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UC San Diego Computer Scientist Plays Major Role in $25M Cancer Grand Challenges Project

June 16, 2022 sarah JonasFeature

University of California San Diego computer scientist Vineet Bafna is part of a team of world-class researchers that has been awarded a five-year, $25 million Cancer Grand Challenges grant to learn how the destructive genetic lesion extrachromosomal DNA (ecDNA) influences numerous cancers and to identify possible therapies.

Ludwig Cancer Research Study Reveals How Circular ecDNA is Generated and Drives Drug Resistance in Cancer

December 24, 2020 sarah JonasResearch Results

Researchers led by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the mystery of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to generate drug resistance in cancer.