmental research at the world leading X-ray and analysis facility.
Broccoli sprouts have been discovered to contain seven times more polysulfides than mature broccoli
With daylight savings time ending soon, we anticipate a change in the timing of daylight hours with the sunrise occurring earlier in the morning.
Scientists revealed the intercellular choreography that governs protein regulation, including how unwanted proteins are tagged for degradation, an important player in human health and disease.
Zhijian “James” Chen, Ph.D., Professor of Molecular Biology at UT Southwestern Medical Center, has been awarded the 2023 Louisa Gross Horwitz Prize in recognition of his groundbreaking work on innate immunity.
Experts in cell signalling at the Babraham Institute have identified how prostate cancer cells achieve cell growth free from the usual growth cues and regulators.
Researchers at UT Southwestern Medical Center have discovered an intracellular mechanism that converts protective intestinal cells into disease-driving pathogenic cells, a finding that could lead to improved treatments for patients with inflammatory bowel disease (IBD).
According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd—but very important—to help them fight pathogens and destroy cancer cells.
UC San Diego scientists debut Greengenes2, a massive reference database that could be used to reconcile years of microbiome studies.
A set of nine scientific papers was released today in the Nature family of journals and the journal Cell Reports describing breakthroughs in creating an open framework for scientists to map the individual cells of the human body in two and three dimensions.
Researchers from SANKEN (The Institute of Scientific and Industrial Research) and the Graduate School of Frontier Biosciences at Osaka University reported the development of a sensor to look at Pcdh interactions in live neurons, which brings us closer to understanding this mystery.
The entire biosynthetic pathway of actinopyridazone has been unveiled, revealing that an unprecedented carrier protein-mediated ring-forming step is key to its synthesis.
A consortium of government, industry, and nonprofit partners will fund gene therapy clinical trials for three different rare diseases at UT Southwestern Medical Center and Children’s Health, where scientists are working on gene therapies to treat neurodevelopmental disorders in children.
Influenza A is one of two influenza viruses that fuel costly annual flu seasons and is a near constant threat to humans and many other animals. It’s also responsible for occasional pandemics that, like the one in 1918, leave millions dead and wreak havoc on health systems and wider society. Influenza A was first identified as a health threat nearly a century ago, but only in the last decade have scientists identified one of the virus’s key proteins for infiltrating host cells and short-circuiting their defenses.
A consortium of government, industry, and nonprofit partners will fund gene therapy clinical trials for three rare diseases at UT Southwestern Medical Center, where scientists are working on gene therapies to treat neurodevelopmental disorders in children.
Japanese biochemist and molecular biologist Noboru Mizushima, M.D., Ph.D., has been named the inaugural recipient of the Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern Medical Center. Dr. Mizushima is an internationally recognized scientist who has made significant strides in unraveling the complex processes of mammalian autophagy, a fundamental cellular mechanism responsible for maintaining cellular health and functionality.
Working with live squid hatchlings at Scripps Institution of Oceanography, UC San Diego scientists find the animals can tune their proteome on the fly in response to changes in ocean temperature via the unique process of RNA recoding. The findings inspire new questions about basic protein function.
ASBMB travel awards support biomedical research projects and career development for trainees from Argentina, Chile, Mexico, Uruguay and Spain to work in labs in North America
UC San Diego scientists develop an interactive software that enables scientists to better investigate the DNA damage response.
Researchers from the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), the Cluster of Excellence Physics of Life (PoL) and the Biotechnology Center (BIOTEC) of the TU Dresden in Dresden, Germany, and the National Centre for Biological Sciences (NCBS) in Bangalore, India, discovered a novel molecular system that uses an alternative chemical energy and employs a novel mechanism to perform mechanical work.
UT Southwestern Medical Center stem cell and developmental biologists and colleagues have developed a method to produce bovine blastoids, a crucial step in replicating embryo formation in the lab that could lead to the development of new reproductive technologies for cattle breeding.
In the cell nucleus, numerous proteins bind to the DNA molecule in order to regulate the activity of certain genes. One such is the TATA-box binding protein (TBP), which binds to a specific DNA sequence and constitutes an initial signal for the reading of DNA.
In testimony to federal appropriators, the ASBMB argues a big boost for NIGMS is long overdue and calls for a 10% increase
UC San Diego researchers find stem cells use a surprising system for discarding misfolded proteins. This unique pathway could be the key to maintaining long-term health and preventing age-related blood and immune disorders.
A group of researchers have used the Advanced Photon Source to look at monoclonal antibodies to subvert the “shield” of the Lassa virus, potentially paving the way for new therapies.
UT Southwestern Medical Center researchers have mapped gene control elements in specialized cardiac cells responsible for coordinating heartbeats. The findings of the genome exploration study, published in The Journal of Clinical Investigation, provide insight into how heartbeats are regulated and could impact diagnosis and risk prediction for a variety of common arrhythmias.
UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery. The findings, reported in Cell, could lead to new ways of controlling gene regulation and may one day lead to new treatments for a broad array of diseases.
UT Southwestern physician-scientist Hesham Sadek, M.D., Ph.D., has received the prestigious National Institutes of Health (NIH) Outstanding Investigator Award to support his ongoing research into mechanisms behind heart regeneration that could lead to treatments for heart failure.
Two of UT Southwestern’s Howard Hughes Medical Institute researchers in biochemistry and molecular biology will lead separate teams as part of HHMI’s Emerging Pathogens Initiative (EPI) targeting infectious diseases that pose a threat to human health.
Editing a gene that prompts a cascade of damage after a heart attack appeared to reverse this inevitable course in mice, leaving their hearts remarkably unharmed, a new study by UT Southwestern scientists showed. The findings, published in Science, could lead to a new strategy for protecting patients from the consequences of heart disease.
UC San Diego scientists discover a molecular pathway critical to the initiation of pancreatic tumors. The findings may inspire new chemotherapeutic drugs targeting early stages of tumor formation and spread.
Models based on an average cell are useful, but they may not accurately describe how individual cells really work. New possibilities opened up with the advent of single-cell live imaging technologies. Now it is possible to peer into the lives of individual cells. In a new paper in PLOS Genetics, a team of biologists and physicists from Washington University in St. Louis and Purdue University used actual single-cell data to create an updated framework for understanding the relationship between cell growth, DNA replication and division in a bacterial system.
UC San Diego study reveals critical insights into the complex biology of tissue-specific T cells, paving the way for a new branch of precision therapeutics in immunity, autoimmunity, and cancer.
For the first time, researchers at UC San Diego have shown that changes in gene expression happen almost entirely during the transcription stage while the cells are growing. The researchers have provided a simple quantitative formula linking regulatory control to mRNA and protein levels.
Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease.
UC San Diego scientists identify a new molecular model and potential therapeutic target for gout, the most common form of inflammatory arthritis.
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