Helical nucleocapsids in infected cells are composed of Marburg viral genomic RNA and nucleoproteins, or NPs, that are structurally similar to those of the Ebola virus. Future drug development may be possible based on the targeting of nucleocapsid formation, which may inhibit the Marburg virus’ ability to replicate.
Tag: RNA structure
A fast, accurate system for quickly solving stubborn RNA structures from pond scum, the SARS-CoV-2 virus and more
Naked RNA molecules are too floppy for high-res 3D imaging, but a system developed at SLAC and Stanford fixes that. It reveals detailed RNA structures from a pond scum critter and COVID-19 virus.