English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduM1 macrophages “commit” to a glycolytic state when endogenous nitric oxide (NO) reprograms mitochondrial metabolism by limiting aconitase (Aco)-2 and pyruvate dehydrogenase (PDH). Here we provide evidence that NO directly targets the PDH complex using lipoate to generate nitroxyl (HNO).…
Tag: mitochondrial metabolism
Removal of AKAP11 Protein by Autophagy as a Key to Fuel Mitochondrial Metabolism and Tumor Cell Growth Through Activating Protein Kinase A (PKA)
MEDIA ADVISORY FOR IMMEDIATE RELEASE: Proceedings of the National Academy of Sciences of the United States (PNAS) Published Online on March 30, 2021 Mount Sinai Researchers Find “Removal of AKAP11 protein by autophagy as a key to fuel mitochondrial metabolism and…
Scientists ID Localized P2X7 Receptor as a Key to a Healthy Heart
Research in mice has found the P2X7 receptor (P2X7R) to be a key regulator of mitochondrial energy metabolism that enhances physical fitness. P2X7R is a channel that becomes activated in response to ATP, the organic compound that gives the body…