ASU bioengineer Benjamin Bartelle studies the innate immune system, which serves as the body’s first line of defense for many disease processes.
Tag: Innate Immune System
Icahn School of Medicine at Mount Sinai Researchers Awarded $15.1 Million Grant to Explore Immune Rejection of Transplanted Organs
Striving to improve organ transplant survival rates, internationally renowned researchers in immunology and bioengineering at the Icahn School of Medicine at Mount Sinai have received $15.1 million from the National Institute of Allergy and Infectious Diseases (NIAID) to lead a novel, five-year multi-center research program that will explore trained immunity—the innate immune system’s ability to remember infections and other insults—as a target for preventing organ transplant rejection.
Immune cells have a backup mechanism
The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses. Upon mutation-induced loss of TBK1 function, patients show an increased susceptibility to viral infections.
PFAS Can Suppress White Blood Cell’s Ability to Destroy Invaders
In a new study, researchers found that the PFAS chemical GenX suppresses the neutrophil respiratory burst – the method white blood cells known as neutrophils use to kill invading pathogens.