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UrduResearchers say that genomic surveillance to mitigate and contain COVID-19 is equally crucial to detect variants that are phenotypically or antigenically different well before they spread throughout the U.S. and the rest of the world. Genomic surveillance leverages applications of next-generation sequencing and phylogenetic methods to facilitate greater early anticipation as well as initiation of effective strategies to mitigate and contain outbreaks of SARS-CoV-2 variants and other novel viruses.
Category: Research Results
Neuroactive Steroids May Induce Prolonged Antidepressant Effects by Altering Brain States
A new study by researchers from Tufts University School of Medicine and Sage Therapeutics discovered that neurosteroids (allopregnanolone analogs) may alter network states in brain regions involved in emotional processing, which may explain the prolonged antidepressant effects of these compounds.
Improving soil carbon measurements empowers African farmers
Researchers test new, inexpensive device to provide critical information
The Covid-19 pandemic has widened the gap between the rich and the poor, and it’s not finished yet
New study from University of Sheffield highlights how the pandemic continues to widen the gap between the rich and the poor
Reduction of Salt in Bread Reviewed for Impact on Taste, Feasibility
Scientists focus on nutritional and sensory quality research.
Indiana’s Census 2020 results: Metro areas and minority populations fuel state’s growth
Latest results from the 2020 Census show that Indiana’s population growth over the past decade largely was driven by gains in a handful of metropolitan areas and exclusively through gains among the state’s minority populations, according to analysis by the Indiana Business Research Center at Indiana University’s Kelley School of Business.
Wearable temperature sensor provides early warning for complications in cancer patients
A wearable temperature sensor provides early warning for certain complications in cancer patients
Weight Fluctuations May Predict Poor Outcomes in Adults with Kidney Disease
• In individuals with kidney disease, those with high body mass index variability faced higher risks of needing kidney replacement therapy, experiencing a heart attack, experiencing a stroke, and dying prematurely.
Warfare, not climate, is driving resurgent hunger in Africa, says study
After years of progress on food security, some nations see sharp reversals
Researchers take step toward next-generation brain-computer interface system
Brain-computer interfaces (BCIs) are emerging assistive devices that may one day help people with brain or spinal injuries to move or communicate. BCI systems depend on implantable sensors that record electrical signals in the brain and use those signals to drive external devices like computers or robotic prosthetics.
Study takes unprecedented peek into life of 17,000-year-old mammoth
An international research team has retraced the astonishing lifetime journey of an Arctic woolly mammoth, which covered enough of the Alaska landscape during its 28 years to almost circle the Earth twice.
Black hole size revealed by its eating pattern
The feeding patterns of black holes offer insight into their size, researchers report. A new study revealed that the flickering in the brightness observed in actively feeding supermassive black holes is related to their mass.
Study suggests reforms to prevent bribery and corruption at major sporting events
Bribery and corruption at huge sporting events – such as the Olympics, World Cups and UEFA club competition finals – can and must be prevented, a new paper from the University of Portsmouth argues.
Human Sperm Mutations that can Cause Disease in Children Identified
UC San Diego researchers have described a new method for observing and counting mutations in sperm, and how to use this data to predict the likely impact of these mutations on future children.
TV ads inspire investment interest
Stock trading volumes in the United States have soared over the last year and much of it seems to be driven by retail investors. In a new Cornell University study researchers show that advertising is one of the most noteworthy influences behind retail stock investing.
First-time opioid prescriptions got shorter, less potent after CDC guidelines
Five years ago, CDC released an evidence-based guideline to help doctors treat their patients’ pain while balancing the risks and benefits of prescription opioid medications. A new study suggests it may have started to have an effect in the first two years after its launch.
Southeast’s gray foxes may be struggling for survival
A new study published by researchers from the University of Georgia suggests competition for food from coyotes—a relative newcomer to the Southeast—may be putting pressure on foxes, particularly the gray fox.
No adverse cognitive effects of ketamine or esketamine for treatment-resistant depression
Used for the treatment of depression that does not respond to standard antidepressant medications, the anesthesia drug ketamine – and the related drug esketamine, recently approved for depression treatment – has no important adverse effects on memory, attention, or other cognitive processes, concludes a systematic review of medical research in the September/October issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Adoptive Cell Therapy Plus Checkpoint Inhibitors Show Promise in Non-Small Cell Lung Cancer
Researchers in Moffitt Cancer Center’s Lung Cancer Center of Excellence believe a combination of checkpoint inhibitors with adoptive cell therapy could be the answer for non-small cell lung cancer patients. Results of their investigator-initiated phase 1 clinical trial evaluating the checkpoint inhibitor nivolumab in combination with tumor infiltrating lymphocyte (TIL) therapy was published today in Nature Medicine.
Mountain lions moved less, downsized territory during LA’s pandemic shutdown
As people sheltered in place at the onset of the COVID-19 pandemic, sightings of wildlife in urban areas helped spawn a meme, “Nature is healing,” that reflected an intuitive belief: Carnivores were stretching their legs, and their ranges, by expanding into long-lost territory.
For psoriasis, targeting skin protein may help control inflammation
Targeting a protein found in the skin may reduce the severity of psoriasis, a Michigan Medicine study found. Using a mouse model to mimic psoriasis, researchers found changing levels of interferon kappa altered the severity of inflammation.
Ultrasound remotely triggers immune cells to attack tumors in mice without toxic side effects
A new cancer immunotherapy pairs ultrasound with specially engineered CAR T cells to destroy malignant tumors while sparing normal tissue. The new experimental therapy significantly slowed down the growth of solid cancerous tumors in mice.
Yale Cancer Center Perspective Highlights New Advances for NSCLC
A new publication by Yale Cancer Center highlights recent breakthrough therapies developed to treat non-small cell lung cancer (NSCLC). The goal of the study is to provide views on how basic science advances will impact clinical research areas to help influence how NSCLC will be managed over the coming decade.
New Blood: Lab-Grown Stem Cells Bode Well for Transplants, Aging Research
UC San Diego researchers develop a method to grow hematopoietic stem cells in culture, with clinical implications for bone marrow transplants and aging research.
In transplant recipients, COVID-19 vaccines reduce infection and mortality risks
Vaccination against SARS-CoV-2 substantially lowers the risks of “breakthrough” infections and death due to COVID-19 in adult organ transplant recipients, according to a pair of research letters in Transplantation, the official Journal of The Transplantation Society and the International Liver Transplantation Society. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Low-cost 3D Method Rapidly Measures Disease Impacts on Florida’s Coral Reefs
A low-cost and rapid 3D technique is helping scientists to gain insight into the colony- and community-level dynamics of the poorly understood stony coral tissue loss disease responsible for widespread coral death throughout the Tropical Western Atlantic. They adapted Structure-from-Motion (SfM) photogrammetry to generate 3D models for tracking lesion progression and impacts on diseased coral colonies. They combined traditional diver surveys with 3D colony fate-tracking to determine the impacts of disease on coral colonies throughout Southeast Florida.
Low-cost 3D Method Rapidly Measures Disease Impacts on Florida’s Coral Reefs
A low-cost and rapid 3D technique is helping scientists to gain insight into the colony- and community-level dynamics of the poorly understood stony coral tissue loss disease responsible for widespread coral death throughout the Tropical Western Atlantic. They adapted Structure-from-Motion (SfM) photogrammetry to generate 3D models for tracking lesion progression and impacts on diseased coral colonies. They combined traditional diver surveys with 3D colony fate-tracking to determine the impacts of disease on coral colonies throughout Southeast Florida.
Batters move their heads to keep their eyes on the ball
Do baseball batters actually keep their eye on the ball? A review of the few film- and lab-based studies on the subject suggests that yes, indeed, batters’ eyes are watching the pitched ball. But they’re moving their heads, and not their eyes, to direct their gaze.
Batters move their heads to keep their eyes on the ball
Do baseball batters actually keep their eye on the ball? A review of the few film- and lab-based studies on the subject suggests that yes, indeed, batters’ eyes are watching the pitched ball. But they’re moving their heads, and not their eyes, to direct their gaze.
A fast, accurate system for quickly solving stubborn RNA structures from pond scum, the SARS-CoV-2 virus and more
Naked RNA molecules are too floppy for high-res 3D imaging, but a system developed at SLAC and Stanford fixes that. It reveals detailed RNA structures from a pond scum critter and COVID-19 virus.
A fast, accurate system for quickly solving stubborn RNA structures from pond scum, the SARS-CoV-2 virus and more
Naked RNA molecules are too floppy for high-res 3D imaging, but a system developed at SLAC and Stanford fixes that. It reveals detailed RNA structures from a pond scum critter and COVID-19 virus.
New technique illuminates DNA helix
Cornell researchers have identified a new way to measure DNA torsional stiffness – how much resistance the helix offers when twisted – information that can potentially shed light on how cells work.
New technique illuminates DNA helix
Cornell researchers have identified a new way to measure DNA torsional stiffness – how much resistance the helix offers when twisted – information that can potentially shed light on how cells work.
One-dimensional red phosphorous glows in unexpected ways
In a study published in Nature Communications, an international team led by Aalto University researchers has found that fibrous red phosphorous, when electrons are confined in its one-dimensional sub-units, can show large optical responses – that is, the material shows strong photoluminescence under light irradiation. Red phosphorous, like graphene, belongs to a unique group of materials discovered in 2017 called one-dimensional van der Waals (1D vdW) materials.
One-dimensional red phosphorous glows in unexpected ways
In a study published in Nature Communications, an international team led by Aalto University researchers has found that fibrous red phosphorous, when electrons are confined in its one-dimensional sub-units, can show large optical responses – that is, the material shows strong photoluminescence under light irradiation. Red phosphorous, like graphene, belongs to a unique group of materials discovered in 2017 called one-dimensional van der Waals (1D vdW) materials.
Modeling uncovers an “atomic waltz” for atom manipulation
Researchers at the University of Vienna’s Faculty of Physics in collaboration with colleagues from the Oak Ridge National Laboratory in the USA have uncovered a non-destructive mechanism to manipulate donor impurities within silicon using focused electron irradiation.
Readiness to punish others for selfish behaviour explained by functional brain connections
The stronger the functional brain connections, the less inclined someone is to punish others for unfair behaviour.
Insidious coral killer invading Palmyra Atoll reef
The reefs at Palmyra Atoll, a small outlying atoll in the equatorial Pacific Ocean, have been undergoing a shift from stony corals to systems dominated by corallimorphs, marine invertebrates that share traits with both anemones and hard corals.
“Experienced” Mouse Mothers Tutor Other Females to Parent, Helped by Hormone Oxytocin
The best way to become a good mother just might be learning from an experienced one, if new research on female mice is any indication, according to a Rutgers researcher who filmed thousands of hours of interaction between female mice and found that mouse mothers are outstanding tutors.
World-first COVID vaccine booster randomized clinical trial in transplant patients proves third shot is very effective
The study enrolled 120 transplant patients between May 25th and June 3rd. None of them had COVID previously and all of them had received two doses of the Moderna vaccine. Half of the participants received a third shot of the vaccine (at the 2-month mark after their second dose) and the other half received placebo.
The primary outcome was based on antibody level greater than 100 U/ml against the spike protein of the virus. In the placebo group – after three doses (where the third dose was placebo), the response rate was only 18% whereas in the Moderna three-dose group, the response rate was 55%.
World-first COVID vaccine booster randomized clinical trial in transplant patients proves third shot is very effective
The study enrolled 120 transplant patients between May 25th and June 3rd. None of them had COVID previously and all of them had received two doses of the Moderna vaccine. Half of the participants received a third shot of the vaccine (at the 2-month mark after their second dose) and the other half received placebo. The primary outcome was based on antibody level greater than 100 U/ml against the spike protein of the virus. In the placebo group – after three doses (where the third dose was placebo), the response rate was only 18% whereas in the Moderna three-dose group, the response rate was 55%.
妙佑医疗国际一项为期20年的研究表明大多数患有遗传性心脏病的运动员有望重返赛场
年轻运动员一旦被诊断出患有遗传性心脏病（如可导致心源性猝死的长QT综合征），其运动生涯往往就会画上句号。
17-Year Study of Children Associates Poverty with Smaller, Slower-Growing Subcortical Regions
Research from the lab of Deanna Barch and Joan Luby shows a lasting relationship between childhood poverty, brain development.
الدراسات التي أجرتها مايو كلينك لمدة 20 عامًا تشير إلى إمكانية إدارة العودة إلى ممارسة الرياضة للرياضيين المصابين بأمراض القلب الوراثية
مدينة روتشستر، ولاية مينيسوتا- لطالما كان تشخيص مرض القلب الوراثي مثل متلازمة كيو تي الطويلة، التي يمكن أن تسبب الموت القلبي المفاجئ، أمرًا صعبًا بالنسبة للرياضيين الشباب.
Estudo da Mayo Clinic de 20 anos sugere que o retorno à prática esportiva é viável para atletas com a maioria das doenças cardíacas genéticas
Receber o diagnóstico de uma doença cardíaca genética, como a síndrome do QT longo, que pode causar morte súbita cardíaca, é considerado o fim de carreira para jovens atletas.
Estudio de Mayo Clinic durante 20 años plantea posibilidad de que deportistas con enfermedades cardíacas genéticas vuelvan al deporte
Desde hace mucho tiempo, los deportistas jóvenes se han visto obligados a poner fin a la práctica del deporte cuando se les diagnostica una enfermedad cardíaca genética, como síndrome del intervalo QT largo, afección capaz de ocasionar muerte cardíaca repentina.
People With Stroke Who Walk 30 Minutes Per Day May Have 54% Lower Risk of Death
MINNEAPOLIS – A new study shows that people who walk or garden at least three to four hours per week, or bike at least two to three hours per week, or the equivalent after having a stroke may have a 54% lower risk of death from any cause. The research is published in the August 11, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study found the most benefit for younger stroke survivors. When people under the age of 75 exercised at least that amount, their risk of death was reduced by 80%.
Do Some Diabetes Drugs Reduce the Risk of Alzheimer’s?
MINNEAPOLIS – People taking certain drugs to lower blood sugar for type 2 diabetes had less amyloid in the brain, a biomarker of Alzheimer’s disease, when compared to both people with type 2 diabetes not taking the drugs and people without diabetes. The new study, published in the August 11, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology, also found people taking these drugs, called dipeptidyl peptidase-4 inhibitors, showed slower cognitive decline than people in the other two groups.
New Findings on How Ketamine Prevents Depression
The discovery that the anaesthetic ketamine can help people with severe depression has raised hopes of finding new treatment options for the disease.
How Snakes Got Their Fangs
Ever wondered how deadly snakes evolved their fangs?