Study Shows Profound Benefit with Targeted Therapy for Patients with Early Stage NSCLC

According to findings led by researchers at Yale Cancer Center, treatment with the targeted therapy osimertinib following surgery significantly improves disease-free survival (DFS) in patients with early-stage, non-small cell lung cancer (NSCLC) with EGFR gene mutations.

Developing Culturally Responsive Strategies to Help African American Women Overcome Barriers to Good Heart Health

Research has shown African American women have disproportionately higher rates of cardiovascular disease risk factors compared to their white counterparts. UK College of Health Sciences assistant professor Brandi White has been working with African American women living in public housing on Lexington’s East End to develop culturally responsive strategies to overcome social and economic barriers to a heart-healthy lifestyle and reduce their cardiovascular disease risk.

Bone Researcher Provides Expert Commentary in Publication’s Controversial Reversal of Long-Held Theory

The latest issue of PLOS Genetics includes two publications that challenge the basic assumptions behind 24 years of bone and metabolism research, and given the magnitude of the potential paradigm shift, the editors turned to Stavros C. Manolagas, M.D., Ph.D., of the University of Arkansas for Medical Sciences (UAMS) to provide expert commentary and context.

As ORNL builds novel reactor, nuclear industry benefits from technology

Scientists at DOE’s Manufacturing Demonstration Facility at Oak Ridge National Laboratory working on the Transformational Challenge Reactor, a microreactor built using 3D printing, find their work may revolutionize manufacturing in the nuclear industry — and in other industries, too.

Patients still not telling MDs about use of natural health products

The research team conducted the patient survey between November 2018 and February 2019 at the Robert Schad Naturopathic Clinic in Toronto.
Based on 277 completed questionnaires, 99 per cent of the patients surveyed were using natural health products, and 46 per cent were using natural health products and prescription medications concurrently. Of those using natural health products, 42 per cent did not disclose use to their primary care physician.

Anesthesia Practices See Major Financial Hit as Physician Anesthesiologists Pivot During COVID-19 to Treat Patients in Critical Care and ICUs, ASA Survey Highlights

A recent survey of anesthesia administrators and executive members of the American Society of Anesthesiologists (ASA) finds a majority of physician anesthesiologists pivoted from working in the operating room to treating COVID-19 patients in critical care units and ICUs, making the most of their expertise in intubation, ventilation strategies, and critical care medicine, which includes all aspects of resuscitation with multiorgan failure.

Study: Climate Scientists Create Model for Global Forest Growth Through 2060

In a new study, researchers at the University at Albany have turned to more than a century’s worth of data (from 1901 to 2012) in NOAA’s International Tree Ring Data Bank to both analyze historical tree growth at 3,579 forests around the world and create a model for future projections (from 2045 to 2060).

Plasma science report co-chaired by UAH astrophysicist urges better federal agency coordination

Federal agencies should better coordinate their activities in plasma science and engineering (PSE) and jointly support new funding opportunities that take advantage of PSE’s overlaps with different science disciplines, according to a decadal report by the National Academy of Sciences (NAS).

KIDNEY HEALTH INITIATIVE URGES THE ACCELERATION OF HOME THERAPY TECHNOLOGY IN RESPONSE TO CORONAVIRUS 2019 (COVID-19)

The COVID-19 pandemic highlights the vulnerability of people with kidney failure who rely on in-center hemodialysis. People with kidney failure are at high risk of severe COVID-19 complications and are exposed to infection due to a kidney replacement therapy process that requires traveling to a dialysis facility multiple times a week.

Thomas Jackiewicz Appointed President of University of Chicago Medical Center, COO of UChicago Medicine health system

Thomas E. Jackiewicz, a leader with extensive experience in top academic health systems and medical schools, has been appointed the new president of the University of Chicago Medical Center and chief operating officer of the UChicago Medicine health system, succeeding Sharon O’Keefe, who earlier announced her plans to retire in July 2020.

Autism severity can change substantially during early childhood

A UC Davis MIND Institute study found that around 30% of young children with autism have less severe autism symptoms at age 6 than they did at age 3, with some losing their autism diagnoses entirely. It also found that girls tend to show greater reduction and less rise in their autism symptom severity than boys with autism. Children with higher IQs were more likely to show a reduction in their symptoms.

Study: Exposure to police violence may be more impactful for individuals who perceive police as a threat to their personal safety

New research from the Race and Opportunity Lab in the Brown School’s Center for Social Development at Washington University in St. Louis sheds light on youths’ reactions to social media videos showing violence in their communities. “Exposure to police violence may be more impactful for individuals who perceive police as a threat to their personal safety,” the lead author said.

UNH Researchers Find Wildfires Can Alter Arctic Watersheds for 50 Years

Climate change has contributed to the increase in the number of wildfires in the Arctic where it can dramatically shift stream chemistry and potentially harm both ecosystems and humans. Researchers at the University of New Hampshire have found that some aftereffects, like decreased carbon and increased nitrogen, can last up to five decades and could have major implications on vital waterways.

Researchers @UCSDMedSchool found that using electronic-based consent forms (eConsents) decreased error rates from 32% to 1%, helping to decrease delays to surgery.

In a recent study published in JAMA Surgery, researchers at University of California San Diego School of Medicine found that using electronic-based consent forms (eConsents) decreased the error rate from 32 percent to 1 percent. “You are not relying on…

MSK: Cancer Isn’t Sheltering in Place

As the height of the COVID-19 outbreak in New York City and the Tri-State area begins to subside, Memorial Sloan Kettering Cancer Center oncologists are urging patients to schedule cancer screenings and treatments now – as the long-term toll of missed diagnoses and delayed treatments could be devastating for patients and their loved ones across the region and the country.

TCT 2020 Is Now a Virtual Event: TCT Connect

The Cardiovascular Research Foundation (CRF) has announced that Transcatheter Cardiovascular Therapeutics (TCT) 2020 will now take place as a virtual event called TCT Connect. The event will take place online October 14-18, 2020 and feature live case-based transmissions from around the globe, late-breaking clinical trials and science, virtual training, and countless opportunities to learn and engage with the brightest minds in interventional cardiovascular medicine.

Study Shows Uptick in At-Home Pediatric Fractures During COVID-19 Pandemic

COVID-19 social distancing measures, including the closure of schools and parks and the indefinite cancellation of team sports, have led to a nearly 60% decrease overall in pediatric fractures but an increase in the proportion of fractures sustained at home, according to a new study by researchers at Children’s Hospital of Philadelphia (CHOP). The findings, published in the Journal of Pediatric Orthopaedics, suggest a need for increased awareness of at-home safety measures.

Material and genetic resemblance in the Bronze Age Southern Levant

Different “Canaanite” people from the Bronze Age Southern Levant not only culturally, but also genetically resemble each other more than other populations. A team around Ron Pinhasi from the Department of Evolutionary Anthropology found in a recent study that their DNA is a mixture of two populations: The Chalcolithic Zagros and Early Bronze Age Caucasus. The results have been published in “Cell”.

PCR and CRF Announce Partners in Learning Virtual Sessions

PCR and CRF are pleased to announce the creation of virtual Partners in Learning sessions that will be broadcast during the PCR e-Course (June 25-27, 2020) and CRF’s TVT Connect meeting (June 18-28, 2020). The sessions, which will cover coronary artery disease in TAVI patients and TAVI in low risk patients, are part of a collaborative educational series from the two groups.

Combination therapy well-tolerated and highly effective for patients with IDH1-mutated acute myeloid leukemia (AML)

A combination therapy of ivosenidib (IVO) plus venetoclax (VEN) with or without azacitidine (AZA) was found to be effective against a specific genetic subtype of acute myeloid leukemia (AML) in a Phase Ib/II trial led by researchers at The University of Texas MD Anderson Cancer Center. The results of this trial may support a novel course of action for patients with AML harboring an IDH1 mutation who have historically had few treatment options.

Novel targeted drug induced positive response for patients with von Hippel-Lindau disease–associated kidney cancer

In an international trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with MK-6482, the small molecule inhibitor of hypoxia-inducible factor (HIF)-2a was well tolerated and resulted in clinical responses for patients with von Hippel-Lindau disease (VHL)–associated renal cell carcinoma (RCC).

Laser, Biosciences Researchers Combine Efforts to Study Viruses in Droplets

Laser and biology experts at Berkeley Lab are working together to develop a platform and experiments to study the structure and components of viruses like the one causing COVID-19, and to learn how viruses interact with their surrounding environment. The experiments could provide new insight on how to reduce the infectiousness of viruses.

Alcohol Use in Early Adolescence may Alter Reward Motivation

The brain responds to rewarding stimuli by increasing the release of a neurotransmitter called dopamine. When we feel motivated, it is because our brain anticipates this dopamine reward.
The transition from early to mid-adolescence is associated with increased reward sensitivity and reward-seeking behavior, a consequence of normal brain development. This heightened sensitivity or prioritization of reward can be thought of as reflecting a greater motivation to obtain rewards. A new study, published in Alcoholism: Clinical and Experimental Research, has addressed whether drinking alcohol in early adolescence might impact the brain’s reward systems, by examining associations between alcohol initiation and subsequent changes in reward motivation while accounting for baseline scores. Differences between boys and girls were also evaluated.