Research shows fatty liver disease endangers brain health

In a study examining the link between non-alcoholic fatty liver disease (NAFLD) and brain dysfunction, scientists at the Roger Williams Institute of Hepatology, affiliated to King’s College London and the University of Lausanne, found an accumulation of fat in the liver causes a decrease in oxygen to the brain and inflammation to brain tissue – both of which have been proven to lead to the onset of severe brain diseases.

UNC Health Provider Ushers in First FDA-Approved Medication for Eosinophilic Esophagitis

Eosinophilic esophagitis (EoE) is an allergic condition of the esophagus that is on the rise throughout the United States. Patients with the condition typically have inflammation throughout their esophagus and trouble swallowing food – known as dysphagia.Without proper treatment, the lining of the esophagus becomes fibrous, and the passage becomes so narrowed, or strictured, that food can lodge in the esophagus, requiring medical attention.

Mediterranean Diet Linked to Lower Preeclampsia Risk

In a new study evaluating the Mediterranean diet and adverse pregnancy outcomes, investigators from the Smidt Heart Institute at Cedars-Sinai found that women who conceived while adhering to the anti-inflammatory diet had a significantly lower risk of developing preeclampsia during pregnancy.

A year in review: Argonne’s breakthroughs in 2022

Argonne researchers put their stamp on 2022 with accomplishments as varied as quantum science, wearable medical sensors, and climate change resilience and recovery.

Media Tip: Scientists use Argonne accelerator to study star-like environment created during National Ignition Facility laser shots

The recent achievement of fusion ignition at the National Ignition Facility (NIF) marks a monumental scientific step in controlling the physics involved in the quest for future limitless clean energy.

NIH researchers use 3D bioprinting to create eye tissue

Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases. The research team from the National Eye Institute (NEI), part of the National Institutes of Health, printed a combination of cells that form the outer blood-retina barrier—eye tissue that supports the retina’s light-sensing photoreceptors. The technique provides a theoretically unlimited supply of patient-derived tissue to study degenerative retinal diseases such as age-related macular degeneration (AMD).

Love is in the Air: College Couple Gets Engaged at Fall 2022 Commencement

Commencement is a time when new college graduates celebrate with their loved ones and look to the future as they start the next chapter of their lives. One UA Little Rock graduate celebrated another milestone in life by popping the question to his high school sweetheart and fellow UA Little Rock student who, of course, said yes!

Found! Lost Puzzle Piece Involved in Gene Regulation Revealed in Search That Began in Water-Loving, One-Celled Organism

After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain tumors, blood cancers and Kleefstra syndrome — a rare genetic, neurocognitive disorder.

Functional outcome measures show faster recovery with ‘partial’ versus total knee arthroplasty

For selected patients with knee osteoarthritis, unicompartmental (or “partial”) knee arthroplasty (UKA) shortens the recovery time for two key measures of physical function, as compared with total knee arthroplasty (TKA), reports a randomized trial in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

University Hospitals Performs First Arthroscopic Surgeries in Ohio using New ArthroFree® Wireless Camera System

University Hospitals (UH) today announced the completion of the first arthroscopic surgeries in Ohio, and amongst the first ever, using the new ArthroFree® Wireless Camera System. ArthroFree is the first wireless surgical camera system to receive market clearance from the U.S. Food and Drug Administration for use in broad endoscopic applications including arthroscopy.

UCSF Researchers Uncover New Pathway for Molecular Cancer Drug Therapies

In a study published December 8, 2022 in Science, UCSF researchers Kevin Lou, an MD-PhD student, Luke Gilbert, PhD, and Kevan Shokat, PhD, reveal the discovery of a cellular uptake pathway important for larger molecules. These large and complex molecules bind in unconventional ways to their targets, are efficiently taken up by target cells, and can be harnessed to create new drugs for the treatment of cancer and other diseases.

Research to Prevent Blindness Marks $400 Million in Funding to Advance Eye Disease Research

Research to Prevent Blindness announces a new round of awardees who are generating critical knowledge around a host of sight-threatening conditions. With this latest round of funding, RPB has provided more than $400 million in research funding.

Cheerful Chatbots Don’t Necessarily Improve Customer Service

Humans displaying positive emotions in customer service interactions have long been known to improve customer experience, but researchers at the Georgia Institute of Technology’s Scheller College of Business wanted to see if this also applied to AI. They conducted experimental studies to determine if positive emotional displays improved customer service and found that emotive AI is only appreciated if the customer expects it, and it may not be the best avenue for companies to invest in.

Sotorasib shows clinically meaningful activity in KRAS G12C-mutated advanced pancreatic cancer

In the Phase I/II CodeBreaK 100 trial, the KRAS G12C inhibitor sotorasib achieved meaningful anticancer activity with an acceptable safety profile in heavily pretreated patients with KRAS G12C-mutated metastatic pancreatic cancer, according to researchers at The University of Texas MD Anderson Cancer Center.

Building Bridges and Ladders in Astrophysics: Theory and Experiment Inform the Equation of State

Researchers are combining experimental, theoretical, and observational data on neutron stars to constrain the equation of state (EOS) and to glean the composition of their interiors. Different techniques probe the EOS at different densities, thereby creating a “density ladder” that aims to connect the various rungs. The findings indicate a possible phase transition in the interior of neutron stars.

At the Edge of Graphene-Based Electronics

Researchers at the Georgia Institute of Technology have developed a new graphene-based nanoelectronics platform that could be the key to finding a successor to silicon. The team may have also discovered a new quasiparticle. Their discovery could lead to manufacturing smaller, faster, more efficient, and more sustainable computer chips, and has potential implications for quantum and high-performance computing.

Stem Cell Transplants May Delay Disability Longer than Some MS Medications

In people with active secondary progressive multiple sclerosis (MS), hematopoietic stem cell transplants may delay disability longer than some other MS medications, according to a study published in the December 21, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study involved autologous hematopoietic stem cell transplants, which use healthy blood stem cells from a person’s own body to replace diseased cells.