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UrduA data analysis from a randomized clinical trial for stage 3 colon cancer patients by investigators at Dana-Farber Brigham Cancer Center found that patients with evidence of residual cancer in their blood after surgery to remove the cancer, may benefit from adding of celecoxib, to post surgery treatment.
Tag: Cancer Research
UChicago Medicine receives $2.8 million to empower underrepresented students in cancer research
The federally funded pathway programs strive to increase diversity and equity in the cancer research field, a key strategy to reduce health disparities in the Chicagoland area and across the country.
Brain tumors hijack circadian clock to grow
New research from Washington University in St. Louis shows that glioblastoma has an internal clock and syncs its daily rhythms to match — and take advantage of — the rhythms of its host. In this way, brain tumors grow in response to the host’s daily release of steroid hormones like cortisol.
NCCN Announces Funding for a Prostate Cancer Research Project
The NCCN Oncology Research Program (ORP) announces funding of a project that will underpin innovative research on optimal management of side effects secondary to treatment with poly ADP ribose polymerase inhibitors (PARPi).
MD Anderson’s Lauren Averett Byers receives TAMEST O’Donnell Award for seminal contributions to lung cancer research
Lauren Averett Byers, M.D., professor of Thoracic/Head & Neck Medical Oncology at The University of Texas MD Anderson Cancer Center, has received the 2025 Edith and Peter O’Donnell Award in Medicine from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST). The award recognizes her fundamental discoveries and contributions to identifying novel therapeutic strategies for small cell lung cancer (SCLC), which have paved the way for personalized treatments, even in the most highly recalcitrant cancers.
Research shows new treatment could delay cancer progression in patients with high-risk smoldering multiple myeloma
A new treatment is showing promise for people with high-risk smoldering multiple myeloma (SMM). This precancerous condition can progress to active multiple myeloma, a type of blood cancer. High-risk SMM carries a higher likelihood of progression.
New Study Reveals Key Insights on Sarcoma Rates in Military vs. Civilian Men
Researchers at the Uniformed Services University of the Health Sciences (USU) have uncovered compelling insights into the incidence of soft tissue sarcomas among U.S. active-duty servicemen, revealing significant age-related differences compared to the general male population. The findings shed light on the interplay between occupational exposures, healthcare access, and cancer risk, paving the way for targeted prevention strategies and future research.
Roswell Park Experts Report Insights on CAR T for Follicular Lymphoma, KEYNOTE-667 Combo in Hodgkin Lymphoma
The results of two important lymphoma studies led by experts at Roswell Park Comprehensive Cancer Center will be presented during oral abstract sessions this morning at the 66th annual meeting of the American Society of Hematology (ASH) in San Diego, California. Lymphoma is a type of blood cancer that causes white blood cells called lymphocytes to grow out of control and behave abnormally.
Late-breaking abstract at SUO: Novel oncolytic immunotherapy shows promise for patients with bladder cancer
A Mayo Clinic Comprehensive Cancer Center researcher will share findings from a late-breaking abstract at the 2024 Society of Urologic Oncology Annual Meeting. The study demonstrated a potentially effective treatment for patients with bladder cancer who no longer respond to the common therapy, Bacillus Calmette-Guérin (BCG).
A Cause of Hyperinflammatory Response in Lethal COVID-19 Identified
As part of the COVID-19 International Research Team, researchers at the Johns Hopkins Kimmel Cancer Center, Children’s Hospital of Philadelphia, the University of Pittsburgh and Weill Cornell Medicine discovered a novel cause of cytokine storm — the extreme inflammatory response associated with increased risk of death in COVID-19 infection.
UM researchers using AI to improve cancer research and early detection of genetic diseases
UM researchers recently developed a new genomics method with the potential to reveal the genetic mechanisms behind human health and disease. The recent publication in the journal Genome Biology offers an innovative new pathway to study the root causes of diseases like cancer and dementia to someday allow for early detection.
Schlechter named Cancer Moonshot Scholar
Chelsey Schlechter, PhD, MPH, has been chosen as a Cancer Moonshot Scholar. She is one of eleven researchers from across the country who have been selected for the prestigious honor.
Becker’s Hospital Review Names RWJBarnabas Health and Rutgers Cancer Institute to 2024’s “100+ Hospitals and Health Systems with Great Oncology Programs” List
RWJBarnabas Health, together with Rutgers Cancer Institute, has been named to Becker’s Hospital Review’s 100+ Hospitals and Health Systems with Great Oncology Programs list for 2024, for the second consecutive year.
Advancing Breast Cancer Research: Yale Cancer Center to Share Insights at International Conference
Yale Cancer Center (YCC) researchers at Yale School of Medicine will present new research at the 47th annual San Antonio Breast Cancer Symposium (SABCS) at the Henry B. Gonzalez Convention Center from December 10 to 13.
Roswell Park Launches First-of-Its-Kind Oncology Training Program for Nurse-Scientists With $2M NCI Grant
Roswell Park, in partnership with the University at Buffalo (UB) School of Nursing, has received a five-year, $2.11 million Institutional Clinical Scientist Awards (K12) grant from the National Cancer Institute to establish a training program for nurse-scientists focused around clinical translational research
How ecDNA Fuels Cancer by Breaking the Laws of Biology
How ecDNA Fuels Cancer by Breaking the Laws of Biology
Research concentrates on genes that cause tumors in the Meibomian gland
Tufts University researcher dedicated to finding treatments for cancer by researching tumors that develop in Meibomian glands, the specialized oil-secreting glands of the eyelid.
University of Chicago Medicine Comprehensive Cancer Center partners with Argonne National Laboratory to accelerate the discovery of new cancer therapies using AI
Researchers at the UChicago Medicine Comprehensive Cancer Center and Argonne National Laboratory are partnering to use AI approaches to discover new targets for cancer therapies
MRI-guided radiation therapy reduces long-term side effects for patients with prostate cancer
After a comprehensive two-year follow-up, researchers at the UCLA Health Jonsson Comprehensive Cancer Center found that MRI-guided stereotactic body radiotherapy (SBRT) for prostate cancer significantly reduced long-term side effects and improved quality of life, particularly in bowel and sexual health, compared to conventional CT-guided treatment.
Researchers make glioblastoma cells visible to attacking immune cells
Researchers at WashU Medicine have identified a possible way to make glioblastoma cells vulnerable to different types of immunotherapy. The strategy, which they demonstrated in cells in the lab, forces brain cancer cells to display targets for the immune system to attack. Their study was published in Nature Genetics.
Detección de indicios de cáncer de pulmón en el aliento exhalado
En un estudio publicado en la revista ACS Sensors, investigadores informan del desarrollo de sensores ultrasensibles a nanoescala que, en pruebas a pequeña escala, distinguen un cambio clave en la química del aliento de personas con cáncer de pulmón.
Detecting evidence of lung cancer in exhaled breath
Exhaled breath contains chemical clues to what’s going on inside the body, including diseases like lung cancer. And devising ways to sense these compounds could help doctors provide early diagnoses — and improve patients’ prospects. In a study in ACS Sensors, researchers report developing ultrasensitive, nanoscale sensors that in small-scale tests distinguished a key change in the chemistry of the breath of people with lung cancer. November is Lung Cancer Awareness Month.
Ancient Immune Defense System Plays an Unexpected Role in Cancer, MSK Researchers Find
Along with defending against pathogens, the body’s innate immune system helps to protect the stability of our genomes in unexpected ways — ways that have important implications for the development of cancer, researchers at MSK are discovering.
Only Two Weeks Remain Until the ASHG 2024 Annual Meeting
The American Society of Human Genetics (ASHG) Annual Meeting will bring together the largest gathering of human geneticists in the world in Denver, Colorado on November 5-9.
Scientific conference series aims to improve outcomes for diabetes, cancer and cardiovascular disease
The Endocrine Society, a global organization that promotes endocrinology research and clinical practice, and Keystone Symposia, a nonprofit host of conferences and symposia on a range of life science and biomedical topics, will jointly host a series of three conferences to advance endocrine research.
In Landmark Study, Immunotherapy Boosts Survival of Advanced Hodgkin Lymphoma
A treatment that rallies the immune system to destroy cancer raised the survival rate for advanced Hodgkin lymphoma patients to a remarkable 92 percent, suggesting a new standard therapy for the disease. The New England Journal of Medicine published the innovative clinical trial results this week.
Partners Celebrate Milestone in Development of the Vogel Medical Campus at Tinton Falls
Monmouth Medical Center (MMC), an RWJBarnabas Health facility, raised the final beam at the Specialty and Cancer Care Pavilion at the Vogel Medical Campus on October 8, marking a significant milestone in the system’s commitment to bring care closer to where people live, work and play across Monmouth County.
Allison Institute scientific symposium features spatial biology breakthroughs, $5 million gift to support further efforts
The James P. Allison Institute at The University of Texas MD Anderson Cancer Center hosted its second annual scientific symposium on Oct. 10. The symposium, with more than 900 attendees, featured two Nobel laureates and a $5 million gift from the David and Eula Wintermann Foundation to advance the work of the Allison Institute.
Nipple-Sparing Mastectomy: A Modern Approach to Breast Cancer Surgery
Nipple-Sparing Mastectomy (NSM) is a surgical option for patients requiring a mastectomy, in which the breast tissue is removed while the skin, nipple, and areola remain intact. This procedure allows for immediate reconstruction and offers a more natural post-surgery result, giving patients both peace of mind and a sense of body confidence. M. Michele Blackwood, MD, FACS, director of Breast Surgery and director of Women’s Oncologic Health, RWJBarnabas Health and Rutgers Cancer Institute shares more on this surgical technique.
Teresa Bowman, Ph.D., Named Chair of Developmental & Molecular Biology at Albert Einstein College of Medicine
Stem cell researcher Teresa Bowman, Ph.D., has been appointed chair of the department of developmental & molecular biology (DMB) at Albert Einstein College of Medicine after a comprehensive national search. Dr. Bowman will begin her new role on December 1, following the longtime leadership of Richard Stanley, Ph.D.
Dual immunotherapy plus chemotherapy benefits specific subset of patients with lung cancer
Researchers from The University of Texas MD Anderson Cancer Center have demonstrated that patients with metastatic non-squamous non-small cell lung cancer (NSCLC) harboring specific mutations in the STK11 and/or KEAP1 tumor suppressor genes were more likely to benefit from adding the immunotherapy tremelimumab to a combination of durvalumab plus chemotherapy to overcome treatment resistance typically seen in this patient population.
Study finds common breast cancer treatments may speed aging process
The findings, published in the Journal of the National Cancer Institute, show that markers of cellular aging—such as DNA damage response, cellular senescence, and inflammatory pathways—significantly increased in all breast cancer survivors, regardless of the type of treatment received.
Scientists Discover That Special Immune Cells Stop Metastatic Cancer
A research team at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) has discovered a natural immune mechanism in mice that stops escaped cancer cells from developing into tumors elsewhere in the body. The findings were published today in the journal Cell.
Dr. Roger Lo awarded NIH grant to tackle melanoma treatment resistance
UCLA’s Dr. Roger Lo was awarded a $2 million grant from the National Institutes of Health to investigate innovative strategies to prevent drug resistance in melanoma treatment and improve the effectiveness of MAPK inhibitors, a common treatment for patients with melanomas that carry the BRAFV600 mutation.
Case closed: Neutrons settle 40-year debate on enzyme for drug design
Scientists at ORNL used neutrons to end a decades-long debate about an enzyme cancer uses. Their findings can support the design of an inhibitor that can target aggressive cancers.
Drilling Down to the Details in Cancer Research
When an aggressive cancer launches an invasion on the human body, anything that can be done to slow down or better understand that fast-paced assault is going to be a bonus.
Vulnerable Patients Have a Decreased Mortality Risk When Treated at Commission on Cancer-Accredited Hospitals
Highly vulnerable patients treated at hospitals accredited by the ACS Commission on Cancer were more likely to receive guideline-based care and less likely to die.
Comprehensive cancer research from Dana-Farber to lead ESMO Congress 2024
Novel treatments, including targeted therapies and antibody drug conjugates, as well as research into improving quality of life for patients with breast cancer, headline studies led by Dana-Farber Cancer Institute and presented at the European Society of Medical Oncology (ESMO) Congress 2024 in Barcelona, Spain.
New law regulating out-of-pocket drug spending saves cancer patients more than $7,000 a year, study finds
As prescription oral chemotherapies have become a common form of cancer treatment, some patients were paying more than $10,000 a year for medications. A new study finds that efforts to cap prescription drug spending are yielding significant out-of-pocket savings for these patients.
Cancer Research Institute (CRI) Appoints Alicia Zhou, PhD, as Chief Executive Officer to Advance Next Generation of Cancer Immunotherapy Science and Innovation
The Cancer Research Institute (CRI) has appointed Alicia Zhou, PhD, as its new Chief Executive Officer (CEO).
Cancer Research in Space for Life on Earth: Wake Forest Institute for Regenerative Medicine Selected Through International Space Station National Lab Solicitation in Partnership with NASA
The Wake Forest Institute for Regenerative Medicine (WFIRM) is honored to announce its selection for a pioneering cancer research project that will take place aboard the International Space Station (ISS).
Researchers identify factor that drives prostate cancer-causing genes
Researchers at the University of Michigan Health Rogel Cancer Center have uncovered a key reason why a typically normal protein goes awry and fuels cancer. They found the protein NSD2 alters the function of the androgen receptor, an important regulator of normal prostate development.
TGF-Beta and RAS Signaling Are Both Required for Lung Cancer Metastasis, Study Finds
MSK researchers have identified two signaling pathways that work together to spur the spread of lung cancer. Taking away one of those signals could help slow or stop metastasis, findings in animal models suggest.
Global Experts Converge at CICON24 to Unveil Groundbreaking Advances in Cancer Immunotherapy, September 8-11, 2024 at National Harbor, MD
CRI is co-hosting CICON24 to illuminate pioneering advances in cancer immunotherapy research starting September 8 in National Harbor, MD.
Age-Related Changes in Male Fibroblasts Increase Treatment-Resistant Melanoma
Age-related changes in the fibroblasts, cells that create the skin’s structure, contribute to the development of aggressive, treatment-resistant melanoma in males, according to research in mice by the Johns Hopkins Kimmel Cancer Center.
Novel Study Reveals How Aging Immune System Fuels Cancer Growth, Potentially Opening New Avenues for Prevention
A novel study by researchers at the Icahn School of Medicine at Mount Sinai addresses a critical yet under-explored question in cancer research: Why is aging the biggest risk factor for cancer? The study reveals how an aging immune system spurs tumor growth, offering new insights into cancer prevention and treatment, especially for older adults.
MSK Research Highlights, September 3, 2024
New research from Memorial Sloan Kettering Cancer Center (MSK) uses cryo-electron microscopy to shed new light on the ubiquitin; could help predict the risk of blood clots in cancer patients; reveals why micronuclei burst, accelerating aggressive cancers; and surveys healthcare providers about the benefits and risks of commercial genetic testing.
SHRO Scientist Named FDA-AACR Cancer Research Fellow
Canio Martinelli, M.D., MSc, GYN-OB resident at the University of Messina and visiting Ph.D. student in Translational Molecular Medicine and Surgery at the Sbarro Health Research Organization (SHRO), Temple University, has been honored with the 2024-2025 FDA-AACR Oncology Educational Fellowship.
Americans face disparities in exposure to tobacco on streaming platforms
Tens of millions of Americans are being exposed to tobacco content on streaming services, according to new research from The University of Texas MD Anderson Cancer Center.
Rutgers Researchers Explore Potential for Artificial Intelligence (AI) in Biomedical Science
New Brunswick, N.J., August 21, 2024 – Generative artificial intelligence (AI) powered by human language has made remarkable progress and gained widespread use through tools such as ChatGPT. While it is mostly known for helping with reading and writing, scientists are…