Today, the Food and Drug Administration (FDA) announced the approval of mavacamten, a new drug shown to provide relief to obstructive hypertrophic cardiomyopathy patients experiencing shortness of breath.
Tag: Heart Failure
Could exercise counteract cardiotoxic chemotherapy for women with breast cancer
When you’re a breast cancer survivor, the last thing you need is another health scare. So, it’s concerning to know that up to 48 per cent of breast cancer patients will go on to fight heart disease as a direct result of chemotherapy.
Cardiologists, Cardiothoracic Surgeons Available for Expert Commentary Ahead of Upcoming Conferences
Cardiologists and cardiothoracic surgeons from the Smidt Heart Institute at Cedars-Sinai are available to discuss the latest advances in research, clinical care, transcatheter procedures and cardiothoracic surgery throughout the International Society for Heart and Lung Transplantation (ISHLT) Scientific Sessions 2022 and Heart Rhythm 2022.
Smidt Heart Institute: Annual Report Highlights
The 2022 Annual Report from the Smidt Heart Institute at Cedars-Sinai is available now, detailing the latest research and medical achievements by the expert team ranked No. 1 for cardiology and cardiac surgery in California by U.S. News & World Report.
Penn State College of Medicine receives $3 million for artificial heart research
Development of an implantable artificial heart that operates wirelessly and reliably for 10 years is the goal of an ongoing Penn State College of Medicine project.
Investigational Drug for Heart Failure has Little Impact on Exercise Tolerance
Heart failure patients taking the investigational drug omecamtiv mecarbil, which has been previously shown to improve long-term outcomes, see little impact on their ability to exercise compared to a placebo, according to a study supported by the Duke Clinical Research Institute.
Aspirin is linked with increased risk of heart failure
Aspirin use is associated with a 26% raised risk of heart failure in people with at least one predisposing factor for the condition.
Popular heart failure drug no better than older drug in sickest patients
A new study led by researchers at Washington University School of Medicine in St. Louis suggests that a widely used heart failure drug named sacubitril/valsartan is no better than valsartan alone in patients with severe heart failure. The study also provides evidence that the treatment with valsartan may be slightly safer for patients with advanced heart failure.
New cause of inherited heart condition discovered
A UCL-led research team has identified a new gene as a cause of hypertrophic cardiomyopathy, an inherited heart condition affecting one in 500 people.
Study links free radicals to heart damage caused by cancer
A new study in animal models shows that a cancer tumor alone can lead to cardiac damage, and suggests the culprits are free radicals interacting with cells in the heart. Adding antioxidants to food consumed by fruit flies with tumors reversed the damage to their hearts.
Mount Sinai Cardiologist Leads Effort to Outline Guidance for Management of Heart Failure Patients During COVID-19 Pandemic
New scientific statement aims to establish more streamlined care to improve outcomes in this high-risk group
Drinking sufficient water could prevent heart failure
Staying well hydrated throughout life could reduce the risk of developing heart failure, according to research presented at ESC Congress 2021.
Mount Sinai Heart Earns Two Prestigious Recognitions for Heart Failure and Catherization Lab
Awards highlight highest level of quality of care
Heart Cell Protein Could Lead to New Treatments for Heart Failure and Recovery
A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, according to an international study led by University of Utah Health scientists. T The finding suggests that drugs and other therapeutic treatments targeting this protein could eventually help alleviate heart failure.
Heart Failure Diagnoses May Be Missed in a Primary Care Setting for Women, Black Adults
Many heart failure diagnoses may be missed in a primary care setting.
Atlantic Health System and NYU Langone Health Announce Partnership on Organ Transplantation
Two of the leading names in health care in the tri-state region, New Jersey–based Atlantic Health System and New York–based NYU Langone Health, are teaming up to give patients greater access to heart and liver transplants and the coordinated, high-quality care needed to stay healthy. The clinical affiliation will partner NYU Langone’s nationally recognized transplant program with the nationally ranked Atlantic Health System Heart Care program located at Morristown Medical Center’s Gagnon Cardiovascular Institute (Morristown, NJ) and the ground-breaking liver services at Overlook Medical Center (Summit, NJ).
UH First in Northeast Ohio to Treat Patient with Heart Failure Using Cardiac Contractility Modulation
A University Hospitals (UH) patient is the first in Northeast Ohio to undergo a new, innovative procedure called CCM® therapy.
Cardiologists at Henry Ford Are First in U.S. to Implant New Device to Treat Heart Failure, Improve Kidney Function
Cardiologists at Henry Ford Hospital are first in the U.S. and second in the world to implant a circulatory support device that is being investigated in a clinical trial for patients hospitalized with acute decompensated heart failure (ADHF) and worsening kidney function, a condition known as cardiorenal syndrome.
Fat Around the Heart Linked to Increased Risk of Heart Failure
EMBARGOED UNTIL MAY 24 2:00PM EST (New York, NY – May 24, 2021) – Having excess pericardial fat—fat around the heart—increases the risk of developing heart failure, especially in women, according to new Mount Sinai research. Women with high amounts…
Novel Rehab Program Improves Outcome for Older Heart-failure Patients, Study Finds
Heart failure (HF) – when the heart can’t pump enough blood and oxygen through the body – affects approximately 6.2 million adults in the United States and is the primary cause of hospitalization in the elderly. Unfortunately, older adults with heart failure often have poor outcomes resulting in reduced quality of life, high mortality and frequent rehospitalizations.
Study Links Delirium to Hospitalized Older Adults with Acute Heart Failure Mortality
A possible link between delirium and mortality in hospitalized older adults with acute heart failure exacerbation has been found by researchers at The University of Texas Health Science Center at Houston (UTHealth).
Study Estimates Two-Thirds of COVID-19 Hospitalizations Due to Four Conditions
A new study estimates 64% of adult COVID-19 hospitalizations in the U.S. may have been prevented if there were less obesity, hypertension, diabetes, and heart failure. The model suggests notable differences by age and race/ethnicity in COVID-19 hospitalizations related to these conditions.
A New Beat Offers Free Online Seminar Examining Disparities in Cardiovascular Care During Heart Month
The Association of Black Cardiologists, Inc. (ABC) and the Cardiovascular Research Foundation (CRF) is offering a complimentary online seminar, “Tackling Disparities in CV Care: A Closer Look at Hypertension and Heart Failure” on Friday February 26, 2021. The program is part of a joint initiative called A New Beat which advocates for women and minorities rising as leaders in cardiology. It aims to foster careers of female and minority cardiologists, who can be poised to improve access to quality care for underserved populations.
Hershey Medical Center second in the nation to implant next generation heart device
Penn State Health Milton S. Hershey Medical Center became the second hospital in the nation to implant a newly-designed mechanical pump in a patient with severe heart failure.
Hypertensive Disorders of Pregnancy Associated with Risks of Structural Heart Changes a Decade After Delivery
The changes, which mainly affect the left ventricle of the heart, may predispose some women to ischemic heart disease and heart failure later in life.
UHN launches study to explore how Apple Watch can help with early identification of worsening heart failure
Dr. Heather Ross launches a clinical study, with Apple to test if remote monitoring with Apple Watch can help with early identification of worsening heart failure. Data collected using an Apple Watch will be compared to data routinely collected from rigorous physical tests patients normally undergo.
Move quickly to relax
A team of Wayne State University School of Medicine researchers led by Charles Chung, Ph.D., assistant professor of physiology, recently received a $1,894,271 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to address the critical need for new drug targets and diagnostic indexes for diastolic dysfunction using novel biomechanical tests that ultimately can be translated into clinical practice.
Uncovering a Link Between Inflammation and Heart Disease
In a new study in Circulation, researchers from Tufts University School of Medicine in collaboration with investigators at Vanderbilt University and Tufts Medical Center reveal a mechanism that is activating T cells, a type of immune cell, and causing inflammation in the heart.
Scientists ID Localized P2X7 Receptor as a Key to a Healthy Heart
Research in mice has found the P2X7 receptor (P2X7R) to be a key regulator of mitochondrial energy metabolism that enhances physical fitness. P2X7R is a channel that becomes activated in response to ATP, the organic compound that gives the body…
Enhanced Oral Uptake of Exosomes Opens Cell Therapy Alternative
Cell-derived exosomes are effective in treating disease when mixed with the dominant protein in breast milk and given orally, a new Smidt Heart Institute study of laboratory mice shows. The findings, published in the peer-reviewed Journal of Extracellular Vesicles, could help develop new oral medications for treating patients with muscular dystrophy and heart failure.
Common drug may protect hearts from damage caused by breast cancer chemotherapy
New research from UHN’s Peter Munk Cardiac Centre (PMCC) shows statins, commonly prescribed to lower cholesterol and reduce the risk of heart disease and stroke, may also protect the heart from damaging side-effects of early breast cancer treatment.
Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
Research News Tip Sheet: Story Ideas From Johns Hopkins Medicine
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
Does the New Heart Transplant Allocation Policy Encourage Gaming by Providers?
A new national policy was created to make determining who receives a heart transplant more fair. But new data shows it changed some practice patterns, too.
Diabetes Drug Can Treat and Reverse Heart Failure and Reduce Hospitalizations
Mount Sinai clinical trial results could help lead to FDA approval
Heart Failure Patients With COVID-19 Nearly Twice as Likely to Die and at Triple the Risk of Intubation Compared to Those Without Pre-Existing Heart Condition
Results may lead to closer monitoring of heart failure patients in hospital and at home
Ultrasounds Show Impact of COVID-19 on the Heart
International study may guide therapeutic strategies in patients with and without underlying heart conditions
High Fat or ‘Ketogenic’ Diets Could Prevent, Reverse Heart Failure
Research from Saint Louis University finds that high fat or “ketogenic” diets could completely prevent, or even reverse heart failure caused by a metabolic process.
Emerging Treatment Helps Reverse Heart Failure in Some Patients
In a new multicenter study, researchers led by University of Utah Health physicians report that an emerging heart failure treatment could potentially reverse structural damage to the heart, allowing it to heal itself over time. Overall, 19 (40%) patients who were treated with a combination of LVAD support with heart failure medications had sufficient improvement that the LVAD could be removed.
Does the New Heart Transplant Allocation Policy Encourage Gaming by Providers?
A new national policy was created to make determining who receives a heart transplant more fair. But new data shows it changed some practice patterns, too.
What Fuels the Beating Heart? Study Reveals Nutrients Used by Normal and Failing Hearts
A team led by Penn scientists produced a detailed picture of fuel and nutrient use by the human heart. The study was the first of its kind, involving the simultaneous sampling of blood from different parts of the circulatory system in dozens of human participants, in order to record the levels of related molecules going into and coming out of the beating heart.
Penn Researchers Receive Grant to Use AI to Improve Heart Transplant Outcomes
Researchers in the Perelman School of Medicine at the University of Pennsylvania were awarded a $3.2 million grant from the NIH to enhance research for improving heart transplant outcomes for patients. The four-year grant will fund a project exploring the use of AI-driven analysis to determine the likelihood of cardiac patients accepting or rejecting a new heart.
Exosome treatment improves recovery from heart attacks in a preclinical study
Research in pigs shows that using the exosomes naturally produced from a mix of heart muscle, endothelial and smooth muscle cells — all derived from human induced pluripotent stem cells — yields regenerative benefits equivalent to the injected human induced pluripotent stem cell-cardiac cells.
UHN features Apple Watch in a new study to advance remote management of heart failure
The Ted Rogers Centre for Heart Research, at the Peter Munk Cardiac Centre (University Health Network) are collaborating with Apple, Inc., to give heart failure patients even more control over their health, and usher in a new era of remote monitoring possibilities.
Mount Sinai Health System Hospitals Receive Top Quality Achievement Awards for Stroke and Cardiac Care
Mount Sinai Health System Hospitals Receive Top Quality Achievement Awards for Stroke and Cardiac Care
Study Shows Socioeconomic Status Linked to Heart Failure Mortality in United States
A variety of treatments exist to address heart disease, yet it continues to carry a poor prognosis. A new study from University Hospitals showed that a person’s address can help predict their chance of mortality from heart disease.
Gender Parity in Heart Failure Research: More Female Authors Could Mean More Female Participants
Representation of women leading heart failure research remains limited, according to new research led by Penn Medicine. The authors say the findings point to a need to support great gender diversity among researchers to drive diversity among clinical trial participants and even improve patient outcomes.
UNC Researchers Find Increase in Comorbidities among Hospitalized Patients with Heart Failure
A study recently published in the journal Circulation looks at temporal trends in the burden of comorbidities and associated risk of mortality among patients with heart failure (HF) with preserved ejection fraction (HFpEF), in which the left ventricle of the heart is not able to relax enough to fill properly with blood, and HF with reduced ejection fraction (HFrEF), in which the left ventricle is not able contract enough to pump out as much blood.
Pinney named co-director of UChicago Medicine Heart & Vascular Center
Cardiologist and heart failure expert Sean Pinney, MD, has been named co-director of the Heart & Vascular Center and director of the Advanced Heart Failure, Transplant and Mechanical Circulatory Support Program at the University of Chicago Medicine.
ChAT Neuron Activation in Rat Heart Reduces Heart Failure-induced Dysfunction, Death
Article title: Chemogenetic activation of intracardiac cholinergic neurons improves cardiac function in pressure overload-induced heart failure Authors: Jhansi Dyavanapalli, Aloysius James Hora, Joan B. Escobar, John Schloen, Mary Kate Dwyer, Jeannette Rodriguez, Christopher F. Spurney, Matthew W. Kay From the authors: “The…