Hormone therapy could lower risk of immunotherapy-associated myocarditis in women

A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center and the University of California San Francisco (UCSF) has discovered the underlying cause of gender differences in immunotherapy-associated myocarditis after immune checkpoint inhibitor (ICI) treatment. Their findings point to possible treatment strategies for this side effect, which disproportionately affects female patients.

Many middle-aged adults wary of taking part in studies of dementia prevention drugs

Drug companies and university-based teams are working urgently to find and test new medications that could prevent or slow the decline of brain function in older adults. But a new study suggests they’ll need to work harder to find volunteers for their clinical trials.

Patient-specific cancer tumours replicated in 3D bioprinting advance

Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumours in 3D models. The University of Bristol-led advance, published in Biofabrication, would allow clinicians to treat the models, known as spheroids, with chemotherapy drugs and radiation to help them understand an individual patient’s resistance to therapies.

Inequality linked to differences in kids’ brain connections

Growing up in a socioeconomically disadvantaged household may have lasting effects on children’s brain development, a large new study suggests. Compared with children from more-advantaged homes and neighborhoods, children from families with fewer resources have different patterns of connections between their brain’s many regions and networks by the time they’re in upper grades of elementary school.
One socioeconomic factor stood out in the study as more important to brain development than others: the number of years of education a child’s parents have.

Infants less likely to contract COVID, develop severe symptoms than other household caregivers

In one of the first studies to explore how COVID-19 specifically affects older infants, researchers from the University of Washington and at institutions at four other locations in the Western and Southern U.S. found that the number of infected people in a household was the factor most closely linked with the infant’s likelihood of being infected.

Permanent daylight saving time would reduce deer-vehicle collisions, study shows

Adopting permanent DST in the United States would reduce deer-vehicle collisions and likely prevent an estimated 36,550 deer deaths, 33 human deaths, 2,054 human injuries and $1.19 billion in costs each year. Deer-vehicle collisions would decrease under permanent DST because skies would be brighter later in the evening

American College of Rheumatology Educating Dermatologists and Nephrologists on Lupus Clinical Trials Racial Disparities

The American College of Rheumatology (ACR) has released Continuing Medical Education (CME) for dermatologists and nephrologists to help them learn more about clinical trials for lupus patients in their treatment areas and the importance of getting more of African American/Black patients enrolled.

Sylvester’s Sexual Health After Cancer Program Expands to Meet Needs of Women with Cancer

Kristin E. Rojas, M.D., FACS, FACOG, assistant professor of surgical oncology in the DeWitt Daughtry Department of Surgery and Sylvester Comprehensive Cancer Center at the University Miami Miller School of Medicine, realized she had struck a chord with women being…

Biological Sex, Heart Disease Risk Factors Can Influence Relationship between Cardiorespiratory Fitness Level and Brain Blood Flow

Article title: Influence of sex and presence of cardiovascular risk factors on relations between cardiorespiratory fitness and cerebrovascular hemodynamics Authors: Wesley K. Lefferts, Cynthia M. Weiner, Sara E. Mascone, Jacqueline A. Augustine, Kevin S. Heffernan, Elizabeth C. Lefferts From the…

New Research on Neuronal Response to Calcium Imaging Aid Interpretation of Data without Electrophysiology Recordings

Article title: Simultaneous whole-cell patch-clamp and calcium imaging on myenteric neurons Authors: Zhiling Li, Werend Boesmans, Youcef Kazwiny, Marlene M. Hao, Pieter Vanden Berghe From the authors: “Our findings will help in the interpretation of calcium imaging data without the…

New Tool for Estimating People’s Total Exposure to Potentially Harmful Chemicals Is Developed

A novel metric that estimates our “burden,” or cumulative exposure, to a family of thousands of synthetic chemicals that we encounter in everyday life with potentially adverse health impacts, has been created by a team of researchers at Mount Sinai.