Cleveland Clinic Study Adds to Increasing Evidence that Sugar Substitute Erythritol Raises Cardiovascular Risk

New Cleveland Clinic research shows that consuming foods with erythritol, a popular artificial sweetener, increases risk of cardiovascular events such as heart attack and stroke. The findings, from a new intervention study in healthy volunteers, show erythritol made platelets (a type of blood cell) more active, which can raise the risk of blood clots.

Texas Tech Health El Paso Associate Professor Receives Prestigious NIH Grant to Investigate Cause of Diabetic Pain

Researchers at Texas Tech Health El Paso and the University of Texas at Dallas will look at the origin of this neuropathic pain on a microscopic level in hope of finding ways to treat it without opioids. The groundbreaking research is funded by a $3.1 million, five-year R01 grant from the National Institutes of Health (NIH). Texas Tech Health El Paso is receiving $1.05 million of the grant.

Uncontrolled Hypertension: The Old ‘Silent Killer’ is Alive and Well

High blood pressure affects about 45% of U.S. adults. In the 1970s, only about 50% of patients were aware of their hypertension. Today, 54% are aware of their high blood pressure, 40% are actively treated and 21% are actively controlled. As such, researchers alert health care providers that the old “silent killer” is alive and well.

Low food security linked to metabolic syndrome in reproductive-aged Latinx females

Not having reliable access to food has a significant relationship with metabolic syndrome, a condition that increases risk for diseases such as diabetes and heart disease, in Latinx females of reproductive age, according to a study presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.

Metabolic Syndrome during Pregnancy Leads to Abnormal Development of Fat Tissue in Mouse Offspring

Article title: Accelerated developmental adipogenesis programs adipose tissue dysfunction and cardiometabolic risk in offspring born to dams with metabolic dysfunction Authors: Anna Mikolajczak, Nada A. Sallam, Radha D. Singh, Taylor B. Scheidl, Emma J. Walsh, Sebastian Larion, Carol Huang, Jennifer…

Exercise Reduces Medication for Metabolic Syndrome Management

Chances are that as we age, we will need to correct our blood pressure, blood sugar or blood fat with the help of medication. Thanks to such medication, an individual’s health span is extended by reducing cardiovascular and metabolic diseases…

Metabolic Syndrome Linked to Increased Risk of Second Stroke, Death

People with larger waistlines, high blood pressure and other risk factors that make up metabolic syndrome may be at higher risk for having a second stroke and even dying than people who do not have metabolic syndrome, according to a meta-analysis published in the July 28, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Exercise during Pregnancy Protects Kids’ Future Health from Parents’ Obesity

New research in mice suggests that exercising during pregnancy may help prevent children—especially boys—from developing health problems related to their parents’ obesity. The study is published ahead of print in the Journal of Applied Physiology. It was chosen as an APSselect article for February.

Multiomics, Gentational Cd Exposure, Estrogen Receptor Transactivation, and More Featured in December 2020 Toxicological Sciences

The December 2020 issue of the Society of Toxicology’s official journal, Toxicological Sciences, delivers cutting-edge toxicological research in endocrine toxicology, environmental toxicology, organ-specific toxicology, and more.

Ultraprocessed Food: Addictive, Toxic, and Ready for Regulation

Abstract Past public health crises (e.g., tobacco, alcohol, opioids, cholera, human immunodeficiency virus (HIV), lead, pollution, venereal disease, even coronavirus (COVID-19) have been met with interventions targeted both at the individual and all of society. While the healthcare community is…

Maternal Obesity May Cause Impaired Fetal Muscle Development and Metabolic Disorder

Article title: An obesogenic maternal environment impairs mouse growth patterns, satellite cell activation and markers of post-natal myogenesis Authors: Jasmine Mikovic, Camille R. Brightwell, Angus Lindsay, Yuan Wen, Greg Kowalski, Aaron P. Russell, Christopher S. Fry,  Séverine Lamon From the authors:…

Inflammatory Protein Found to Protect against Metabolic, Gut Changes in Mice

Article title: Lipocalin 2 deficiency-induced gut microbiota dysbiosis evokes metabolic syndrome in aged mice Authors: Vishal Singh, Sarah Galla, Rachel M. Golonka, Andrew D. Patterson, Benoit Chassaing, Bina Joe, Matam Vijay-Kumar From the authors: “Overall, the current study demonstrates that…

Research News Tip Sheet: Story Ideas From Johns Hopkins

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday, throughout the duration of the outbreak.

Coconut oil reduces features of metabolic syndrome in obese females, animal study finds

Obese females that ate a small amount of coconut oil daily, even as part of a high-fat diet, had decreased features of metabolic syndrome, a cluster of risk factors that raise the chances of developing diabetes, heart disease and stroke, an animal study finds. The study results were accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society.

Researchers Challenge New Guidelines on Aspirin in Primary Prevention

New guidelines recommend aspirin use in primary prevention for people ages 40 to 70 years old who are at higher risk of a first cardiovascular event, but not for those over 70. Yet, people over 70 are at higher risks of cardiovascular events than those under 70. As a result, health care providers are understandably confused about whether or not to prescribe aspirin for primary prevention of heart attacks or strokes, and if so, to whom.

Short-term Probiotics Regimen May Help Treat Gout, Kidney Disease

New research suggests that an individualized probiotic therapy regimen may improve symptoms of gout, gout-related kidney disease and other signs of metabolic syndrome. The study will be presented today at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.

High-fructose + high-fat diet damages mitochondria in the liver increasing risk of fatty-liver disease and metabolic syndrome

BOSTON – (October 1, 2019) – Researchers at Joslin Diabetes Center have found that high levels of fructose in the diet inhibit the liver’s ability to properly metabolize fat. This effect is specific to fructose. Indeed, equally high levels of glucose in the diet actually improve the fat-burning function of the liver. This explains why high dietary fructose has more negative health impacts than glucose does, even though they have the same caloric content.