Inspired by kirigami, the Japanese art of folding and cutting paper to create three-dimensional structures, MIT engineers and their collaborators have designed a new type of stent that could be used to deliver drugs to the gastrointestinal tract, respiratory tract, or other tubular organs in the body.
Category: Research Results
UIC research identifies potential pathways to treating alcohol use disorder, depression
A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression. The study, “Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure,” is published in the journal Translational Psychiatry by researchers at UIC’s Center for Alcohol Research in Epigenetics.
Plant-based diet protects from hypertension, preeclampsia
A plant-based diet appears to afford significant protection to rats bred to become hypertensive on a high-salt diet, scientists report. When the rats become pregnant, the whole grain diet also protects the mothers and their offspring from deadly preeclampsia.
Scientists discover how oxygen loss saps a lithium-ion battery’s voltage
SLAC and Stanford scientists took a unique and detailed nanoscale look at how oxygen seeps out of lithium-ion battery electrodes, sapping their energy over time. The results could suggest a fix.
New tissue-closure model may aid in promotion of faster wound healing
The observation of a previously undetected biological mechanism for closing gaps in living tissue improves basic understanding of the wound-healing process and may one day inform strategies to speed healing after surgery and could hold other medical benefits, according to a team of Penn State and Singapore researchers.
Defending Science And The First Amendment, ASA Asks Federal Judge To Dismiss Pacira’s Lawsuit
The American Society of Anesthesiologists (ASA) asked United States District Judge Madeline Cox Arleo on June 11 to see the “trade libel” suit filed by Pacira BioSciences two months ago for what it is: an egregious and unjustified public relations campaign that seeks to chill scientific research and debate about Pacira’s controversial drug EXPAREL (liposomal bupivacaine). In its case, Pacira disputes the conclusions of peer-reviewed articles and an editorial in the February 2021 issue of Anesthesiology that EXPAREL lacks a comparative benefit over standard bupivacaine, even though it costs 100 times as much.
Study Finds Dosing Strategy May Affect Immunotherapy Outcomes
DALLAS – June 14, 2021 – Overweight cancer patients receiving immunotherapy treatments live more than twice as long as lighter patients, but only when dosing is weight-based, according to a study by cancer researchers at UT Southwestern Medical Center.
Making a meal of DNA in the seafloor
While best known as the code for genetic information, DNA is also a nutrient for specialised microbes. An international team of researchers led by Kenneth Wasmund and Alexander Loy from the University of Vienna has discovered several bacteria in sediment samples from the Atlantic Ocean that use DNA as a food source.
New Combination of Materials Provides Progress Toward Quantum Computing
In research published today in Nature Communications, engineers from Rensselaer Polytechnic Institute demonstrated how, when the TMDC materials they make are stacked in a particular geometry, the interaction that occurs between particles gives researchers more control over the devices’ properties. Specifically, the interaction between electrons becomes so strong that they form a new structure known as a correlated insulating state. This is an important step, researchers said, toward developing quantum emitters needed for future quantum simulation and computing.
People with Health Insurance Vaccinated More Than Those Without, Survey Finds
People with health insurance are receiving the COVID-19 vaccine at a higher rate than those without insurance, despite the vaccine being free, according to a national survey from the Edward J. Bloustein School of Planning and Public Policy at Rutgers University-New Brunswick.
Shrinking to survive: Bacteria adapt to a lifestyle in flux
Summer picnics and barbecues are only a few weeks away! As excited as you are to indulge this summer, Escherichia coli bacteria are eager to feast on the all-you-can-eat buffet they are about to experience in your gut. However, something unexpected will occur as E. coli cells end their journey through your digestive tract. Without warning, they will find themselves swimming in your toilet bowl, clinging to the last bits of nutrients attached to their bodies.
Study Links COVID-19 Public Health Efforts to Dramatic Drop in COPD Hospitalizations
Public health measures designed to reduce the spread of the COVID-19 virus may have fostered a substantial side benefit: A 53 percent drop in hospital admissions for chronic obstructive pulmonary disease (COPD), likely due to a drop in circulating seasonal respiratory viruses such as influenza.
The human ear detects half a millisecond delay in sound
Acoustics researchers at Aalto University, in collaboration with professional monitoring loudspeaker manufacturer Genelec, have investigated just how small of a variation in sound delay the human ear can detect in the most sensitive frequency range for hearing. People normally hear sound in the range of 20 and 20,000 hertz.
Trees, plants and soil could help cities cut their carbon footprints — when used smartly
Carbon footprint declarations are used in construction to ease product selection for low carbon building, but these standards don’t yet exist for green elements like soil, bushes and plants. A new study led by Aalto University is the first to map out how green infrastructure can be a resource for cities on the path to carbon neutrality.
Boundary of heliosphere mapped for the first time
For the first time, the boundary of the heliosphere has been mapped, giving scientists a better understanding of how solar and interstellar winds interact.
New Discovery Shows Human Cells can Write RNA sequences into DNA
In a discovery that challenges long-held dogma in biology, researchers show that mammalian cells can convert RNA sequences back into DNA, a feat more common in viruses than eukaryotic cells.
Physical activity may curb health care worker burnout
More physical activity programming could mitigate the effects of stress and improve worker mental and emotional health.
A ‘Nudge’ May Not Be Enough to Counter Fake News Online
Can people learn to better identify fake news about COVID-19—and if so, would they be less likely to share that fake story with others? Perhaps, but it may take more than simply priming them to think more critically beforehand.
Improving dialysis through design
Faculty from the McKelvey School of Engineering and the School of Medicine teamed up to design better grafts for dialysis patients.
Swiss-cheese design could help scientists harness the power of the sun
The big holes in Swiss cheese help make it a tasty treat. Now, scientists at PPPL are adding tiny, Swiss-cheese-type holes to components to improve the process of bringing to Earth the fusion energy that powers the sun and stars.
Financial toxicity associated with cancer care impacts nearly 50% of women with gynecologic cancer
Researchers report on how a diverse cohort of gynecologic cancer patients are affected by financial distress, also called “financial toxicity” in acknowledgment of the health hazards it can pose, in the International Journal of Gynecological Cancer.
Researchers discover a key cause of energy loss in spintronic materials
A study led by University of Minnesota Twin Cities researchers uncovered a property of magnetic materials that will allow engineers to develop more efficient spintronic devices in the future. Spintronics focuses on using the magnetic “spin” property of electrons instead of their charge, which improves the speed and efficiency of devices used for computing and data storage.
Study finds brain areas involved in seeking information about bad possibilities
Researchers at Washington University School of Medicine in St. Louis have identified the brain regions involved in choosing whether to find out if a bad event is about to happen.
AI Predicts How Patients with Viral Infections, Including COVID-19, Will Fare
UC San Diego School of Medicine researchers discovered gene expression patterns associated with pandemic viral infections, providing a map to help define patients’ immune responses, measure disease severity, predict outcomes and test therapies — for current and future pandemics.
NUS engineers devise novel approach to wirelessly power multiple wearable devices using a single source
Researchers from NUS have come up with a way to use one single device – such as a mobile phone or smart watch – to wirelessly power up to 10 wearables on a user. This novel method uses the human body as a medium for transmitting power. Their system can also harvest unused energy from electronics in a typical home or office environment to power the wearables.
Olfactory virtual realities show promise for mental health practices and integrative care
Study shows that scent-enhanced virtual reality technologies, or OVR, can be a safe and effective integrative approach to target anxiety, stress, and pain when combined with standard inpatient psychiatric care.
New Study Finds Weight-Loss Surgery Less Commonly Used in States with Highest Rates of Obesity
A new study released today finds residents in several states with the highest obesity rates in the country are among the least likely to undergo weight-loss surgery, long considered the standard of care for severe obesity and related diseases including type 2 diabetes and heart disease.
New Study Finds Weight-Loss Surgery Beneficial to Those with Mild to Moderate Obesity
Weight-loss surgery improves or resolves diseases including type 2 diabetes, heart disease and high blood pressure and can lead to significant and durable weight loss for many people, but the operation has largely been restricted to those with severe obesity, which means about 75 to 100 pounds overweight or a body mass index (BMI) of 35 or higher with an obesity-related disease.
Black and White Women Have Same Mutations Linked to Breast Cancer Risk
The prevalence of genetic mutations associated with breast cancer in Black and white women is the same.
Senolíticos reducen síntomas de COVID-19 en estudios preclínicos
Los investigadores de Mayo Clinic y sus colegas de la Universidad de Minnesota demostraron que la COVID-19 exacerba las consecuencias nocivas de las células senescentes en el cuerpo. En estudios preclínicos, los fármacos senolíticos descubiertos en Mayo redujeron considerablemente la inflamación, la enfermedad y la mortalidad debida a la infección por covid en ratones ancianos. Los resultados se publican en la revista Science.
Senolíticos reduzem os sintomas de COVID-19 em estudos pré-clínicos
Os pesquisadores da Mayo Clinic e colegas da Universidade de Minnesota mostraram que o COVID-19 intensifica o impacto prejudicial das células senescentes no corpo. Em estudos pré-clínicos, os medicamentos senolíticos descobertos na Mayo reduziram significativamente a inflamação, a gravidade da doença e a mortalidade da infecção por COVID em camundongos mais velhos. Essas conclusões foram publicadas na revista Science.
الأدوية المحللة للشيخوخة تقلل من أعراض فيروس كورونا المستجد (كوفيد-19) في الدراسات ما قبل السريرية
أظهر باحثو مايو كلينك وزملاؤهم في جامعة مينيسوتا أن فيروس كورونا المستجد (كوفيد-19) يفاقم التأثير الضار للخلايا الشائخة في الجسم. ففي الدراسات ما قبل السريرية، قللت الأدوية المحللة لالشيخوخة التي تم اكتشافها في مايو بشكل كبير من الالتهاب والمرض والوفيات الناجمة عن عَدوى فيروس كورونا المستجد في الفئران الأكبر سنًا. النتائج منشورة في مجلة ساينس.
Study Examines the Effects of COVID-19 on Human Kidney Cells
• The virus that causes COVID-19 can infect and replicate in human kidney cells, but this does not typically lead to cell death.
• Kidney cells that already have features of injury may be more easily infected and develop additional injury.
抗衰老药物在临床前研究中减少COVID-19症状。
妙佑医疗国际(Mayo Clinic)的研究人员和明尼苏达大学的同事表明,COVID-19(2019冠状病毒病)加剧了体内衰老细胞的破坏性影响。在临床前研究中,妙佑医疗国际研发的抗衰老药物显著降低了老年实验鼠因COVID(冠状病毒病)感染引起的炎症、疾病和死亡率。该研究结果已发表在《科学》期刊中。
How does COVID-19 affect patients with cancer? Largest U.S. study shares first results
New findings include a significant increase in risk of death among patients who had recently had chemotherapy.
Study Identifies How COVID-19 Linked to Alzheimer’s Disease-like Cognitive Impairment
A new Cleveland Clinic-led study has identified mechanisms by which COVID-19 can lead to Alzheimer’s disease-like dementia. The findings, published in Alzheimer’s Research & Therapy, indicate an overlap between COVID-19 and brain changes common in Alzheimer’s, and may help inform risk management and therapeutic strategies for COVID-19-associated cognitive impairment.
Study sheds light on treatment options for devastating childhood brain cancer
A new study led by Washington University School of Medicine in St. Louis provides new guidance on the treatment of medulloblastoma, a pediatric brain cancer. Some aspects of radiation therapy may be reduced while still providing effective treatment.
‘Disagreeable’ married men who shirk domestic responsibilities earn more at work, study shows
New research from the University of Notre Dame shows that “disagreeable” men in opposite-sex marriages are less helpful with domestic work, allowing them to devote greater resources to their jobs, which results in higher pay.
Novel liquid crystal metalens offers electric zoom
Researchers from Cornell University’s School of Applied and Engineering Physics and Samsung’s Advanced Institute of Technology have created a first-of-its-kind metalens – a metamaterial lens – that can be focused using voltage instead of mechanically moving its components.
A Spatiotemporal Symphony of Light
Using an ultrafast transmission electron microscope, researchers from the Technion – Israel Institute of Technology have, for the first time, recorded the propagation of combined sound and light waves in atomically thin materials.
Astronomy Meets Pathology to Identify Predictive Biomarkers for Cancer Immunotherapy
Pairing sky-mapping algorithms with advanced immunofluorescence imaging of cancer biopsies, researchers at The Mark Foundation Center for Advanced Genomics and Imaging at Johns Hopkins University and the Bloomberg~Kimmel Institute for Cancer Immunotherapy developed a robust platform to guide immunotherapy by predicting which cancers will respond to specific therapies targeting the immune system.
Cause, scope determined for deadly winter debris flow in Uttarakhand, India
The Uttarakhand region of India experienced a humanitarian tragedy on Feb. 7, 2021, when a wall of debris and water barreled down the Ronti Gad, Rishiganga and Dhauliganga river valleys. This debris flow destroyed two hydropower facilities and left more than 200 people dead or missing. A self-organized coalition of 53 scientists, including researchers from the University of Washington, came together in the days following the disaster to investigate the cause, scope and impacts.
No Clear Evidence Low-Calorie Sweeteners Harm Gut Microbiome but More Studies Warranted
New paper explores links among the diet, gut microbiota and health status.
Printing Flexible Wearable Electronics for Smart Device Applications
With the increase in demand for flexible wearable electronics, researchers have explored flexible energy storage devices, such as flexible supercapacitators, that are lightweight and safe and easily integrate with other devices. Printing electronics has proved to be an economical, simple, and scalable strategy for fabricating FSCs. In Applied Physics Reviews, researchers provide a review of printed FSCs in terms of ability to formulate functional inks, design printable electrodes, and integrate functions with other electronic devices.
COVID-19 Creates Hearing, Balance Disorders, Aggravates Tinnitus Symptoms
Evidence suggests auditory and vestibular effects should be added to the growing list of physiological impacts of COVID-19. During the 180th Meeting, Colleen Le Prell from the University of Texas at Dallas will talk about hearing and balance disorders associated with coronavirus infection and how pandemic-related stress and anxiety may aggravate tinnitus symptoms. Her presentation, “Hearing disorders secondary to infection with SARS-CoV-2,” will take place Thursday, June 10.
The survivability of animal species depends on the number of offspring
Researchers from Tel Aviv University took part in a new international study proposing an amendment to the widely accepted theory on the extinction of animal species – by moving the focus from the animal’s body size to its reproductive capacity.
Improved climate resilience through better seasonal forecasts
Lack of water, floods, or crop losses: As a result of climate change, pronounced periods of drought and rainfall are occurring more frequently and more intensively all around the world, causing human suffering and major economic damage.
CHIME telescope and collaborative efforts from WVU lead to the detection of more than 500 fast radio bursts
With the help of the radio telescope located at the Dominion Radio Astrophysical Observatory, operated by the National Research Council of Canada, in British Columbia, Canada, the telescope has nearly quadrupled the number of FRB discovered to date.
Study shows when people with cerebral palsy are most likely to break bones
Researchers at Michigan Medicine found people with cerebral palsy have fragile bones that present high fracture risk, but at different times across the lifespan compared to the general population. The results helped them develop new sex-specific critical periods of bone health for this population.
Researchers’ algorithm to make CRISPR gene editing more precise
It eventually became a Nobel prize-winning revolution when researchers first engineered CRISPR as a gene editing technology for bacterial, plant, animal and human cells.