New drug targets early instigator of Alzheimer’s disease

Over a hundred years after they were first identified, two ominous signposts of Alzheimer’s disease (AD) remain central topics of research–both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies into senile plaques, which congregate in the…

Findings shed new light on why Zika causes birth defects in some pregnancies

One thing is clear when it comes to Zika: pregnant women must do everything they can to avoid getting infected. If the virus gains entry to the mother’s cells, it can also infect the baby and cause severe birth defects,…

New proteomics technique gives insights into ubiquitin signalling

Australian researchers are among the first in the world to have access to a new approach to understand intricate changes that control how proteins function in our cells in health and disease. The new proteomics technique called ‘ubiquitin clipping’ allows…

Adding MS Drug to Targeted Cancer Therapy May Improve Glioblastoma Outcomes

The multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice by reaching stem cells at the tumor’s root, according to a new UC San Diego School of Medicine study published in Science Translational Medicine.