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UrduArticle title: Genomic and epigenomic responses to aspirin in human colonic organoids Authors: David Witonsky, Margaret C. Bielski, Jinchao Li, Kristi M. Lawrence, Ishmael N. Mendoza, Hina Usman, Sonia S. Kupfer From the authors: “This is the first study to…
Month: March 2023
Microvascular Impairment Caused by Chronic Estrogen Exposure Is Sex-specific
Article title: 17β-estradiol promotes sex-specific dysfunction in isolated human arterioles Authors: Gopika SenthilKumar, Boran Katunaric, Henry Bordas-Murphy, Micaela Young, Erin L. Doren, Mary E. Schulz, Michael E. Widlansky, Julie K. Freed From the authors: “To our knowledge, this is the…
Study Explores How Pressure in the Skull Affects Brain Blood Flow after Brain Injury
Article title: Contribution of intracranial pressure to human dynamic cerebral autoregulation after acute brain injury Authors: Sérgio Brasil, Ricardo C. Nogueira, Angela S. M. Salinet, Márcia H. Yoshikawa, Manoel J. Teixeira, Wellingson Paiva, Luiz M. S. Malbouisson, Edson Bor-Seng-Shu, Ronney…
U.S. birds’ Eastern, Western behavior patterns are polar opposites
Avian functional diversity patterns in the Western U.S., where species and functional richness are both highest during the breeding season, are the polar opposite of what is seen in the East, where functional diversity is lowest when species richness is high, according to new research.
Researchers ID Protein Crucial to Lung Endothelial Function, Could Lead to Targeted Treatment for Fibrosis
Article title: The matricellular protein CCN3 supports lung endothelial homeostasis and function Authors: Kalpana R. Betageri, Patrick A. Link, Andrew J. Haak, Giovanni Ligresti, Daniel J. Tschumperlin, Nunzia Caporarello From the authors: “Altogether, our results demonstrate that the matricellular protein…
Women with Obesity and Type 2 Diabetes May Improve Vascular Insulin Resistance through Weight Loss
Article title: Impact of sex and diet-induced weight loss on vascular insulin sensitivity in type 2 diabetes Authors: Camila Manrique-Acevedo, Rogerio Nogueira Soares, James A. Smith, Lauren K. Park, Katherine Burr, Francisco I. Ramirez-Perez, Neil J. McMillan, Larissa Ferreira-Santos, Neekun…
Kids with Cerebral Palsy Have More Small Muscle Fibers, More Stem Cells in Contractured Muscles
Article title: Resident muscle stem myogenic characteristics in postnatal muscle growth impairments in children with cerebral palsy Authors: Ryan E. Kahn, Timothy Krater, Jill E. Larson, Marysol Encarnacion, Tasos Karakostas, Neeraj M. Patel, Vineeta T Swaroop, Sudarshan Dayanidhi From the…
Using light to connect molecules
One study, led by the Toker group from Bar-Ilan University in Israel, observed peptide bond formation in clusters containing four serine dipeptides that were heated up by collisions. However, they found no evidence for the same process occurring in serine clusters. In that work they concluded that if two serine molecules can bind together to form a dipeptide, then the next stages of polymerization could probably occur readily.
Pesquisadores da Mayo Clinic relacionam o câncer de ovário com a colonização de bactérias no microbioma
Uma colonização específica de micróbios no trato reprodutivo é comumente encontrada em mulheres com câncer de ovário de acordo com um novo estudo do Centro de Medicina Individualizada da Mayo Clinic. A descoberta, publicada na revista Scientific Reports, fortalece a evidência de que o componente bacteriano do microbioma (uma comunidade de microrganismos que também consistem em vírus, leveduras e fungos) é um importante indicador para detecção precoce, diagnóstico e prognóstico do câncer de ovário.
باحثون من مايو كلينك يربطون بين سرطان المبيض وتكاثر عدد البكتيريا في الحَيُّوم الدقيق
عادة ما يوجد تكاثر لنوع معين من الميكروبات في الجهاز التناسلي للنساء المصابات يسرطان المبيض، وفقًا لدراسة جديدة من مركز مايو كلينك لنهج الطب الشخصي. إن هذا الاكتشاف المنشور في مجلة التقارير العلمية يقوي الأدلة التي تشير إلى أن المكون البكتيري للحَيُّوم الدقيق – وهو مجتمع من الكائنات الحية الدقيقة يتكون أيضًا من فيروسات وخمائر وفطريات – من المؤشرات الهامة للكشف المبكر عن سرطان المبيض وتشخيصه والتنبؤ بسير المرض.
Los investigadores de Mayo Clinic vinculan el cáncer de ovario con la colonización bacteriana en el microbioma
Según un nuevo estudio del Centro de Medicina Personalizada en Mayo Clinic, se suele hallar una colonización específica de microbios en el aparato reproductor de las mujeres con cáncer de ovario. Este descubrimiento, publicado en la revista Scientific Reports, refuerza las pruebas de que el componente bacteriano del microbioma (una comunidad de microorganismos que incluye virus, hongos y levaduras) es un indicador importante para la detección temprana, el diagnóstico y el pronóstico del cáncer de ovario.
Children’s Hospital Los Angeles Develops Liquid Biopsy Test for Pediatric Solid Tumors
CHLA researchers launched a liquid biopsy blood test to detect and differentiate between various pediatric cancers less invasively than a tissue biopsy.
Children and researchers envision a sustainable world
What might life in a circular economy look like? Empa and the St. Gallen University of Teacher Education (PHSG) are collaborating with gifted children to develop visions for a sustainable future and to compile them into an illustrated children’s book. The visions will combine the creativity of children with the expert knowledge of researchers.
Economics expert explains how consumer price reports show ‘inflation is not done yet’
Expectations that inflation has eased fueled recent stock market gains, but results from two major price-tracking indexes came in higher than expected, dousing that optimism with cold water. The statistics from these reports have economists predicting that the Federal Reserve will continue to raise interest rates to get inflation under control.
Out-of-this-world salad created for astronauts
An international team of scientists has created a salad that contains ingredients that could be grown on spacecraft and provide optimum nutrition for astronauts heading into deep space.
Social workers experienced depression, PTSD, and anxiety at alarming rates during pandemic
A new study published in the journal International Social Work has uncovered concerning rates of depression, post-traumatic stress disorder (PTSD) and anxiety among social workers.
Pharma Industry Consortium Completes Brain Wave Study of Ketamine Effects on Healthy Volunteers
The ERP Biomarker Qualification Consortium announced today the successful completion of a pharma industry-sponsored study to measure the electrophysiologic effects of ketamine on healthy brain function.
Endocrine Society applauds Eli Lilly’s efforts to lower insulin costs
The Endocrine Society commends Eli Lilly and Company for taking steps to reduce insulin prices and make insulin affordable for more people with diabetes.
Neoadjuvant immunotherapy improves outlook in high-risk melanoma
Patients with high-risk melanoma who received the immunotherapy drug pembrolizumab both before and after surgery to remove cancerous tissue had a significantly lower risk of their cancer recurring than similar patients who received the drug only after surgery.
Neoadjuvant Pembrolizumab Administered Before Surgery Improves Outcomes of Melanoma Patients
A team of researchers from institutions across the United States, including Moffitt Cancer Center, launched a phase 2 clinical trial evaluating a new treatment option for this patient population. Their results, published in The New England Journal of Medicine, show that treating resectable stage 3 and 4 melanoma patients with the immunotherapy drug pembrolizumab both before and after surgery greatly improves outcomes when compared to pembrolizumab given only after surgery.
SNAP reductions ‘could exacerbate an already challenging situation’
Pandemic-related boosts in the Supplemental Nutritional Assistance Program (SNAP) will end today across the country for millions of Americans. Angela Odoms-Young, a nutritional sciences professor of at Cornell University whose research focuses on health outcomes in low-income populations, says that…
Solid‒gas carbonate formation during dust events on Mars
A joint research team led by Dr. Xiaohui Fu and Dr. Zhongchen Wu from Shandong University, China, proposed a new carbonate formation mechanism in Martian dust activities based on simulation experimental studies.
Eli Lilly ‘just the first shoe to drop’ in drug cost changes
Drugmaker Eli Lilly and Company announced it would significantly reduce the prices of several of its insulin products and cap patient insulin out-of-pocket costs at $35 per month. Nick Fabrizio, professor of health policy at Cornell University, says this is…
Brain Injuries Drop 20% for Babies with Heart Defects
Recent advances in newborn heart surgery have greatly reduced brain injuries in infants with congenital heart disease, according to a 20-year study by scientists at UCSF Benioff Children’s Hospitals and British Columbia Children’s Hospital (BCCH).
Beezin’: The dangerous TikTok trend involving Burt’s Bees
Why putting lip balm on eyelids is bad for your eyes
Three Penn Medicine Faculty Members Named Hastings Center Fellows
Three faculty from the Perelman School of Medicine at the University of Pennsylvania have been named 2023 Hastings Center Fellows. Emily Largent, PhD, RN, Peter Reese, MD, PhD, and Dominic Sisti, PhD, are among 12 new Fellows joining an elected group of over 200.
Children’s Hospital Los Angeles Launches Eighth Annual Make March Matter® Fundraising Campaign
Children’s Hospital Los Angeles (CHLA) launched its eighth annual Make March Matter campaign Wednesday with actress and longtime CHLA supporter Jamie Lee Curtis.
High Blood Pressure During Pregnancy Linked to Thinking Problems Later
High blood pressure disorders during pregnancy are associated with an increased risk of thinking problems later in life, according to a study published in the March 1, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Can Mediterranean Diet Help People with MS Preserve Thinking Skills?
People with multiple sclerosis (MS) who follow a Mediterranean diet may have a lower risk for problems with memory and thinking skills than those who do not follow the diet, according to a preliminary study released today, March 1, 2023, that will be presented at the American Academy of Neurology’s 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023.
Tracking Trash: Researchers use aerial imaging to capture rapidly changing hurricane debris data
Juyeong Choi, an assistant professor in the Department of Civil and Environmental Engineering in the FAMU-FSU College of Engineering, will lead a $75,000 National Science Foundation-funded study examining debris collection and illegal dumping in the aftermath of Hurricane Ian, a Category 4 storm that hit southwestern Florida in 2022.
Researchers Examine Career Confidence in Underrepresented Biomedical Scientist Trainees
After polling 6,000 graduate and postdoctoral respondents across 17 US institutions, researchers found that self-efficacy was generally lower than anticipated, particularly among those with higher levels of expertise and experience. Their results were recently published in the journal PLOS ONE.
Happy birthday to Dr. Seuss: FSU literacy researcher offers tips to get kids reading
By: Kathleen Haughney | Published: March 1, 2023 | 2:52 pm | SHARE: With school-aged children celebrating the joy of reading through Read Across America Day or Dr. Seuss Day this week, many parents and teachers are capitalizing on that joy to remind kids of the power of a good book. Florida State University Assistant Professor Lakeisha Johnson, a faculty affiliate for The Florida Center for Reading Research, has assembled a tip sheet for parents using this time to encourage their children to read more.
Supernova From the Year 185: A Rare View of the Entirety of This Supernova Remnant
The tattered shell of the first-ever historically recorded supernova was captured by the US Department of Energy-fabricated Dark Energy Camera, which is mounted on the National Science Foundation’s (NSF) Víctor M. Blanco 4-meter Telescope at Cerro Tololo Inter-American Observatory in Chile, a Program of NSF’s NOIRLab. RCW 86’s ring of debris is all that remains of a white-dwarf star that exploded more than 1800 years ago, when it was recorded by Chinese stargazers as a ‘guest star’.
Cerro Tololo logra un retrato único de una supernova que explotó hace más de 1.800 años
La Cámara de Energía Oscura, fabricada por el Departamento de Energía de EE.UU e instalada en el Telescopio de 4 metros Víctor M. Blanco de la Fundación Nacional de Ciencias (NSF por sus siglas en inglés) de EE.UU en el Observatorio Interamericano Cerro Tololo (Chile), un Programa de NOIRLab de NSF y el Observatorio AURA, captó los vestigios de la primera supernova registrada en la historia. El anillo de escombros de RCW 86 es todo lo que queda de una estrella enana blanca que explotó hace más de 1.800 años, cuando fue registrada por los astrónomos chinos como una “estrella invitada”.
Impact of racism and inequities on African Americans’ sleep and well-being
UCI professor of environmental and occupational health, Karen Lincoln, PhD, shares her expertise in health disparities affecting African Americans built upon the lived experience as an African American woman and through her interdisciplinary training at the Program for Research on African…
Poor sleep exacerbates the development of multiple chronic diseases among Chinese and Korean Americans
Brittany Morey, PhD, assistant professor of health, society, and behavior at UCI’s Program in Public Health is dedicating her career to closing the gap of missing knowledge and data around health disparities impacting Asian Americans, Native Hawaiians and Pacific Islanders. …
Gut bacteria are crucial for liver repair
When parts of the liver are removed, the body can replace the missing tissue.
Glacier National Park could provide climate haven for Canada Lynx
Glacier National Park is home to around 50 Canada lynx, more than expected, surprising scientists who recently conducted the first parkwide occupancy survey for the North American cat.
Harvard Medical School Media Immersion: Boston, June 8-9, 2023
Application deadline: March 31
Biden taps Sandia Labs’ senior leader for quantum advisory committee
Deborah Frincke, associate laboratories director of national security programs at Sandia National Laboratories, has been appointed to the National Quantum Initiative Advisory Committee.
Study forecasts tile drainage and crop rotation changes for nitrogen loss
Midwestern agriculture contributes the vast majority of nitrogen in the Gulf of Mexico, causing an oxygen-starved hypoxic zone and challenging coastal economies. State and federal policies have tried for decades to provide solutions and incentives, but the hypoxic zone keeps coming back.
Review of studies finds disparity in presumptive chlamydia and gonorrhea treatment rates despite CDC guidelines
A Regenstrief Institute-led review of studies on proactive health services for chlamydia and gonorrhea has found that rates of presumptive treatment — antibiotics prior to laboratory test confirmation — varies widely.
Tracking data reveals how seabird species adopt different strategies to cope with extreme storms
Researchers at the Max Planck Institute of Animal Behavior in Germany and Swansea University have revealed how different seabird species use distinct strategies to cope with cyclones, with some flying directly into the storm, and others using avoidance tactics.
FSU criminology faculty ranked No. 1 in the nation for research productivity and scholarly influence
Faculty in Florida State University’s College of Criminology and Criminal Justice are No. 1 in the country for research productivity and influence among faculty in their field, according to a quantitative assessment in the Journal of Criminal Justice Education. The journal’s findings draw from data gathered from criminology and criminal justice doctoral programs in the United States from 2015-2021.
Study: Seizures can be predicted more than 30 minutes before onset in patients with temporal lobe epilepsy
Seizures can be predicted more than 30 minutes before onset in patients with temporal lobe epilepsy, opening the door to a therapy using electrodes that could be activated to prevent seizures from happening, according to new research from UTHealth Houston.
Taking vitamin D could help prevent dementia, study finds
Researchers at the University of Calgary’s Hotchkiss Brain Institute in Canada and the University of Exeter in the UK explored the relationship between vitamin D supplementation and dementia in more than 12,388 participants of the US National Alzheimer’s Coordinating Center, who had a mean age of 71 and were dementia-free when they signed up.
Dutch healthcare system isn’t prepared for pregnant transgender men
Transgender men can, and often wish to, become pregnant. However, they do need extra guidance and care providers often lack the necessary knowledge and skills.
Moose can play a big role in global warming
One of the biggest potential single sources of carbon emissions from wooded parts of Norway has four legs, weighs as much as 400-550 kg and has antlers.
Global Efforts to Eliminate Mercury Skin Lightening Products
Led by the UN Environment Programme (UNEP), with funding from the Global Environment Facility, and executed by the World Health Organization (WHO) and Biodiversity Research Institute (BRI), the Eliminating mercury skin lightening products project will work to reduce the risk of exposure to mercury-added skin lightening products, raising awareness of the health risks associated with their use, developing model regulations to reduce their circulation, and halting production, trade, and distribution across domestic and international markets.
‘China’s menacing behavior,’ military buildup cause for concern
China’s aggression and increasingly provocative actions in the Indo-Pacific reflect its willingness to openly challenge the U.S.-led economic order in the growth-oriented region, according to a University of Miami China and defense expert.