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DALLAS – Jan. 5, 2021 – Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in a highly aggressive form of non-small cell lung cancer (NSCLC). These findings could pave the way for new treatments for patients with mutations in two key genes – KRAS and LKB1. Patients whose tumors contain both of these mutations, known as KL tumors, have poor outcomes and usually do not respond to immunotherapy.
August 19, 2020 (DALLAS, TEXAS) – For decades, physicians have known that many kinds of cancer cells often spread first to lymph nodes before traveling to distant organs through the bloodstream. New research from Children’s Medical Center Research Institute at UT Southwestern (CRI) provides insight into why this occurs, opening up new targets for treatments that could inhibit the spread of cancer.
The American College of Radiology® (ACR®) Center for Research and Innovation™ (CRI) will serve as the imaging coordination center for the multicenter COVID-19 Observational Study (CORAL) led by Dr. Catherine “Terri” L. Hough of the Oregon Health & Science University. The CORAL Study is part of the Prevention & Early Treatment of Acute Lung Injury (PETAL) Network, a consortium of academic and affiliated hospitals across the United States – funded by the National Heart, Lung, and Blood Institute, part of the National Institutes of Health – to conduct clinical trials in patients with or at risk for critical illness, including acute respiratory distress syndrome.
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