mRNA Vaccines Slash Risk of COVID-19 Infection by 91 Percent in Fully Vaccinated People

People who receive mRNA COVID-19 vaccines are up to 91 percent less likely to develop the disease than those who are unvaccinated, according to a new nationwide study of eight sites, including Salt Lake City. For those few vaccinated people who do still get an infection, or “breakthrough” cases, the study suggests that vaccines reduce the severity of COVID-19 symptoms and shorten its duration.

Partners in Crime: Genetic Collaborator May Influence Severity of the Rare Disease, NGLY1

In 2012, four-year-old Bertrand Might became the first-ever patient diagnosed with a rare genetic disorder called N-glycanase (NGLY1) deficiency. Since then, more than 60 additional patients have been found. University of Utah Health geneticist Clement Chow is investigating the disease, which affects every system of the body.

Informatics Approach Helps Reveal Risk Factors for Pressure Injuries

Researchers used informatics to examine 5,000+ patient records and five years of data related to nursing skin assessments and hospital-acquired pressure injuries. The results underscore the importance of treating and monitoring irritated skin early and eliminating the cause as an important step to prevent pressure injuries.

Emerging Treatment Helps Reverse Heart Failure in Some Patients

In a new multicenter study, researchers led by University of Utah Health physicians report that an emerging heart failure treatment could potentially reverse structural damage to the heart, allowing it to heal itself over time. Overall, 19 (40%) patients who were treated with a combination of LVAD support with heart failure medications had sufficient improvement that the LVAD could be removed.

Follow-Up Appointments for Children Hospitalized for Bronchiolitis May Not Be Needed; New Study Findings Could Guide Treatment During COVID Pandemic

A new study at Intermountain Primary Children’s Hospital in Salt Lake City has found that follow-up appointments for hospitalized children treated for childhood bronchitis are often not necessary, and that switching from mandatory to “as-needed” follow-up care can save families from unnecessary medical care and expense – and may help guide treatment during the COVID-19 pandemic.

Two Major COVID-19 Clinical Trials Launched to Determine Effectiveness and Safety of Drugs in Treating Coronavirus

Researchers from Intermountain Healthcare and University of Utah Health in Salt Lake City have launched two vital clinical trials to test the effectiveness and safety of two drugs – hydroxychloroquine (HCQ) and azithromycin – to treat patients with COVID-19.

No Benefit Found in Using Broad-spectrum Antibiotics as Initial Pneumonia Treatment

Doctors who use drugs that target antibiotic-resistant bacteria as a first-line defense against pneumonia should probably reconsider this approach, according to a new study of more than 88,000 veterans hospitalized with the disease. The study found that pneumonia patients given these medications in the first few days after hospitalization fared no better than those receiving standard medical care for the condition.