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UrduResearch from the University of Michigan Rogel Cancer Center could provide a new approach to treating an aggressive form of breast cancer. A study led by Duxin Sun, Ph.D., found that targeting the immune microenvironment in lymph nodes and tumors simultaneously led to long-term tumor remission in mice models of metastatic triple negative breast cancer.
Tag: Breast Cancer
Moffitt Researchers Identify Pathway that Regulates Lipid Synthesis and Contributes to Tumor Survival
In a new study published in the journal Cell Reports, Moffitt Cancer Center researchers show that cancer cells in an acidic environment undergo lipid synthesis and accumulation. The team identified the key signaling molecules responsible for these changes and discovered that these alterations are associated with poor outcomes and disease progression among breast cancer patients.
MD Anderson Research Highlights for May 4, 2022
Featured studies include clinical advances with a new combination therapy targeting angiogenesis in platinum-resistant ovarian cancer and a promising immunotherapy combination for kidney cancer, plus laboratory studies that focus on targeting ferroptosis in specific lung cancers, developing chimeric antigen receptor (CAR) T cell therapies for blastic plasmacytoid dendritic cell neoplasms, and characterizing racial and ethnic disparities in breast cancer early detection.
Could exercise counteract cardiotoxic chemotherapy for women with breast cancer
When you’re a breast cancer survivor, the last thing you need is another health scare. So, it’s concerning to know that up to 48 per cent of breast cancer patients will go on to fight heart disease as a direct result of chemotherapy.
Does Multiple Sclerosis Play a Role in Cancer Screening and Diagnosis?
Women with multiple sclerosis (MS) are less likely to have breast cancers detected through cancer screenings than women without MS, according to new research published in the April 27, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. Conversely, researchers also found that people with MS are more likely to have colorectal cancers detected at an early stage than those without MS.
Mount Sinai Researchers Discover How Early-Stage Breast Cancer Can Become a Silent Killer in Some Patients
Mount Sinai researchers have discovered a previously unknown mechanism in which not-yet-malignant cells from early breast cancer tumors travel to other organs and, eventually, “turn on” and become metastatic breast cancer.
SUSAN G. KOMEN® NAMES TOP BREAST CANCER EXPERTS AS SCIENTIFIC ADVISORS
Susan G. Komen has appointed 10 world-renowned breast cancer researchers and two patient advocates to serve as advisors to the organization. They join a distinguished group of breast cancer researchers, clinicians and advocates who help guide Komen’s work so that people who have been diagnosed with breast cancer can live longer, better lives.
STUDY FINDS DECREASE IN RACIAL DISPARITY AND INCREASE IN SURVIVAL RATES IN METASTATIC BREAST CANCER PATIENTS DUE TO MEDICAID EXPANSION
Findings from Study Led by Susan G. Komen Scholars Published in JAMA Oncology
Cardamonin Shows Promise for Treating Aggressive Breast Cancer
Cardamonin — a natural compound found in the spice cardamom and other plants — could have therapeutic potential for triple-negative breast cancer, according to a new study using human cancer cells. The findings also show that the compound targets a gene that helps cancer cells elude the immune system.
Antioxidant, Inflammation Levels May Reveal New Diagnostic Tool for Breast Cancer
A new study that analyzes levels of antioxidants and stress markers in the blood could lead to a new diagnostic tool for breast cancer. The research will be presented this week in Philadelphia at the American Physiological Society’s (APS) annual meeting at Experimental Biology 2022.
Light Therapy Improves Breast Cancer Survivors’ Sleep
Cancer alters the circadian rhythm functions, which results in fatigue and disrupted sleep/wake patterns. Dr. Horng-Shiuann Wu studies how using extremely bright light to “reset” a female breast cancer patient’s internal clock can help them sleep better.
Houston Methodist receives $25 million to expand cancer center
Houston Methodist has received a $25 million philanthropic gift from Dr. Mary and Ron Neal to expand the hospital system’s cancer center.
Comparing African and European populations leads to breast cancer risk discovery
By comparing genetic data from European and African population groups, scientists at UChicago Medicine Comprehensive Cancer Center have identified seven new regions of the human genome that are associated with increased breast cancer risk. The findings were published in Nature Communications.
Fat-Secreted Molecule Lowers Response to Common Cancer Treatment
Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study led by researchers from the Johns Hopkins Kimmel Cancer Center.
Chemo helps breast cancer cells get their ‘foot in the door’ to the lungs
A new study adds to the evidence that chemotherapy enhances cancer’s spread beyond the primary tumor, showing how one chemo drug allows breast cancer cells to squeeze through and attach to blood vessel linings in the lungs.
Breast cancer patients can navigate care at home with a new skills kit
With the exception of skin cancers, breast cancer is the most common cancer affecting women. This year more than 330,000 new cases of breast cancer are expected to be diagnosed according to the American Cancer Society. The COVID-19 pandemic has further challenged these vulnerable patients as well as the thousands of others currently going through cancer treatment and recovery, making some hesitant to leave their homes for necessary screenings, treatments, and consults.
Yale Cancer Center Study Shows New Strategy to Fight Drug Resistance in HER2-Positive Breast and Ovarian Cancers
New findings by researchers at Yale Cancer Center demonstrate a novel strategy to treat tumor growth in breast and ovarian cancers characterized by HER2 gene amplification, an increase in the number of copies of a gene.
Cleveland Clinic Launches First-of-its Kind Preventive Breast Cancer Vaccine Study
Cleveland Clinic researchers have opened a novel study for a vaccine aimed at eventually preventing triple-negative breast cancer, the most aggressive and lethal form of the disease.
$2.1 Million Gift Launches Comprehensive Breast Cancer Database
Philanthropists Richard and Carol Dean Hertzberg have committed $2.1 million to develop and maintain the Dean-Hertzberg Breast Cancer Database System Initiative at UC San Diego Health Moores Cancer Center to support the work of Anne Wallace, MD and her collaborators at Moores Cancer Center.
Intervention eliminates Black-white gaps in survival from early-stage breast and lung cancer
A new study shows that system-level changes to the way cancer care is delivered can also eliminate Black-white disparities in survival from early-stage lung and breast cancer. By identifying and addressing obstacles that kept patients from finishing radiation treatments for cancer, the intervention improved five-year survival rates for all patients and erased the survival gap between Black and white patients. Findings will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting.
Improving Breast Cancer Outcomes in Black Women: Time for a Change
Each participant will provide a 3 to 5-minute summary highlighting her panel presentation remarks for the media. (Reporters are asked to view the panel session the day before). Then we will open up the virtual meeting call for questions from the media.
High-dose radiation thwarts tumor growth in patients with advanced lung cancer
High-dose radiation therapy can be used to lengthen progression-free survival for people with advanced lung cancer when systemic therapy has not fully halted the growth or spread of metastases, according to a new study. Findings will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting.
Surgery has survival benefits for male Stage IV breast cancer patients who are receptive to systemic therapy
Men with Stage IV breast cancer and known estrogen (ER) and progesterone receptor (PR) status benefit from surgical intervention and from trimodal therapy (systemic therapy, surgery, and radiation).
Secure media credentials to cover “Improving Breast Cancer Outcomes in Black Women: Time for a Change”
A live press briefing featuring a panel of nationally recognized experts will follow their presentation “Improving Breast Cancer Outcomes in Black Women: Time for a Change” at the American College of Surgeons (ACS) annual ACS Clinical Congress being held virtually (October 23–27).
The Medical Minute: You got your mother’s blue eyes. Will you get her breast cancer, too?
Family traits can be a source of pride – and a source of worry. Fortunately, only 5% to 10% of all cancers can be linked to a genetic mutation passed on from your mom or dad. How can you gauge your genetic risk?
Artificial Intelligence Tool Improves Accuracy of Breast Cancer Imaging
A computer program trained to see patterns among thousands of breast ultrasound images can aid physicians in accurately diagnosing breast cancer, a new study shows.
Active Living After Cancer program improves physical functioning of breast cancer survivors
Breast cancer survivors who participated in Active Living After Cancer, an evidence-based 12-week group program, markedly increased their physical activity and ability to accomplish the basic pursuits of daily life, researchers from The University of Texas
MD Anderson Cancer Center reported today in Cancer.
New study shows that different types of cancers are likely to spread to specific areas of the brain
Brain metastasis occurs when cancer in one part of the body spreads to the brain. The lifetime incidence of such metastatic brain tumors in cancer patients is between 20%-45%, research shows.
MD Anderson Research Highlights for September 22, 2021
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recently published studies in basic, translational and clinical cancer research from MD Anderson experts. Current advances include a new method to measure breast cancer response, a new immunotherapy approach for multiple myeloma, characterization of the immune landscape of cholangiocarcinoma, a new contrast agent to improve molecular imaging techniques, and new treatment targets in breast, gynecologic and pancreatic cancers.
ESMO: New drug shows promise in treating early-stage breast cancer
Early results from a UCLA-led clinical trial found treating women with estrogen receptor (ER)-positive and human epidermal growth factor receptor-2 (HER2)-negative early breast cancers with a novel type of anti-hormonal therapy, called an oral selective estrogen receptor degrader (SERD), led to clinically meaningful reductions in tumor activity prior to surgery.
ESMO: HER2-targeting antibody-drug improves progression-free survival for women with deadly form of advanced breast cancer
A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center has found that treating women with HER2 positive metastatic breast cancer with the HER2-targeting antibody-drug conjugate trastuzumab deruxtecan (T-DXd) significantly prolongs the length of time the disease is controlled and cancer growth is halted when compared to the current standard of care, trastuzumab emtansine (T-DM1).
How a plant virus could protect and save your lungs from metastatic cancer
Using a virus that grows in black-eyed pea plants, researchers developed a new therapy that could keep metastatic cancers from spreading to the lungs, as well as treat established tumors in the lungs.
Legislation may help identify breast cancer earlier in certain at-risk women
Laws designed to help women with increased risk for missed breast cancer diagnoses may help catch the disease earlier, according to Penn State College of Medicine researchers.
Rutgers Cancer Institute of New Jersey Expert Available for Comment on Proton Therapy for Breast Cancer
New Brunswick, N.J., August 23, 2021 – Proton therapy is a type of radiation therapy treatment that targets a tumor in a very precise way, emerging as a unique modality for breast cancer due to the ability to minimize exposure surrounding healthy…
MERCY MEDICAL CENTER UTILIZES SINGLE-DOSE BREAST CANCER RADIOTHERAPY FOR OLDER AMERICANS
This National Senior Citizens Day, Sat., August 21st, Mercy Medical Center is emphasizing Intraoperative Radiation Therapy (IORT), a single dose of targeted radiation delivered from inside the breast while the patient remains asleep immediately following the removal of the tumor.
Physical activity associated with better cognition in breast cancer patients
There is a strong association between high levels of physical activity and the ability to maintain cognitive function among breast cancer patients treated with chemotherapy, according to new research from Washington University School of Medicine in St. Louis.
CAP Foundation Announces $2M Fundraising Campaign Supporting Cancer Screening, Pathology
The College of American Pathologists (CAP) Foundation announced in July 2021 a new fundraising campaign with a minimum goal of $2 million that will secure life-saving cancer screening and pathology education and training programs for the next decade.
Artificial Intelligence aids in discovery of new prognostic biomarkers for breast cancer
Scientists at Case Western Reserve University have used Artificial Intelligence (AI) to identify new biomarkers for breast cancer that can predict whether the cancer will return after treatment—and which can be identified from routinely acquired tissue biopsy samples of early-stage breast cancer.
Statins may improve survival for triple-negative breast cancer patients
A study led by researchers from The University of Texas MD Anderson Cancer Center found a significant association between cholesterol-lowering drugs commonly known as statins and survival rates of triple-negative breast cancer patients. Since statins are low in cost, easy to access and produce minimal side effects, this could have an important impact on outcomes for this aggressive disease.
Shih-Ting (Christine) Wang: Designing Materials for Biomedicine
Using DNA-based assembly, the Center for Functional Nanomaterials postdoc has assembled functional proteins into ordered lattices and coated nanostructures for drug delivery.
Mayo Clinic scientists advance breast, ovarian cancer research with cryo-electron microscopy
Using advanced imaging technology, Mayo Clinic scientists have provided an unprecedented understanding of the BRCA1-BARD1 protein complex, which is often mutated in patients with breast or ovarian cancer. Their paper, published in Nature, identifies aspects of how BRCA1-BARD1 functions, supporting future translational research, cancer prevention efforts and drug development.
Mount Sinai Researchers Develop Novel Therapy That Could Be Effective in Many Cancers
Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in Cancer Discovery, a journal of the American Association for Cancer Research, in July.
Mount Sinai researchers develop novel therapy that could be effective in many cancers
New York, NY (July 23, 2021) — Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in Cancer Discovery , a…
Mayo Clinic research suggests women over 65 be offered hereditary cancer genetic testing
A new study by Fergus Couch, Ph.D., of Mayo Clinic Cancer Center, along with collaborators from the CARRIERS consortium, suggests that most women with breast cancer diagnosed over 65 should be offered hereditary cancer genetic testing. The study was published Thursday, July 22, in the Journal of Clinical Oncology.
FAU Nursing Faculty Member Receives NIH K01 Grant for Breast Cancer Research
Tarsha Jones, Ph.D., principal investigator and an assistant professor of nursing at FAU’s Christine E. Lynn College of Nursing, has received the National Institute of Health (NIH) K01 Career Development Award, a five-year, $772,525 award for a project titled, “Decision Support for Multigene Panel Testing and Family Risk Communication among Racially/Ethnically Diverse Young Breast Cancer Survivors.”
Bidirectional impact of cardiovascular disease, cancer in Blacks focus of new AHA center
Cardiovascular disease and cancer, the nation’s top two killers, share common ground like obesity and chronic inflammation, as well as a disproportionate impact on Black Americans. A new American Heart Association-funded center at the Medical College of Georgia is working…
Change Agent
The UNM Comprehensive Cancer Center helps patients with high-complexity cases. Elyse Eckart’s experience with breast cancer has led her to take on new challenges and embrace tasks and activities she may not have before. She’s also giving back to the community.
Hundreds of chemicals, many in consumer products, could increase breast cancer risk
List includes potential carcinogens that act by stimulating production of hormones that fuel breast tumors
New approach eradicates breast cancer in mice
CHAMPAIGN, Ill. — A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks…
Program seeks to reduce preventable cancers with free screening, same-day results
George Mason faculty Michelle Williams leads program evaluation determining feasibility of See, Test, & Treat Program to addresses barriers and improve health outcomes for cervical, breast, and oral cancer among under-served women in Mississippi