HERSTORY is focused on understanding genetic, environmental, socio-economic, and other determinants of cancer in women with a family history of the disease.
Tag: Cancer Genetics
Robotic surgery expertise increases odds for those who battle stomach cancer like Toby Keith
Toby Keith, John Wayne and Fred Rogers are among many famous figures who passed from stomach cancer, a particularly deadly form of cancer. Now, robotic surgery is improving the odds for cancer patients. Matthew Porembka, M.D. is part of a…
Researchers Characterize the Immune Landscape in Cancer
Researchers from the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium of the National Institutes of Health, The University of Texas MD Anderson Cancer Center, Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and others, have unveiled a detailed understanding of immune responses in cancer, marking a significant development in the field. The findings were published in the February 14 online issue of Cell. Utilizing data from more than 1,000 tumors across 10 different cancers, the study is the first to integrate DNA, RNA, and proteomics (the study of proteins), revealing the complex interplay of immune cells in tumors. The data came from the Clinical Proteomic Tumor Analysis Consortium (CPTAC), a program under the National Cancer Institute.
St. Jude tool targets cancer-causing fusions’ weak spot
Scientists at St. Jude Children’s Research Hospital comprehensively characterized oncogenic fusions in pediatric cancer, providing proof-of-principle for genetic engineering-based therapies.
Comparing African and European populations leads to breast cancer risk discovery
By comparing genetic data from European and African population groups, scientists at UChicago Medicine Comprehensive Cancer Center have identified seven new regions of the human genome that are associated with increased breast cancer risk. The findings were published in Nature Communications.
The Medical Minute: You got your mother’s blue eyes. Will you get her breast cancer, too?
Family traits can be a source of pride – and a source of worry. Fortunately, only 5% to 10% of all cancers can be linked to a genetic mutation passed on from your mom or dad. How can you gauge your genetic risk?
Two Studies Seek to Go Beyond the GIST of Intestinal Tract Cancer
UC San Diego researchers identify the mutational drivers for gastrointestinal stroma tumors in the stomach and find a potential drug to treat a subset of GIST tumors afflicting the young.