Nature Article Highlights UAMS Effort to Share COVID-19 Images on National Cancer Database

Data experts with the University of Arkansas for Medical Sciences (UAMS) have uploaded clinical images of COVID-19 patients to a publically available national database that scientists can use in researching the disease and its impact in a global pandemic.

Singing a Tumor Test Song

Singing may be the next-generation, noninvasive approach to determining the health of a patient’s thyroid. When a person sings, the vibrations create waves in the tissue near the vocal tract called shear waves. If a tumor is present in the thyroid, the elasticity of its surrounding tissue increases, stiffening, and causing the shear waves to accelerate. Using ultrasound imaging to measure these waves, researchers can determine the elasticity of the thyroid tissue. They demonstrate the technique in Applied Physics Letters.

Can Sodium-Ion Batteries Replace Trusty Lithium-Ion Ones?

Sodium-ion batteries are a potential replacement for lithium batteries, but different anodes are needed for the same level of performance. Amorphous carbon is known to be a useful anode, because it has defects and voids that can be used to store sodium ions. Nitrogen/phosphorus-doped carbon also offers appealing electrical properties. In Applied Physics Reviews, researchers describe how they applied basic physical concepts of atomic scale to build high-performance anodes for sodium-ion batteries.

Disposable Helmet Retains Cough Droplets, Minimizes Transmission to Dentists, Otolaryngologists

Dentists and otolaryngologists are at particular risk of infection of COVID-19, since they need direct access to the mouth, nose, and throat of patients. The current solutions are expensive, not highly effective, and not very accessible. In Physics of Fluids, researchers discuss their design of an open-faced helmet for patient use that is connected to a medical-grade air filtration pump from the top that creates a reverse flow of air to prevent cough droplets from exiting the helmet.

Wearable Electronics for Continuous Cardiac, Respiratory Monitoring

A small and inexpensive sensor, announced in Applied Physics Letters and based on an electrochemical system, could potentially be worn continuously by cardiac patients or others who require constant monitoring. A solution containing electrolyte substances is placed into a small circular cavity that is capped with a thin flexible diaphragm, allowing detection of subtle movements when placed on a patient’s chest. The authors suggest their sensor could be used for diagnosis of respiratory diseases.

How many tests after vasectomy? Guideline update leads to change in practice

A change in evidence-based guidelines for vasectomy may have led to a reduction in the number of follow-up tests to confirm the procedure was successful, reports a study in Urology Practice®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Green earplugs

Cars, trains, planes: For two thirds of the European population, traffic noise is part of everyday life. However, the right environment can have a major impact on this nuisance, as Empa researchers have found out. Green spaces in urban areas help to make road and railroad noise less of a nuisance. Only in the case of aircraft noise does this seem counterproductive: the greener the surroundings, the more disturbing the aircraft noise.

SARS-CoV-2 can infect neurons and damage brain tissue, study indicates

Using both mouse and human brain tissue, researchers at Yale School of Medicine have discovered that SARS-CoV-2 can directly infect the central nervous system and have begun to unravel some of the virus’s effects on brain cells. The study, published today in the Journal of Experimental Medicine (JEM), may help researchers develop treatments for the various neurological symptoms associated with COVID-19.

The Odd Structure of ORF8: Scientists Map the Coronavirus Protein Linked to Disease Severity

A team of biologists who banded together to support COVID-19 science determined the atomic structure of a coronavirus protein thought to help the pathogen evade and dampen response from human immune cells. The structural map has laid the groundwork for new antiviral treatments and enabled further investigations into how the newly emerged virus ravages the human body.

Study shows conflict between divorced parents can lead to mental health problems in children

A study from Arizona State University’s REACH Institute has found that when children are exposed to conflict between their divorced or separated parents, they experience fear of abandonment. This worry about being abandoned in response to interparental conflict was associated with future mental health problems in children, especially for children who had strong relationships with their fathers.

Protecting lungs from ventilator-induced injury

An unfortunate truth about using mechanical ventilation to save lives is that the pressure can cause further lung damage. Scientists are working to boost a natural cellular process in pursuit of a therapy that could lower the chances for lung damage in patients on ventilators.

Penn Medicine Surgeons Develop Universal Patient-Reported Outcomes Tool to Improve Hernia Care

Penn Medicine researchers have successfully developed, tested, and implemented a first-of-its-kind, patient-informed questionnaire tool for ventral hernia repair surgery patients that could be broadly used to improve the way clinicians care for patients and potentially outcomes.

UCI scientists measure local vibrational modes at individual crystalline faults

Irvine, Calif., Jan. 11, 2021 – Often admired for their flawless appearance to the naked eye, crystals can have defects at the nanometer scale, and these imperfections may affect the thermal and heat transport properties of crystalline materials used in a variety of high-technology devices. Employing newly developed electron microscopy techniques, researchers at the University of California, Irvine and other institutions have, for the first time, measured the spectra of phonons – quantum mechanical vibrations in a lattice – at individual crystalline faults, and they discovered the propagation of phonons near the flaws.

Rotten Egg Gas Could Guard Against Alzheimer’s Disease

Typically characterized as poisonous, corrosive and smelling of rotten eggs, hydrogen sulfide’s reputation may soon get a face-lift thanks to Johns Hopkins Medicine researchers. In experiments in mice, researchers have shown the foul-smelling gas may help protect aging brain cells against Alzheimer’s disease. The discovery of the biochemical reactions that make this possible opens doors to the development of new drugs to combat neurodegenerative disease.

High levels of distress and burnout identified among clinicians at leading cardiac centre

More than half the clinicians surveyed at the Peter Munk Cardiac Centre reported burnout and high levels of distress according to a series of studies published today in the Canadian Medical Association Journal Open (CMAJ-OPEN). In these studies carried out before the COVID-19 pandemic, 78% of nurses, 73% of allied health staff and 65% of physicians described experiencing burnout.

Enhanced Oral Uptake of Exosomes Opens Cell Therapy Alternative

Cell-derived exosomes are effective in treating disease when mixed with the dominant protein in breast milk and given orally, a new Smidt Heart Institute study of laboratory mice shows. The findings, published in the peer-reviewed Journal of Extracellular Vesicles, could help develop new oral medications for treating patients with muscular dystrophy and heart failure.

New climate change study: Number of people suffering extreme droughts will double

Michigan State University is leading a global research effort to offer the first worldwide view of how climate change could affect water availability and drought severity in the decades to come.

By the late 21st century, global land area and population facing extreme droughts could more than double — increasing from 3% during 1976-2005 to 7%-8%, according to Yadu Pokhrel, associate professor of civil and environmental engineering in MSU’s College of Engineering, and lead author of the research published in Nature Climate Change.

Study shows tweaking one layer of atoms on a catalyst’s surface can make it work better

When an LNO catalyst with a nickel-rich surface carries out a water-splitting reaction, its surface atoms rearrange from a cubic to a hexagonal pattern and its efficiency doubles. Deliberately engineering the surface to take advantage of this phenomenon offers a way to design better catalysts.

Wistar Scientists Discover Link Between a Genetic Driver of Ovarian Cancer and Metabolism, Opening the Way for New Therapeutic Strategies

Wistar scientists found mutations that inactivate the ARID1A gene in ovarian cancer increase utilization of the glutamine amino acid making cancer cells dependent on glutamine metabolism. Researchers also showed that pharmacologic inhibition of glutamine metabolism may represent an effective therapeutic strategy for ARID1A-mutant ovarian cancer.