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UrduReducing health disparities in incidence and mortality for major types of cancers can be aided by sophisticated computer modeling efforts, according to new, wide-ranging perspectives from researchers at Georgetown University’s Lombardi Comprehensive Cancer Center and colleagues around the country.
Tag: Cancer
AACI Congratulates Dr. Monica Bertagnolli on Confirmation as NIH Director
The Association of American Cancer Institutes (AACI) congratulates Monica Bertagnolli, MD, on her U.S. Senate confirmation today as the next director of the National Institutes of Health (NIH).
Improving the efficacy of cancer immunotherapy with modified CAR-T cells
CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful. A limiting factor of this otherwise very effective and safe therapy is that the cells used in the process quickly reach a state of exhaustion.
The challenges of cancer caregiving
As more cancer care is delivered in outpatient treatment centers such as Fred Hutchinson Cancer Center in Seattle, the burden on cancer caregivers is evolving. Fred Hutch has developed a package of stories to support and celebrate the role of caregivers in cancer care.
High biological age may increase the risk of dementia and stroke
People who have a higher biological age than their actual chronological age have an increased risk of stroke and dementia. The findings suggest that by slowing down the body’s aging processes, it may be possible to reduce or delay the onset of disease.
Mount Sinai Researchers Receive $7 Million to Improve Outcomes for High-risk Blood Cancer Patients From the Multiple Myeloma Research Foundation
The Mount Sinai Health System has received a $7 million grant from the Multiple Myeloma Research Foundation for a three-year project that aims to fast-track novel translational concepts to improve outcomes for people with high risk myeloma, the second most common blood cancer in the United States.
Case Western Reserve University School of Medicine launches Institute for Glial Sciences
Case Western Reserve University has established an Institute for Glial Sciences to advance research of glial cells and their critical role in the health and diseases of the nervous systems, including multiple sclerosis, Alzheimer’s, pediatric leukodystrophies, Autism spectrum disorders, Parkinson’s disease and cancer.
New NUS study provides insights into early breast cancer development in individuals with BRCA2 mutations
A pioneering study led by the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore and the University of Cambridge (UK) has uncovered vital insights into the distinct effects of BRCA2 mutations on breast tissue cells, shedding light on early breast cancer development in people with BRCA2 mutations.
Markey Cancer Center study provides valuable insights into drivers of cancer risk
As people age, the DNA in their cells begins to accumulate genetic mutations. Mosaic chromosomal alterations (mCAs), a category of mutations acquired in blood cells, are linked with a 10-fold increased risk of developing blood cancer. mCAs hold promise as a tool to identify people at high risk of developing certain cancers and diseases, but they have not yet been studied among a large, diverse cohort of people – a critical step required before such testing can be developed. University of Kentucky Markey Cancer Center researcher Yasminka A. Jakubek, Ph.D., has led the first large-scale effort to understand the co-occurrence of mCAs among individuals of diverse ancestries. The study was published in Nature Genetics Oct. 30.
American Cancer Society Updates Lung Cancer Screening Guideline: Nearly Five Million U.S. Adults who Smoke and Formerly Smoked Now Recommended for Testing
The American Cancer Society releasesan update of its lung cancer screening guideline to help reduce the number of people dying from the disease due to smoking history.
Cancer drug shows promise targeting genetic weakness in some tumors, comments Virginia Tech expert
In an invited commentary, Kathleen Mulvaney, assistant professor with the Fralin Biomedical Research Institute at VTC, talks about the potential of a new drug that has shown early promise in clinical trials for solid tumors by killing cancer cells that lack specific tumor suppressor genes.
High insulin levels directly linked to pancreatic cancer
First detailed explanation of why people with obesity and Type 2 diabetes are at an increased risk of pancreatic cancer
New Study Shows Insurance Coverage Disruptions Affect Key Cancer Screenings for U.S. Adults
A new study by researchers at the American Cancer Society shows that adults in the United States with prior insurance coverage disruptions are significantly less likely to receive guideline-concordant and past-year cancer screening, compared to people with continuous coverage.
New Study Shows Adults Treated for Non-Small Cell Lung Cancer Vulnerable to Hazards of Wildfires
New research by scientists at the American Cancer Society and the University of California, San Francisco, shows individuals in the United States undergoing radiotherapy for non-small cell lung cancer who are exposed to wildfires near the treating facility have worse overall survival than unexposed individuals.
New Study Finds Limited Documentation of Cost Discussions With Patients Newly Diagnosed With Advanced Cancer
A new study by researchers at the American Cancer Society and the National Cancer Institute, shows only about a quarter of individuals newly diagnosed with advanced cancers had documented physician discussions about costs of care, which may hinder identifying patient needs and tracking outcomes of referrals for assistance.
New Research Shows Patients Receiving Cancer Treatment Understand Health Insurance Basics; Important Knowledge Gaps Remain
A new study by researchers at the American Cancer Society showed among patients receiving outpatient cancer treatment in two sites, most people could understand basic health insurance terms, such as premiums and deductibles.
Scientists have discovered how extracellular structures affect the metastases of cancerous tumors
The dependence between biomechanical properties of extracellular matrix and the development of tumor cells inside it was proven by scientists. This will allow to create more realistic models for studying growth of cancer tumors and metastases.
Common chemotherapy drugs don’t work like doctors thought, with big implications for drug discovery
A new study from the University of Wisconsin–Madison suggests that chemotherapy may not be reaching its full potential, in part because researchers and doctors have long misunderstood how some of the most common cancer drugs actually ward off tumors.
Anti-anxiety drug may improve brain cancer survival chances
A new research study shows that cerebrospinal fluid reduces current treatment efficacy in brain cancer and identifies new therapeutic opportunities.
Novel small molecule 5D4 disrupts several molecular pathways, including MYC, that lead to cancer growth
Researchers at Baylor College of Medicine have identified a small molecule named 5D4 that can suppress the growth of breast and ovarian cancers in animal models.
Preventing collateral damage in cancer treatment
Using a simple concept and a patented Sandia sensor that detects radioactive materials, a team at Sandia National Laboratories has developed a patch to stop damage to healthy tissue during proton radiotherapy, one of the best tools to target certain cancerous tumors.
Researchers identify ‘switch’ to activate cancer cell death
A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die.
Highest risk patients with clear-cell renal cell carcinoma benefit from adjuvant everolimus
New study finds everolimus benefits high-risk kidney cancer patients
Does diabetes affect the survival of individuals with colorectal cancer?
Study reveals a link between complicated diabetes and a higher risk of death
MEDSIR presents the results of three new studies at ESMO 2023: LUPER, focusing on lung cancer, and two translational studies of PHERGain in breast cancer
MEDSIR, a company specializing in the strategic design of independent clinical research, today presented the results of three new studies at the European Society for Medical Oncology (ESMO 2023).
Adding Immunotherapy to Chemotherapy Regimen Improves Survival in Metastatic Bladder Cancer Patients
A clinical trial co-led by Mount Sinai researchers is the first to show that using chemotherapy with immunotherapy resulted in improved survival in patients with an advanced type of bladder cancer. The results were simultaneously reported in The New England Journal of Medicine and at the annual meeting of the European Society for Medical Oncology.
Dual-action drug produces positive results in patients with advanced neuroendocrine tumors, trial finds
Cabozantinib, which targets tumor cell growth and tumor blood vessel growth, sharply improved progression-free survival over placebo in patients with extra-pancreatic and pancreatic neuroendocrine tumors
A Cancer Survival Calculator Is Being Developed Using Artificial Intelligence
Researchers have developed an artificial intelligence (AI)–based tool for estimating a newly diagnosed cancer patient’s chances for surviving long term, according to a study presented at the American College of Surgeons (ACS) Clinical Congress 2023.
Perguntas e respostas da Mayo Clinic: Definição de câncer de cabeça e pescoço
Um colega de trabalho foi diagnosticado recentemente com câncer bucal depois que uma tosse incômoda o levou ao médico. Isso me fez pensar sobre a incidência de câncer de cabeça e pescoço e se eu deveria passar por uma triagem. Estou com pouco mais de 40 anos e procuro ficar atento para fazer um check-up anual.
Preguntas y respuestas de Mayo Clinic: definición del cáncer de cabeza y cuello
Un compañero de trabajo recientemente recibió un diagnóstico de cáncer de boca luego de que una tos molesta lo hiciera acudir al médico. Me quedé pensando en la incidencia del cáncer de cabeza y cuello y en los exámenes que se deben hacer para diagnosticarlo. Tengo un poco más de 40 años e intento tomar consciencia de la importancia del examen físico anual.
Shanghai Unveils Advanced Synchrotron-Based Proton Therapy Facility for Enhanced Cancer Treatment
Proton therapy is an advanced form of radiation therapy that uses protons instead of X-rays to treat cancer. Due to its precise nature, it significantly reduces damage to surrounding normal tissue. The Bragg peak of proton beams ensures that there’s almost no dose after the peak, protecting essential organs from unnecessary radiation.
Last Chance: Register in Advance for Media Credentials to Cover American College of Surgeons Clinical Congress 2023
Members of the media can still apply to cover the American College of Surgeons (ACS) Clinical Congress 2023.
New Cancer Therapy Target Stops Tumor Cells From Sharing Resources
Researchers at University of California San Diego have discovered a process in which liver cells share molecules in order to multiply under conditions that would ordinarily suppress cell proliferation. They also found evidence that this process occurs in various types of cancer cells.
A powerful new tool in the fight against one of the deadliest cancers
Researchers from Osaka University unveil a radioactive monoclonal antibody that can both diagnose and treat a deadly type of pancreatic cancer
New 3D-printed tumor model enables faster, less expensive and less painful cancer treatment
Researchers combining bioprinting with synthetic chips to understand tumors in 3D
RUDN Biochemists Found How to Weaken Cancer Cells
Biochemists from RUDN University described how to prevent cancer cells from becoming resistant to chemotherapy drugs. Having determined the resistance mechanism, biochemists selected a drug that can slow down it.
Tumor-destroying soundwaves receive FDA approval for liver treatment in humans
The U.S. Food and Drug Administration has approved the use of sound waves to break down tumors—a technique called histotripsy—in humans for liver treatment.
Engineered bacteria paint targets on tumors for cancer-killing T cells to see
Synthetic biologists at Columbia Engineering report today a new approach to attacking tumors. They have engineered tumor-colonizing bacteria (probiotics) to produce synthetic targets in tumors that direct CAR-T cells to destroy the newly highlighted cancer cells.
Association for Molecular Pathology Publishes Best Practice Recommendations for Liquid Biopsy Assay Validations
The Association for Molecular Pathology has published best practice recommendations for validating and reporting clinical circulating tumor DNA (ctDNA) or liquid biopsy assays and their related scientific publications.
Primary care reminder plus patient outreach intervention improved rates of follow-up after abnormal cancer test results
When cancer screening in a patient reveals an abnormal test result, prompt follow-up is critical so that further tests can be conducted, and if needed, treatment can be initiated as soon as possible. Numerous barriers to such follow-up exist, however.
Inflammatory Breast Cancer: Know the Risks and Warning Signs of This Rare, Fast-Growing Cancer
Inflammatory breast cancer is a rare type of breast cancer. It only accounts for one to five percent of all breast cancer cases, but it’s important to know your risk and the warning signs, as this form of the disease is aggressive, fast-growing, and hard to detect early. For October, during Breast Cancer Awareness Month, the American Cancer Society is highlighting IBC to help women be aware of this invasive cancer.
Thailand Hub of Talent for Cancer Immunotherapy International Conference
The Faculty of Medicine, Chulalongkorn University, cordially invites all to attend the “Thailand Hub of Talent for Cancer Immunotherapy International Conference: Portal to Global Collaboration for Next Generation Cell and Gene Therapy Development” on November 16-17, 2023 at Bhumisiri Mangklanusorn Building, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Dr. Deepa Masrani and Dr. Wen Liang are Featured Guests for the October 2023 edition of “Medoscopy”
Mercy’s breast health experts Dr. Deepa Masrani and Dr. Wen C. Liang are guests for the October 2023 edition of “Medoscopy”; October is National Breast Cancer Awareness Month.
Cleveland Clinic’s Timothy Chan, M.D., Ph.D., Elected To National Academy of Medicine
Timothy Chan, M.D., Ph.D., chair of Cleveland Clinic’s Global Center for Immunotherapy and Precision Immuno-Oncology and Sheikha Fatima Bint Mubarak Endowed Chair in Immunotherapy and Precision Immuno-Oncology, has been elected to the National Academy of Medicine (NAM), one of the highest honors in the fields of health and medicine.
New research led by Mays Cancer Center reveals how mutations in BRCA1 affect cancer susceptibility in women
Three decades after discoveries linking mutations in the BRCA1 gene to breast and ovarian cancer susceptibility, research led by Mays Cancer Center at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has pinpointed the molecular mechanism by which a large portion of these mutations cause cancers in women.
World-first research breakthrough sparks new hope for bowel cancer patients
Every year, over 15,500 Australians are diagnosed with bowel cancer, and it is the second leading cause of cancer deaths in the country. Over 1,700 (one in ten) of those diagnosed are young Australians aged under 50, and this incidence is increasing.
Ultrasensitive blood test detects ‘pan-cancer’ biomarker
Diagnostic tools for timely, accurate and inexpensive early cancer detection that can assess risk or monitor response to treatment could help patients get the care they need faster and improve existing care strategies.
Hackensack Meridian Health Research Institute Creates First Spin-off Company, EValuate Diagnostics
The company, based on science from the Hackensack Meridian Center for Discovery and Innovation, promises to capture biomarkers for early diagnostics detecting cancer and a variety of diseases.
Results: Study Explores Pre-Operative Radiation Boost for Breast Cancer Patients
New Brunswick, N.J., October 3, 2023 – For breast cancer patients undergoing a lumpectomy, a type of breast cancer surgery in which the tumor and a small amount of surrounding tissue called the margin is removed, the standard mode of treatment…
Tip Sheet: First Lady Jill Biden visits Fred Hutch, new center for Asian American, Native Hawaiian and Pacific Islander health studies — and health risks from loneliness
Below are summaries of recent Fred Hutchinson Cancer Center research findings and other news. October is Breast Cancer Awareness Month.