A new model for understanding which patients with sepsis, Covid-19 and influenza have immune dysfunction and are more likely to suffer poor outcomes has been developed by researchers at the Wellcome Sanger Institute, the University of Oxford, Queen Mary University, Imperial College and their collaborators.
Month: November 2022
Plant hormones to help prevent Striga invasion
As part of a multipronged approach to prevent infestations by the parasitic plant Striga hermonthica, researchers are unravelling the role of plant hormones, known as strigolactones (SLs).
Protected areas buffer climate change for biodiversity
Climate change is emerging as a top threat to biodiversity according to the latest Global Assessment Report on Biodiversity and Ecosystem Services.
Pediatric Multicenter Study Shows Targeted Therapy for High-Risk Hodgkin Lymphoma Reduces Relapse
A targeted therapy for children with high-risk Hodgkin lymphoma significantly reduced relapse rates, a large multicenter clinical trial conducted by the Children’s Oncology Group shows. The study results have been reported in the New England Journal of Medicine.
New large-scale virtual model of cortex highly successful in solving visual tasks
HBP researchers have trained a large-scale model of the primary visual cortex of the mouse to solve visual tasks in a highly robust way.
How Scientist Designed a System for Pose Determination of Spacecraft Using Time-of-Flight Sensors?
Spacecraft pose determination is aimed at acquiring the relative pose of the active spacecraft like nanosatellites to the target.
Chronic pain associated with poor health – and COVID-19 infection – decades later
Data on more than 12,000 Britons also shows links with subsequent poor mental health, worse sleep, joblessness.
Reduced nicotine cigarettes result in less smoking in anxious, depressed smokers
Lowering the amount of nicotine in cigarettes to non-addictive levels may reduce smoking without worsening mental health in smokers with mood or anxiety disorders, according to College of Medicine researchers.
Hormone therapy could lower risk of immunotherapy-associated myocarditis in women
A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center and the University of California San Francisco (UCSF) has discovered the underlying cause of gender differences in immunotherapy-associated myocarditis after immune checkpoint inhibitor (ICI) treatment. Their findings point to possible treatment strategies for this side effect, which disproportionately affects female patients.
A stone age child buried with bird feathers, plant fibres and fur
The exceptional excavation of a Stone Age burial site was carried out in Majoonsuo, situated in the municipality of Outokumpu in Eastern Finland.
Paxlovid and COVID Rebound – Ochsner Health Experts Available
When Paxlovid became available for wider use earlier this year, multiple reports of COVID rebound in patients who had taken the antiviral treatment soon followed, leading some doctors to reconsider prescribing it for lower-risk patients. However, a new study has…
COVID lockdown affected early childhood development – Expert Available
A study out of Ireland has finally shed light on a question that many parents and caregivers have shared since the start of the pandemic: how COVID lockdown could affect their children. Results showed that many “lockdown babies” may be…
Experts highlight link between hand size difference and COVID-19 severity
The difference in finger length between a person’s left and right hand may provide vital information about how ill they could get if they contract Covid-19.
Many middle-aged adults wary of taking part in studies of dementia prevention drugs
Drug companies and university-based teams are working urgently to find and test new medications that could prevent or slow the decline of brain function in older adults. But a new study suggests they’ll need to work harder to find volunteers for their clinical trials.
Patient-specific cancer tumours replicated in 3D bioprinting advance
Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumours in 3D models. The University of Bristol-led advance, published in Biofabrication, would allow clinicians to treat the models, known as spheroids, with chemotherapy drugs and radiation to help them understand an individual patient’s resistance to therapies.
Study finds high prevalence of COVID-19 and flu co-infections during 2021-2022 flu season
Researchers from the University of Missouri School of Medicine have discovered a high prevalence of COVID-19 co-infections in central Missouri during the 2021-2022 flu season, with a monthly co-infection rate as high as 48% among individuals with COVID-19.
Teens with COVID-19 knowledge reported better well-being
A pandemic survey found that adolescents who answered more COVID-19 test questions correctly also reported lower stress, anxiety and depression as well as lower loneliness and fear of missing out, also known as FOMO.
Inequality linked to differences in kids’ brain connections
Growing up in a socioeconomically disadvantaged household may have lasting effects on children’s brain development, a large new study suggests. Compared with children from more-advantaged homes and neighborhoods, children from families with fewer resources have different patterns of connections between their brain’s many regions and networks by the time they’re in upper grades of elementary school.
One socioeconomic factor stood out in the study as more important to brain development than others: the number of years of education a child’s parents have.
Ambrosia Beetles Breed and Maintain Their Own Food Fungi
Ambrosia beetles practice active agriculture: A bark beetle species breeds and cultivates food fungi in its nests and ensures that so-called weed fungi spread less.
Now we know how plants steer clear of salt
To avoid salt in soil, plants can change their root direction and grow away from saline areas.
Bridging knowledge with action: Notre Dame climate experts discuss the future of our planet
At the University of Notre Dame, climate change researchers are bringing real-world solutions to communities worldwide, providing perspective on policy issues and encouraging shifts in human behavior to face that uncertainty with resilience.
Extracellular Viscosity Linked to Cancer Spread
New research findings show how higher viscosity, or resistance to flow, of the extracellular fluid that surrounds cells enables cancer cells to migrate more rapidly from a primary tumor to other sites in the body.
Why Fish Look Down When They Swim
Just as you might look down at the sidewalk as you walk, fish look downward when they swim, a new study by a Northwestern University-led international collaboration has confirmed.
Brain Changes in Autism Are Far More Sweeping Than Previously Known
The new study finds brain-wide changes in virtually all of the 11 cortical regions analyzed, regardless of whether they are higher critical association regions – those involved in functions such as reasoning, language, social cognition and mental flexibility – or primary sensory regions.
Infants less likely to contract COVID, develop severe symptoms than other household caregivers
In one of the first studies to explore how COVID-19 specifically affects older infants, researchers from the University of Washington and at institutions at four other locations in the Western and Southern U.S. found that the number of infected people in a household was the factor most closely linked with the infant’s likelihood of being infected.
Permanent daylight saving time would reduce deer-vehicle collisions, study shows
Adopting permanent DST in the United States would reduce deer-vehicle collisions and likely prevent an estimated 36,550 deer deaths, 33 human deaths, 2,054 human injuries and $1.19 billion in costs each year. Deer-vehicle collisions would decrease under permanent DST because skies would be brighter later in the evening
American College of Rheumatology Educating Dermatologists and Nephrologists on Lupus Clinical Trials Racial Disparities
The American College of Rheumatology (ACR) has released Continuing Medical Education (CME) for dermatologists and nephrologists to help them learn more about clinical trials for lupus patients in their treatment areas and the importance of getting more of African American/Black patients enrolled.
Hackensack Meridian Health Research Institute Accelerates Discovery and Innovation in NJ’s Largest Health Network
HMHRI brings together health network expertise – for the benefit of patients
‘Fearmongering’ drives Netanyahu’s comeback in Israel
Former Israeli leader Benjamin Netanyahu is on the verge of returning to office and the country is likely to be led by one of its most conservative governments. Netanyahu’s comeback appears powered by politician Itamar Ben-Gvir and the far-right. Uriel…
Johns Hopkins Experts Available to Discuss Young Voter Turnout
National polls suggest young people are least likely to vote this election cycle. Johns Hopkins University experts are available to discuss the implications of low voter participation among young people and key election issues that could get this group to…
Three University of Maryland School of Medicine Faculty Members Honored by Baltimore Business Journal
Three University of Maryland School of Medicine physician researchers were recognized when the Baltimore Business Journal announced its Leaders in Health Care and 40 Under 40 Award winners.
New 3D model shows how cadmium exposure may affect heart development
Researchers have developed a three-dimensional model that shows how exposure to cadmium might lead to congenital heart disease.
Study: Schools’ Social Media Posts May Be Compromising Student Privacy
U.S. schools and school districts have shared an estimated 4.9 million posts that include identifiable images of students on public Facebook pages, unintentionally putting student privacy at risk, according to a new study.
MIRRI and USCCN enhance their cooperation to promote the valorization of microbial resources and innovation in biotechnology
Leading culture collection networks in the EU and the U.S. announced today the signing of a Memorandum of Understanding to enhance their cooperation to promote microbial resources and innovation in biotechnology.
Sylvester’s Sexual Health After Cancer Program Expands to Meet Needs of Women with Cancer
Kristin E. Rojas, M.D., FACS, FACOG, assistant professor of surgical oncology in the DeWitt Daughtry Department of Surgery and Sylvester Comprehensive Cancer Center at the University Miami Miller School of Medicine, realized she had struck a chord with women being…
As respiratory illnesses increase, WVU experts share information to prevent possible ‘tridemic’
Respiratory illnesses are affected the United States as winter approaches, and a “tridemic” is possible with the flu, COVID-19 and RSV.
Ahead Study Is First to Test Lecanemab to Delay or Prevent Alzheimer’s Disease Symptoms at the Stage of Preclinical Ad
The Alzheimer’s Clinical Trial Consortium (ACTC) will be presenting analyses of screening plasma and neuroimaging data from the AHEAD Study at CTAD in November.
October jobs report: Growth likely, but threats come with Fed interest increases
On Friday, the U.S. Bureau of Labor Statistics will release employment figures for the month of October. The following Cornell University experts are available for interviews. Erica Groshen, senior economics advisor, is a labor statistics expert. She was also the…
Study Reveals Additional Representation through Brain’s Somatomotor System
Article title: A third somatomotor representation in the human cerebellum Authors: Noam Saadon-Grosman, Peter A. Angeli, Lauren M. DiNicola, Randy L. Buckner From the authors: “We provide reliable evidence that the human cerebellum possesses three spatially distinct representations of the…
Researchers ID Gene and Protein Involved in Muscle Wasting, Could Lead to Targeted Treatment
Article title: Pathophysiological levels of GDF11 activate Smad2/Smad3 signaling and induce muscle atrophy in human iPSC-derived myocytes Authors: Mikako Honda, Takumi Makino, Xiaolin Zhao, Mariko Matsuto, Hidetoshi Sakurai, Yu Takahashi, Makoto Shimizu, Ryuichiro Sato, Yoshio Yamauchi From the authors: “In…
Researchers ID Pathway Involved in Inflammatory Bladder Damage in Mouse Model of Type 1 Diabetes
Article title: Diabetes causes NLRP3-dependent barrier dysfunction in mice with detrusor overactivity but not underactivity Authors: Michael R. Odom, Francis M. Hughes Jr., Huixia Jin, J. Todd Purves From the authors: “This is the first study to demonstrate that NLRP3-mediated…
A lasting impact: microplastics settling into soil
Soils with high concentrations of microplastics could experience limited water flow
Biological Sex, Heart Disease Risk Factors Can Influence Relationship between Cardiorespiratory Fitness Level and Brain Blood Flow
Article title: Influence of sex and presence of cardiovascular risk factors on relations between cardiorespiratory fitness and cerebrovascular hemodynamics Authors: Wesley K. Lefferts, Cynthia M. Weiner, Sara E. Mascone, Jacqueline A. Augustine, Kevin S. Heffernan, Elizabeth C. Lefferts From the…
Changing Hormone Levels Post-menopause Leads to Vascular Impairment in Female Mice
Article title: Cerebral arteriolar and neurovascular dysfunction after chemically induced menopause in mice Authors: Jade A. Blackwell, Josiane F. Silva, Emma M. Louis, Andrea Savu, Tally M. Largent-Milnes, Heddwen L. Brooks, Paulo W. Pires From the authors: “Together, our data…
Researchers ID a Protein that Could Help Stop Cancerous Tumor Development
Article title: Decorin evokes reversible mitochondrial depolarization in carcinoma and vascular endothelial cells Authors: Thomas Neill, Christopher Xie, Renato V. Iozzo From the authors: “In conclusion, we have delineated a molecular axis focused on delivering prodepolarization signals to the mitochondrial…
New Research on Neuronal Response to Calcium Imaging Aid Interpretation of Data without Electrophysiology Recordings
Article title: Simultaneous whole-cell patch-clamp and calcium imaging on myenteric neurons Authors: Zhiling Li, Werend Boesmans, Youcef Kazwiny, Marlene M. Hao, Pieter Vanden Berghe From the authors: “Our findings will help in the interpretation of calcium imaging data without the…
Substance in Urine May Help Determine Asthma Severity
Article title: Urinary total conjugated 3-bromotyrosine, asthma severity and exacerbation risk Authors: Zeneng Wang, Weiling Xu, Suzy A. A. Comhair, Xiaoming Fu, Zhili Shao, Rebecca Bearden, Joe G. Zein, Eugene R. Bleecker, Mario Castro, Loren C. Denlinger, John V. Fahy,…
Clear window coating could cool buildings without using energy
Demand is growing for technologies to cool buildings. Now, researchers report in ACS Energy Letters that they have used advanced computing technology and artificial intelligence to design a transparent window coating that could lower the temperature inside buildings, without expending energy.
DNA ‘Nanotransporters’ to treat cancer
Canadian chemists specializing in nanotechnology draw inspiration from nature to create molecular transporters that optimize the release of therapeutic drugs.
New Tool for Estimating People’s Total Exposure to Potentially Harmful Chemicals Is Developed
A novel metric that estimates our “burden,” or cumulative exposure, to a family of thousands of synthetic chemicals that we encounter in everyday life with potentially adverse health impacts, has been created by a team of researchers at Mount Sinai.