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UrduUAB’s Undergraduate Immunology Program, one of a handful of immunology majors available in the United States, gives students real lab experience with more than 100 faculty pursuing cutting-edge research.The entire planet, more or less, is fixated on the greatest pandemic in modern memory. Claire Elliott is already preparing for the next one.
Tag: Immune System
‘Chaperone’ Protein Protection From Autoimmune Diseases in Mice Suggests Same For Humans
Like a parent of teenagers at a party, Mother Nature depends on chaperones to keep one of her charges, the immune system, in line so that it doesn’t mistakenly attack normal cells, tissues and organs in our bodies. A recent study by Johns Hopkins Medicine researchers has demonstrated that in mice — and probably humans as well — one biological chaperone may play a key role in protection from such attacks, known as autoimmune responses, which are a hallmark of diseases such as multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus and type 1 diabetes.
Moffitt Researchers Identify Molecular Pathway That Controls Immunosuppression in Tumors
In a new article published in the journal Immunity, Moffitt Cancer Center researchers reveas how protein-signaling pathways associated with cellular stress processes turn myeloid cells into tumor-promoting players. They also suggest that targeting the PERK protein may be an effective therapeutic approach to reactivate the immune system and boost the effectiveness of immunotherapy.
Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells
Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new UW–Madison study shows.
Learning from the Recovered
Researchers at Harvard Medical School and at Brigham and Women’s Hospital are adapting an antibody-detection tool to study the aftermath of infections by the novel coronavirus that is causing the current global pandemic.
Rutgers Expert Available to Discuss Physical Activity and Health During COVID-19 Crisis
New Brunswick, N.J. (March 18, 2020) – Rutgers University–New Brunswick Professor Brandon L. Alderman is available for interviews on how to stay active when gyms are closed and you’re confined to home during the COVID-19 crisis. Alderman can also discuss…
Mimicking Cancer’s Evasive Tactics, Microparticles Show Promise Against Transplant Rejection
Inspired by a tactic cancer cells use to evade the immune system, University of Pittsburgh researchers have engineered tiny particles that can trick the body into accepting transplanted tissue as its own, while leaving the immune system intact.
Activating immune cells could revitalize the aging brain, study suggests
Researchers at Albany Medical College in New York have discovered that a specific type of immune cell accumulates in older brains, and that activating these cells improves the memory of aged mice. The study, which will be published February 5 in the Journal of Experimental Medicine (JEM), suggests that targeting these cells might reduce age-related cognitive decline and combat aging-associated neurodegenerative disease in humans.
Targeting the cancer microenvironment
The recognition of bacterial infections or foreign substances is mediated and controlled by the human immune system. This innate and adaptive immune system comprises the most important metabolic and cellulare processes to fight against infections and other diseases.
Russian expert is ready to comment on the coronavirus
Pavel Volchkov heads the Genome Engineering Lab at the Moscow Institute of Physics and Technology (MIPT), that has several key projects, all of them involving genome editing mediated by the CRISPR/Cas technology. Discovered just a few years ago, CRISPR/Cas has…
Finding a new way to fight late-stage sepsis
Researchers have developed a way to prop up a struggling immune system to enable its fight against sepsis, a deadly condition resulting from the body’s extreme reaction to infection.
Father’s X chromosome may yield clues to higher rates of autoimmune disease in women
UCLA scientists have discovered one reason why autoimmune diseases are more prevalent in women than in men.
Peanut allergy vaccine to rewrite the immune system
Peanut allergies could become a thing of the past as breakthrough research from the University of South Australia develops a radically novel vaccination that’s poised to cure the potentially life threatening condition.
Early immune response may improve cancer immunotherapies
In a paper published in the Journal of Biological Chemistry, University of Illinois at Chicago researchers and colleagues report a new mechanism for detecting foreign material during early immune responses.
HIV: Overwhelming the enemy from the start
Virologist Eric Cohen and his team have identified a way to thwart HIV infection at its very early stages.
E-cigarettes Boost Infection Risk by Blocking Action of Immune Cells
A new study finds that e-cigarette vapor weakens the mobility and function of immune cells designed to fight infection. This reduced ability may increase the risk of bacterial illnesses in people who vape. The research is published ahead of print in the American Journal of Physiology—Cell Physiology.
Moffitt Researchers Identify a Mechanism Controlling Tumor Cell Recognition by Immune Cells
Immunotherapy has become a standard treatment approach for several types of cancer, including melanoma. However, tumors can escape immune cell detection even with the use of immunotherapies. In a new study published in Cancer Immunology Research, Moffitt Cancer Center researchers, in collaboration with the University of Miami’s Miller School of Medicine, describe a cellular mechanism that controls tumor cell recognition by immune cells.
Study fingers new player in cancer immunity
Study in mice reveals new immune regulatory mechanism involved in cancer, viral infections
Silencing immune-regulating gene in immune cells eradicated colon cancer in mice
Approach also helped some animals clear an aggressive form of melanoma
Findings offer pathway for design of new class of immune-based cancer therapies
When studying immune cells, environment matters
GRAND RAPIDS, Mich. (Oct. 10, 2019) — For years, scientists have used cells grown in petri dishes to study the metabolic processes that fuel the immune system. But a new report in Immunity suggests looking outside the dish and into living organisms gives a drastically different view of the way immune cells process and use energy.
IU School of Medicine awarded $36 million NIH grant for Alzheimer’s disease drug discovery center
The IU-led center is one of only two multi-institution teams in the nation selected as part of a new federal program intended to improve, diversify and reinvigorate the Alzheimer’s disease drug development pipeline.
Engineered killer T cells could provide long-lasting immunity against cancer
In experiments with mice, UCLA researchers have shown they can harness the power of iNKT cells to attack tumor cells and treat cancer. The new method, described in the journal Cell Stem Cell, suppressed the growth of multiple types of human tumors that had been transplanted into the animals.
Moderate to Heavy Drinking During Pregnancy Alters Genes in Newborns, Mothers
Mothers who drink moderate to high levels of alcohol during pregnancy may be changing their babies’ DNA, according to a Rutgers-led study.