English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduA pivotal study has shed light on the genetic factors that govern the ability of highbush blueberries to regenerate from shoots, a critical process for plant breeding and genetic engineering. By comparing the transcriptomes of two genotypes with contrasting regeneration rates, researchers identified key auxin-related genes and transcription factors crucial to this process.
Tag: Transcriptome
Soybean seed hardness demystified: key genes and networks uncovered
Soybean seed hardness, a key factor in consumer acceptance and vegetable soybean quality, has been elucidated through a comprehensive study. Researchers identified the genetic and molecular mechanisms influencing this trait, focusing on differential gene expression during seed development. The discovery of the GmSWEET2 gene as a significant regulator of hardness offers a pathway to enhance soybean texture, potentially revolutionizing the market with customized varieties to suit diverse consumer preferences.
Sequencing of the developing human brain uncovers hundreds of thousands of new gene transcripts
Using new sequencing technologies, UCLA and University of Pennsylvania researchers uncovered 214,516 unique isoforms in the developing neocortex — over 70% of which have not been previously studied.
Studying the Blood Transcriptome May Improve Understanding of Variability in Exercise Response
Article title: Novel whole blood transcriptome signatures of changes in maximal aerobic capacity in response to endurance exercise training in healthy women Authors: Thomas J. LaRocca, Meghan E. Smith, Kaitlin A. Freeberg, Daniel H. Craighead, Timothy Helmuth, Matthew M. Robinson,…
Mitochondrial Changes Linked to High Blood Pressure in Pregnancy
A new study provides evidence for the possibility that mitochondrial dysregulation could be a contributing factor in the development of hypertensive disorders of pregnancy. The study is published in Physiological Genomics. It was chosen as an APSselect article for July.
Breakthrough microscopy technique “supersizes” cells to reveal genetic activity
Breakthrough microscopy techniques are helping researchers visualize the ways our molecules interact with the human genome. Researchers at Yale School of Medicine used a series of expandable gels to pull apart a cell and expand it to 4000 times its…
A roadmap for gene regulation in plants
For the first time, researchers have developed a genome-scale way to map the regulatory role of transcription factors, proteins that play a key role in gene expression and determining a plant’s physiological traits. Their work reveals unprecedented insights into gene regulatory networks and identifies a new library of DNA parts that can be used to optimize plants for bioenergy and agriculture.
Vitamin A May Protect Heart from Some Effects of Obesity
Research in a mouse model of diet-induced obesity found greater disruption to genes involved in heart function when coupled with vitamin A deficiency. The study is published in the American Journal of Physiology-Heart and Circulatory Physiology. It was chosen as an APSselect article for January.
RNA Sequencing of Whole Blood in Female Triathletes Explores Effects of Endurance Exercise on Gene Expression
Article title: Whole blood transcriptome characterization of young female triathlon athletes following an endurance exercise: a pilot study Authors: Attila Bácsi, András Penyige, Gergely Becs, Szilvia Benkő, Elek Gergő Kovács, Csaba Jenei, István Pócsi, József Balla, László Csernoch, Ildikó Balatoni…
Study of Body Weight-associated Genes in Rats May Inform Regulation of Obesity in Humans
Article title: Transcriptome-wide analyses of adipose tissue in outbred rats reveal genetic regulatory mechanisms relevant for human obesity Authors: Wesley L. Crouse, Swapan K. Das, Thu Le, Gregory Keele, Katie Holl, Osborne Seshie, Ann L. Craddock, Neeraj K. Sharma, Mary…
New Approach Methodologies, Single Cell RNAseq, and More Featured in 2021 Toxicological Sciences
Toxicological Sciences delivers cutting-edge research in toxicology in the areas of clinical and translational toxicology, emerging technologies, and more in the August 2021 issue.
Spontaneous Mammary Neoplasia, Cannabidiol Exposure, Aryl Hydrocarbon Receptors, and More Featured in July 2021 Toxicological Sciences
Toxicological Sciences delivers the latest toxicology research in the July 2021 issue. The issue features investigations in delivers the latest toxicology research in areas such as exposure to delta-9-tetrahydrocannabinol and cannabidiol, effects of ENDS vapors on amino acid metabolism, and more.
Epitranscriptomics, Xenobiotic Nuclear Receptors, Arsenic Exposure, and More Featured in May 2021 Toxicological Sciences
Research on biomarkers, carcinogenesis, regulatory science, and more is available in the latest issue of Toxicological Sciences.
Xenobiotic Receptor Activation, CRISPR/Cas9, Magnetic Resonance-Guided Radiotherapy, and More Featured in May 2020 Toxicological Sciences
During these difficult times, the Society of Toxicology’s official journal, Toxicological Sciences, remains a source for leading research in toxicology, including in the areas of biomarkers, carcinogenesis, and organ-specific toxicology.