Novel antiviral strategy for treatment of COVID-19

A research team led by Professor Hongzhe SUN, Norman & Cecilia Yip Professor in Bioinorganic Chemistry, Department of Chemistry, Faculty of Science, and Professor Kwok Yung YUEN, Henry Fok Professor in Infectious Diseases, Department of Microbiology, Li Ka Shing Faculty of Medicine of the University of Hong Kong (HKU), has discovered a novel antiviral strategy for treatment of COVID-19.

Review of proposed FDA regulation reveals the extent of financial ties to industry

The findings come from a cross-sectional study, published in BMJ Open, of the comments submitted to the US Food and Drug Administration (FDA) ‘Proposed Regulatory Framework for Modifications to Artificial Intelligence/Machine Learning (AI/ML)-Based Software as a Medical Device (SaMD)–Discussion Paper and Request for Feedback’.

Fuels, not fire weather, control carbon emissions in boreal forest, new study finds

Northern Arizona University researcher Xanthe Walker is the lead author on research published this week that found that the amount of carbon stored in soils was the biggest predictor of how much carbon would combust and that soil moisture also was significant in predicting carbon release.

Healthy skepticism: People may be wary of health articles on crowdsourced sites

People may be skeptical about medical and health articles they encounter on crowdsourced websites, such as Wikipedia and Wikihealth, according to researchers. While that may be good news for health officials who are worried that these sites allow non-experts to easily add and edit health information, the researchers added that having medical professionals curate content on those sites may not reduce the skepticism.

Ultrasound Technique Offers More Precise, Quantified Assessments of Lung Health

Researchers have developed a technique that uses ultrasound to provide non-invasive assessments of pulmonary fibrosis and pulmonary edema. The technique has been shown to both quantify lung scarring and detect lung fluid in rats. A study on pulmonary edema in humans is under way.

UT Southwestern Leads National Efforts Around Childhood Blood Disorders

DALLAS – Oct.15, 2020 – When a child has a rare blood disorder, clinicians can struggle to find the best diagnostic and treatment methods. New research led by UT Southwestern shows the effectiveness of a treatment for aplastic anemia and reveals the range of diagnosis and treatment options used by hospitals around the country for a related disease – myelodysplastic syndrome (MDS).

Huge Study Links Risky Drinking with Low Social Support and Area of Residence

People who report having low social support are substantially more likely to experience heavy drinking and binge drinking than those who feel more supported, a large European study suggests. The researchers also found strong evidence that risky drinking is associated with areas of residence. Although alcohol use is known to be linked to social, economic, and demographic factors, the research is incomplete; it is not clear to what extent some of these factors, especially environmental conditions, predict dangerous drinking. Investigators in Spain designed a study that was unusual in exploring both heavy drinking and binge drinking and both individual and contextual (environmental) factors. The study, in Alcoholism: Clinical & Experimental Research, confirmed individual risk factors and highlighted certain environmental conditions that may help target interventions for those at risk.

The rise of ‘Zoom Towns’ in the rural west

COVID-19 has expedited a trend of migration into western gateway communities—remote workers are fleeing cities to ride out the pandemic. A new study using data from 2018 found that growing populations caused urgent planning pressures, and officials felt unprepared to respond to and prepare for problems associated with rapid growth.

IU Kelley School of Business research finds that blue-light glasses improve sleep and workday productivity.

During the pandemic, the amount of screen time for many people working and learning from home as well as binge-watching TV has sharply increased. New research finds that wearing blue-light glasses just before sleeping can lead to a better night’s sleep and contribute to a better day’s work to follow.

Meta-Analysis of Bivalirudin vs. Heparin in Patients with MI Examines Mortality and Bleeding Rates

An individual patient data pooled analysis comparing the use of bivalirudin versus heparin in heart attack patients undergoing percutaneous coronary intervention (PCI) found that bivalirudin use was associated with similar overall rates of 30-day mortality across all heart attack patients, but lower rates of serious bleeding events. Moreover, mortality was reduced in patients with ST-segment elevation myocardial infarction (STEMI) who were treated with a post-PCI bivalirudin infusion.

Combined FFR and OCT Imaging Can Improve Accuracy of High-Risk Lesion Identification in Patients with Diabetes

Data from COMBINE (OCT-FFR) found that the use of FFR combined with OCT imaging can help improve the accuracy of high-risk lesion identification in patients with diabetes. Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world’s premier educational meeting specializing in interventional cardiovascular medicine.

Pilot Randomized Trial Demonstrates that PCI of Non-Flow-Limiting Vulnerable Plaques May be Safe with Favorable Long-Term Clinical Outcomes

New data from PROSPECT ABSORB, a pilot randomized trial of percutaneous coronary intervention (PCI) of non-flow-limiting vulnerable plaques in native coronary arteries, found that PCI was safe, substantially enlarged follow-up lumen areas, and was associated with favorable long-term clinical outcomes.

NIRS-IVUS Imaging Can Help Identify High-Risk Plaques That Can Lead to Adverse Outcomes

ew data from the PROSPECT II study shows that NIRS-IVUS intracoronary imaging can help identify angiographically non-obstructive lesions with high-risk characteristics for future adverse cardiac outcomes. Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world’s premier educational meeting specializing in interventional cardiovascular medicine.

Berkeley Lab Scientists Contribute to New Exploration of Higgs Boson Interactions

A new analysis, featuring important contributions by Berkeley Lab scientists, strongly supports the hypothesis that the Higgs boson interacts with muons, which are heavier siblings of electrons and the lightest particles yet to reveal evidence for these interactions.

Pandemic lockdowns caused steep and lasting carbon dioxide decline

An international team of climate experts, including Earth system scientists at the University of California, Irvine, today released an assessment of carbon dioxide emissions by industry, transportation and other sectors from January through June, showing that this year’s pandemic lockdowns resulted in a 9 percent decline from 2019 levels.

Concerns about violence increase in California amid COVID-19 pandemic

A new study by the UC Davis Violence Prevention Program looked at the intersection of the coronavirus pandemic and violence-related harms in California. It found that COVID-19 pandemic was linked to an estimated 110,000 firearm purchases in California and increases in individuals’ worries about violence.

Protein that Keeps Immune System from Freaking Out Could Form Basis for New Therapeutics

Treatment with a peptide that mimics the naturally occurring protein GIV prevents immune overreaction and supports a mechanism critical for survival in mouse models of sepsis and colitis, according to a UC San Diego study.

‘Honey bee, it’s me’

For a honey bee, few things are more important than recognizing your nestmates. Being able to tell a nestmate from an invader could mean the difference between a honey-stocked hive and a long, lean winter. New research from Washington University in St. Louis shows that honey bees rely on chemical cues related to their shared gut microbial communities, instead of genetic relatedness, to identify members of their colony.

COVID-19 rapid test has successful lab results, research moves to next stages

Rapid detection of the SARS-CoV-2 virus, in about 30 seconds following the test, has had successful preliminary results in Mano Misra’s lab at the University of Nevada, Reno.

Aerosols vs droplets

Winter is on its way. And in this year of coronavirus, with it comes the potential for a second wave of COVID-19. Add in flu season and our tendency to head inside and close our windows to the cold, wet weather, and it appears the next several months are going to present us with new health challenges.

Researchers Use Lab-grown Tissue Grafts for Personalized Joint Replacement

A multidisciplinary team from Columbia Engineering, Columbia’s College of Dental Medicine and Department of Medicine, Louisiana State University, LaCell LLC, and Obatala Sciences has now bioengineered living cartilage-bone temporomandibular joint grafts, precisely matched to the recipient, both biologically and anatomically. Their new study, published today in Science Translational Medicine, builds upon a long series of their previous work on bioengineering functional cartilage and bone for regenerative medicine and tissue models of disease.