UIC research identifies potential pathways to treating alcohol use disorder, depression

A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression. The study, “Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure,” is published in the journal Translational Psychiatry by researchers at UIC’s Center for Alcohol Research in Epigenetics.

Defending Science And The First Amendment, ASA Asks Federal Judge To Dismiss Pacira’s Lawsuit

The American Society of Anesthesiologists (ASA) asked United States District Judge Madeline Cox Arleo on June 11 to see the “trade libel” suit filed by Pacira BioSciences two months ago for what it is: an egregious and unjustified public relations campaign that seeks to chill scientific research and debate about Pacira’s controversial drug EXPAREL (liposomal bupivacaine). In its case, Pacira disputes the conclusions of peer-reviewed articles and an editorial in the February 2021 issue of Anesthesiology that EXPAREL lacks a comparative benefit over standard bupivacaine, even though it costs 100 times as much.

New Combination of Materials Provides Progress Toward Quantum Computing

In research published today in Nature Communications, engineers from Rensselaer Polytechnic Institute demonstrated how, when the TMDC materials they make are stacked in a particular geometry, the interaction that occurs between particles gives researchers more control over the devices’ properties. Specifically, the interaction between electrons becomes so strong that they form a new structure known as a correlated insulating state. This is an important step, researchers said, toward developing quantum emitters needed for future quantum simulation and computing.

Shrinking to survive: Bacteria adapt to a lifestyle in flux

Summer picnics and barbecues are only a few weeks away! As excited as you are to indulge this summer, Escherichia coli bacteria are eager to feast on the all-you-can-eat buffet they are about to experience in your gut. However, something unexpected will occur as E. coli cells end their journey through your digestive tract. Without warning, they will find themselves swimming in your toilet bowl, clinging to the last bits of nutrients attached to their bodies.

Study Links COVID-19 Public Health Efforts to Dramatic Drop in COPD Hospitalizations

Public health measures designed to reduce the spread of the COVID-19 virus may have fostered a substantial side benefit: A 53 percent drop in hospital admissions for chronic obstructive pulmonary disease (COPD), likely due to a drop in circulating seasonal respiratory viruses such as influenza.

Trees, plants and soil could help cities cut their carbon footprints — when used smartly

Carbon footprint declarations are used in construction to ease product selection for low carbon building, but these standards don’t yet exist for green elements like soil, bushes and plants. A new study led by Aalto University is the first to map out how green infrastructure can be a resource for cities on the path to carbon neutrality.

AI Predicts How Patients with Viral Infections, Including COVID-19, Will Fare

UC San Diego School of Medicine researchers discovered gene expression patterns associated with pandemic viral infections, providing a map to help define patients’ immune responses, measure disease severity, predict outcomes and test therapies — for current and future pandemics.

NUS engineers devise novel approach to wirelessly power multiple wearable devices using a single source

Researchers from NUS have come up with a way to use one single device – such as a mobile phone or smart watch – to wirelessly power up to 10 wearables on a user. This novel method uses the human body as a medium for transmitting power. Their system can also harvest unused energy from electronics in a typical home or office environment to power the wearables.

New Study Finds Weight-Loss Surgery Beneficial to Those with Mild to Moderate Obesity

Weight-loss surgery improves or resolves diseases including type 2 diabetes, heart disease and high blood pressure and can lead to significant and durable weight loss for many people, but the operation has largely been restricted to those with severe obesity, which means about 75 to 100 pounds overweight or a body mass index (BMI) of 35 or higher with an obesity-related disease.

Senolíticos reducen síntomas de COVID-19 en estudios preclínicos

Los investigadores de Mayo Clinic y sus colegas de la Universidad de Minnesota demostraron que la COVID-19 exacerba las consecuencias nocivas de las células senescentes en el cuerpo. En estudios preclínicos, los fármacos senolíticos descubiertos en Mayo redujeron considerablemente la inflamación, la enfermedad y la mortalidad debida a la infección por covid en ratones ancianos. Los resultados se publican en la revista Science.

Senolíticos reduzem os sintomas de COVID-19 em estudos pré-clínicos

Os pesquisadores da Mayo Clinic e colegas da Universidade de Minnesota mostraram que o COVID-19 intensifica o impacto prejudicial das células senescentes no corpo. Em estudos pré-clínicos, os medicamentos senolíticos descobertos na Mayo reduziram significativamente a inflamação, a gravidade da doença e a mortalidade da infecção por COVID em camundongos mais velhos. Essas conclusões foram publicadas na revista Science.

الأدوية المحللة للشيخوخة تقلل من أعراض فيروس كورونا المستجد (كوفيد-19) في الدراسات ما قبل السريرية

أظهر باحثو مايو كلينك وزملاؤهم في جامعة مينيسوتا أن فيروس كورونا المستجد (كوفيد-19) يفاقم التأثير الضار للخلايا الشائخة في الجسم. ففي الدراسات ما قبل السريرية، قللت الأدوية المحللة لالشيخوخة التي تم اكتشافها في مايو بشكل كبير من الالتهاب والمرض والوفيات الناجمة عن عَدوى فيروس كورونا المستجد في الفئران الأكبر سنًا. النتائج منشورة في مجلة ساينس.

抗衰老药物在临床前研究中减少COVID-19症状。

妙佑医疗国际(Mayo Clinic)的研究人员和明尼苏达大学的同事表明,COVID-19(2019冠状病毒病)加剧了体内衰老细胞的破坏性影响。在临床前研究中,妙佑医疗国际研发的抗衰老药物显著降低了老年实验鼠因COVID(冠状病毒病)感染引起的炎症、疾病和死亡率。该研究结果已发表在《科学》期刊中。

Study Identifies How COVID-19 Linked to Alzheimer’s Disease-like Cognitive Impairment

A new Cleveland Clinic-led study has identified mechanisms by which COVID-19 can lead to Alzheimer’s disease-like dementia. The findings, published in Alzheimer’s Research & Therapy, indicate an overlap between COVID-19 and brain changes common in Alzheimer’s, and may help inform risk management and therapeutic strategies for COVID-19-associated cognitive impairment.

Astronomy Meets Pathology to Identify Predictive Biomarkers for Cancer Immunotherapy

Pairing sky-mapping algorithms with advanced immunofluorescence imaging of cancer biopsies, researchers at The Mark Foundation Center for Advanced Genomics and Imaging at Johns Hopkins University and the Bloomberg~Kimmel Institute for Cancer Immunotherapy developed a robust platform to guide immunotherapy by predicting which cancers will respond to specific therapies targeting the immune system.

Cause, scope determined for deadly winter debris flow in Uttarakhand, India

The Uttarakhand region of India experienced a humanitarian tragedy on Feb. 7, 2021, when a wall of debris and water barreled down the Ronti Gad, Rishiganga and Dhauliganga river valleys. This debris flow destroyed two hydropower facilities and left more than 200 people dead or missing. A self-organized coalition of 53 scientists, including researchers from the University of Washington, came together in the days following the disaster to investigate the cause, scope and impacts.

Printing Flexible Wearable Electronics for Smart Device Applications

With the increase in demand for flexible wearable electronics, researchers have explored flexible energy storage devices, such as flexible supercapacitators, that are lightweight and safe and easily integrate with other devices. Printing electronics has proved to be an economical, simple, and scalable strategy for fabricating FSCs. In Applied Physics Reviews, researchers provide a review of printed FSCs in terms of ability to formulate functional inks, design printable electrodes, and integrate functions with other electronic devices.

COVID-19 Creates Hearing, Balance Disorders, Aggravates Tinnitus Symptoms

Evidence suggests auditory and vestibular effects should be added to the growing list of physiological impacts of COVID-19. During the 180th Meeting, Colleen Le Prell from the University of Texas at Dallas will talk about hearing and balance disorders associated with coronavirus infection and how pandemic-related stress and anxiety may aggravate tinnitus symptoms. Her presentation, “Hearing disorders secondary to infection with SARS-CoV-2,” will take place Thursday, June 10.

CHIME telescope and collaborative efforts from WVU lead to the detection of more than 500 fast radio bursts

With the help of the radio telescope located at the Dominion Radio Astrophysical Observatory, operated by the National Research Council of Canada, in British Columbia, Canada, the telescope has nearly quadrupled the number of FRB discovered to date.

Study shows when people with cerebral palsy are most likely to break bones

Researchers at Michigan Medicine found people with cerebral palsy have fragile bones that present high fracture risk, but at different times across the lifespan compared to the general population. The results helped them develop new sex-specific critical periods of bone health for this population.