Johns Hopkins Medicine researchers report that new experiments with genetically engineered mice have found clear connections among a range of autism types and abnormalities in brain cells whose chemical output forges platonic (non-sexual) feelings of love and sociability.
Month: October 2020
Research Video News Brief: Projecting the Potential Impact of COVID-19 School Closures on Academic Achievement
A study published today in Educational Researcher, a peer-reviewed journal of the American Educational Research Association, provides preliminary projections of the impact of COVID-19-related school closures in spring 2020 on student learning. The study authors found that compared to a typical year, students likely did not gain as much academically during the truncated 2019–20 school year and likely lost more of those gains due to extended time out of school.
Trump Supporters Increasingly Less Likely to Trust Health Officials, Survey Finds
President Trump’s supporters and opponents are increasingly at odds over the coronavirus pandemic, according to a new survey led by researchers from Rutgers University–New Brunswick and University of California-Berkley.
Predictive Model Reveals Function of Promising Energy Harvester Device
A small energy harvesting device that can transform subtle mechanical vibrations into electrical energy could be used to power wireless sensors and actuators for use in anything from temperature and occupancy monitoring in smart environments, to biosensing within the human body. In research recently published in the Journal of Micromechanics and Microengineering, engineers at Rensselaer Polytechnic Institute developed a predictive model for such a device, which will allow researchers to better understand and optimize its functionalities.
CHOP Genomic Study Reveals Role for Hypothalamus in Inflammatory Bowel Disease
Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies (GWAS), researchers at Children’s Hospital of Philadelphia (CHOP) have found significant genetic correlations between inflammatory bowel disease (IBD) and stress and depression. The researchers went on to implicate new genes involved in IBD risk that are enriched in both derived hypothalamic neurons, from a part of the brain that has a vital role in controlling stress and depression, and organoids derived from colon cells, a region more commonly studied in the context of IBD.
Accelerating the Development of New Medicines
Five research projects with exceptional promise to deliver new life-changing and health-altering therapies have received the inaugural Blavatnik Therapeutics Challenge Awards (BTCA) at Harvard Medical School.
POSITIVE STUDENT-TEACHER RELATIONSHIPS BENEFIT STUDENTS’ LONG-TERM HEALTH, STUDY FINDS
Teens who have good, supportive relationships with their teachers enjoy better health as adults, according to research published by the American Psychological Association.
New analysis reveals ‘long-hauler’ COVID-19 patients with prolonged skin symptoms
Analysis of the largest registry of COVID-19 patients with dermatological symptoms has revealed a subset of patients, called ‘long-haulers’ or ‘long COVID’, who experience prolonged symptoms (lasting >60 days) on their skin.
Sensors driven by machine learning sniff-out gas leaks fast
A new study confirms the success of a natural-gas leak-detection tool pioneered by Los Alamos National Laboratory scientists that uses sensors and machine learning to locate leak points at oil and gas fields, promising new automatic, affordable sampling across vast natural gas infrastructure.
Study Sheds Light on Critically Endangered Beluga Whale Population
A study recently published in Animal Microbiome outlines important first steps in understanding epidermal microbial communities in beluga whales, as well as their role in beluga health.
NUS researchers develop novel process that turns branches and prawn shells into nutritional supplements and medicine
Researchers from NUS Engineering have developed a novel conversion approach that marries chemical and biological processes to produce high-value amino acids such as L-DOPA and L-Proline from low-cost, abundant waste material like crustacean shells and sawdust.
Webinar: Carbon Transition Risk
UBS Quant Insight Series 2020, co-hosted by Maryland Smith, continues with a focus on climate change as a risk-management issue for investors.
$39 Million to better integrate renewables into power grid
The National Science Foundation has awarded $39 million to a team of engineers and computer scientists at the University of California San Diego to build a first-of-its-kind testbed to better understand how to integrate distributed energy sources such as solar panels, wind turbines, smart buildings and electric vehicle batteries into the power grid. The goal is to make the testbed available to outside research teams and industry by 2025.
Remdesivir for COVID-19: FDA Approved but Still Unproven
In a review of evidence from the most reliable data from randomized trials to find likely small-to-moderate effects of remdesivir, researchers say that totality of evidence compiled before the WHO trial results justifies compassionate use of remdesivir for severely ill patients. A smaller trial in China showed significantly decreased mean recovery time but no suggestion of a mortality benefit. ACTT-1 found the same mean recovery time and a suggestion of a mortality benefit that did not achieve statistical significance.
Boo! How Do Mexican Cavefish Escape Predators?
When startled, do all fish respond the same way? A few fish, like Mexican cavefish, have evolved in unique environments without any predators. To see how this lack of predation impacts escape responses that are highly stereotyped across fish species, scientists explored this tiny fish to determine if there are evolved differences in them. Findings reveal that the dramatic ecological differences between cave and river environments contribute to differences in escape behavior in blind cavefish and river-dwelling surface cavefish.
Argonne postdoctoral researcher Daniel Moberg wins Cozzarelli Prize
Argonne researcher Daniel Moberg has won a 2019 Cozzarelli Prize, awarded to the top scientific papers published in the Proceedings of the National Academy of Sciences.
Cut chores and kill chill time: new advice to boost children’s academic achievement
Determining a child’s best daily balance of sleep, activity and relaxation can be a challenge, but if you’re hoping to improve their academic results, then it’s time to cut back on chores and chill time, according to new research from the University of South Australia.
Cancer-Fighting Gene Restrains ‘Jumping Genes’
DALLAS – Oct. 29, 2020 – About half of all tumors have mutations of the gene p53, normally responsible for warding off cancer. Now, UT Southwestern scientists have discovered a new role for p53 in its fight against tumors: preventing retrotransposons, or “jumping genes,” from hopping around the human genome. In cells with missing or mutated p53, the team found, retrotransposons move and multiply more than usual. The finding could lead to new ways of detecting or treating cancers with p53 mutations.
Study Reveals Robust Performance in Aged Detonator Explosive
In a large, statistically significant, one-of-a-kind study, researchers at Los Alamos National Laboratory have confirmed that the explosive called PETN (Pentaerythritol tetranitrate), stabilized with a polysaccharide coating, is resistant to changes in particle shape, size, and structure that can degrade detonator performance over time.
Hackensack Meridian Health’s Tackle Kids Cancer Celebrates Five Years of Support to Fight Pediatric Cancer and Raises more than $10 Million
Philanthropic initiative of the Children’s Cancer Institute, reaches five year milestone combatting pediatric cancer
Un estudio descubre que los estadounidenses no conocen los síntomas y los riesgos de la retinopatía diabética
La retinopatía diabética es la causa más común de ceguera en los adultos de edad laboral; sin embargo, la mayoría de los estadounidenses de más de 40 años no conocen sus síntomas ni los factores de riesgo para esta afección común que amenaza la vista, según una encuesta encomendada por la Sociedad Estadounidense de Especialistas en Retina (American Society of Retina Specialists, ASRS).
Americans in the Dark on Diabetic Retinopathy Symptoms, Risks, Survey Finds
Diabetic retinopathy is the leading cause of blindness among working-age adults, yet most Americans over 40 don’t know its symptoms or the risk factors for this common sight-threatening condition, according to a survey commissioned by the American Society of Retina Specialists (ASRS).
How Did Red Algae Survive in Extreme Environments?
Red algae have persisted in hot springs and surrounding rocks for about 1 billion years. Now, a Rutgers-led team will investigate why these single-celled extremists have thrived in harsh environments – research that could benefit environmental cleanups and the production of biofuels and other products.
Towards next-generation molecule-based magnets
Magnets are to be found everywhere in our daily lives, whether in satellites, telephones or on fridge doors. However, they are made up of heavy inorganic materials whose component elements are, in some cases, of limited availability. Now, researchers from…
CHOP genomic study reveals role for hypothalamus in inflammatory bowel disease
Integrating 3D genomics with publicly available, genome-wide genetic data, researchers uncovered genetic correlations between IBD, stress, and depression
Where were Jupiter and Saturn born?
An additional planet between Saturn and Uranus was kicked out of the Solar System in its infancy
Brain imaging of tau protein in patients with various forms of dementia
A new imaging-based method could enable the early detection and differentiation of a wide variety of neurodegenerative disorders characterized by the buildup of tau protein in the brain, suggests a study published October 29 in the journal Neuron . The…
How octopus suckers “taste by touch”
Imagine if you could taste something simply by touching it. Octopuses can do just that with their unique “touch-taste” sense, made possible by the suction-cup-like suckers along each of their eight arms. Now, researchers reporting October 29 in the journal…
These spiders can hear
Ogre-faced spiders, named for their massive eyes, hide during the day and hunt by night, dangling from Florida palm fronds and casting silk nets on insects on the ground and in the air. In addition to their incredible night vision,…
Buzz kill: Ogre-faced spiders ‘hear’ airborne prey with their legs
ITHACA, N.Y. – In the dark of night, ogre-faced spiders with dominating big eyes dangle from a silk frame to cast a web and capture their ground prey. But these spiders also can capture insects flying behind them with precision,…
Study identifies pitfall for correcting mutations in human embryos with CRISPR
In a paper published today in the journal Cell , scientists describe unexpected, undesirable outcomes after editing genes in human embryos with CRISPR, a genomic editing system. The study, the most detailed analysis to date of CRISPR in human embryos,…
Breakthrough quantum-dot transistors create a flexible alternative to conventional electronics
Quantum dot logic circuits provide the long-sought building blocks for innovative devices, including printable electronics, flexible displays, and medical diagnostics
Hybrid photoactive perovskites imaged with atomic resolution for the first-time
A huge step towards better performing solar cells – a collaboration identified information previously invisible using Diamond’s ePSIC facility and microscopes of Oxford University’s Departments of Materials and Physics
Resistance and challenges to Green Deals should not be underestimated
EASAC Perspective on Transformative Change
Groundbreaking study on trained immunity to fight cancer
Huge collaborative effort led by TU/e researcher Prof. Willem Mulder develops nanomaterials to help body’s immune system fight cancer
Tube-dwelling anemone toxins have pharmacological potential, mapping study shows
Analysis identified 525 genes encoding proteins that act on the nervous system, cardiovascular system and cell walls. One of the molecules proved effective against cancer cells in preliminary test results
Streetlights contribute less to nighttime light emissions in cities than expected
The combination of smart city lighting and satellite imagery allows measurements of the contribution of street lights to urban lighting for the first time, and gives new hints for how to fight light pollution
PFAS: these “forever chemicals” are highly toxic, under-studied, and largely unregulated
Research presented at the 2020 GSA Annual Meeting
High rate of symptomless COVID-19 infection among grocery store workers
Those in customer-facing roles 5 times as likely to test positive as their colleagues
New Denisovan DNA expands diversity, history of species
While the continents of Africa and Europe have been obvious and fruitful treasure troves for exploration and discovery of our modern human origins, Asia has been somewhat overlooked. Scientists have thought that modern humans left Africa about 60,000 years ago…
Fungal species naturally suppresses cyst nematodes responsible for major sugar beet losses
The plant pathogenic nematode Heterodera schachtii infects more than 200 different plants, including sugar beets, and causes significant economic losses. Over the past 50 years, the primary management tool in California has been crop rotation. When the number of H.…
Researchers take a stand on algorithm design for job centers: Landing a job isn’t always the right goal
Imagine that you are a job consultant. You are sitting across from your client, an unemployed individual. After locating them in the system, up pops the following text on the computer screen; ‘increased risk of long-term unemployment’. Such assessments are…
Muscle pain and energy-rich blood: Cholesterol medicine affects the organs differently
600,000 Danes take medicine containing statins. Statins lower the cholesterol level and thus helps prevent cardiovascular disease and blood clots. But there is a different side to the coin. Treatment with statins may also have negative side effects, some of…
Why people with dementia go missing
People with dementia are more likely to go missing in areas where road networks are dense, complicated and disordered – according to new research from the University of East Anglia. Researchers studied hundreds of ‘missing person’ police reports for people…
Brainstem neurons control both behaviour and misbehaviour
A recent study at the University of Helsinki reveals how gene control mechanisms define the identity of developing neurons in the brainstem. The researchers also showed that a failure in differentiation of the brainstem neurons leads to behavioural abnormalities, including…
Decadeslong effort revives ancient oak woodland
CHAMPAIGN, Ill. — Vestal Grove in the Somme Prairie Grove forest preserve in Cook County, Illinois, looks nothing like the scrubby, buckthorn-choked tangle that confronted restoration ecologists 37 years ago. Thanks to the efforts of a dedicated team that focused…
Knee OA guidance for clinicians simplified and streamlined
The burden of knee osteoarthritis is set to continue to increase around the world. Ageing populations and rising levels of obesity, combined with an absence of a cure for the disease, will lead to an increased strain on health-care systems.…
Cancer-fighting gene restrains ‘jumping genes’
Finding sheds light on why mutations of the gene p53 are associated with cancer and could lead to new diagnostics or treatments
New ancient genomes reveal a complex common history of dogs and humans
Newly sequenced whole genomes of ancient dogs reveal a complicated genetic legacy that reflects a long, shared history with humans spanning more than 11,000 years into the past. “The dog is the oldest domesticated animal and has a very long…
New assay screens human brain organoids, doubles known candidate genes for microcephaly
A new tissue screening assay for human cerebral organoids identified 25 additional candidate genes for microcephaly, nearly doubling the number of currently known genes linked to the rare neurological condition. Some of these newly identified genes were associated with pathways…