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UrduArticle title: Chaperone-mediated autophagy protects cardiomyocytes against hypoxic cell death Authors: Rajeshwary Ghosh, Jennifer Jason Gillaspie, Kenneth S. Campbell, J. David Symons, Sihem Boudina, James Scott Pattison From the authors: “In summary, the present study demonstrated the importance of [chaperone-mediated…
Month: July 2022
Flozin Drugs Lower Salt-Induced Hypertension, Maintain Circadian Rhythm in Rats
Article title: SGLT2 inhibition effect on salt-induced hypertension, RAAS and Na+ transport in Dahl SS rats Authors: Olha Kravtsova, Ruslan Bohovyk, Vladislav Levchenko, Oleg Palygin, Christine A. Klemens, Timo Rieg, Alexander Staruschenko From the authors: “The main findings of the…
Motherhood is equal to partner absence as a cause of economic disadvantage in single mothers
New research highlights the major impact of motherhood earning penalties on the economic prospects of single mother families.
Skin and Oral Microbiota Contribute to Blood Pressure Regulation
Article title: Beyond the gastrointestinal tract: oral and sex-specific skin microbiota are associated with hypertension in rats with genetic disparities Authors: Xue Mei, Blair Mell, Xi Cheng, Ji-Youn Yeo, Tao Yang, Nathaline Chiu, Bina Joe From the authors: “In conclusion,…
Bike Helmets: Finding the Right Fit For Your Child
Follow these tips to make sure your child’s helmet is safe. A bike helmet can literally be a lifesaver for a child—dramatically reducing the chances of a head or brain injury from a bike, scooter or skateboard accident. But did you know that a helmet has to fit right to do its job? If it’s too small, too loose, or not positioned correctly, it may not protect your child.
More dogs in the neighborhood often means less crime
If you want to find a safe neighborhood to live in, choose one where the residents trust each other – and have a lot of dogs to walk.
Global Expert Panel Identifies 5 Areas Where Machine Learning Could Enhance Health Economics and Outcomes Research
Value in Health, the official journal of ISPOR—the professional society for health economics and outcomes research, announced today the publication of new guidance for health economics and outcomes research and decision makers in the use of an important class of artificial intelligence techniques.
Study points to Armenian origins of ancient crop with aviation biofuel potential
Camelina, also known as false flax or Gold-of-Pleasure, is an ancient oilseed crop with emerging applications in the production of sustainable, low-input biofuels. Multidisciplinary research from Washington University in St. Louis is revealing the origins and uses of camelina and may help guide decisions critical to achieving its potential as a biofuel feedstock for a greener aviation industry in the future.
New Research Yields Valuable Evidence Regarding the Assessment of Health-Related Quality of Life in Children
Value in Health, the official journal of ISPOR—the professional society for health economics and outcomes research, announced today the publication of a series of articles providing new insights on measuring and valuing children’s health-related quality of life.
Céline Bonfils : Then and Now / 2012 Early Career Award Winner
At Lawrence Livermore National Laboratory, physicist Céline Bonfils studies how human activities influence climate change.
Substantial discrepancies found between estimated and measured GFR
A cross sectional study found that substantial discrepancies exist between individual estimated glomerular filtration rate (eGFR) and directly measured GFR (mGFR). Laboratory reports that provide eGFR calculations should consider including the distribution of this uncertainty. According to the authors, renaming the eGFR as a population average GFR (or paGFR) merits further discussion. The findings are published in Annals of Internal Medicine.
Interventions based on social needs may reduce hospitalizations, health care use
A randomized study of adult Medicaid patients suggests that social program-based interventions for housing, food security, and transportation may reduce inpatient admission rates by 11 percent and emergency department visits by 4 percent. However, health care savings based on these interventions may not cover the cost of social the social programs. The findings are published in Annals of Internal Medicine.
Guidelines experts present framework for developing living practice guidelines in health care
Guidelines experts reviewed existing research and conducted their own to present a framework for developing living practice guidelines in health care. The framework provides specific instruction for the planning, production, reporting, and dissemination of such guidelines and highlights the considerations specific to each of those areas in the context of a living document. The advice is published in Annals of Internal Medicine.
Scientists Discover Key to Hepatitis A Virus Replication, Show Drug Effectiveness
UNC School of Medicine scientists discovered that hepatitis A viral replication requires specific interactions between a human protein and a group of enzymes, and they used a molecule to stop replication at this key interactive step, making it impossible for the virus to infect liver cells.
These energy-packed batteries work well in extreme cold and heat
Researchers developed lithium-ion batteries that perform well at freezing cold and scorching hot temperatures, while packing a lot of energy. This could help electric cars travel farther on a single charge in the cold and reduce the need for cooling systems for the cars’ batteries in hot climates.
Large numbers cause magnitude neglect: The case of government expenditures
AbstractFour studies demonstrate that the public’s understanding of government budgetary expenditures is hampered by difficulty in representing large numerical magnitudes. Despite orders of magnitude difference between millions and billions, study participants struggle with the budgetary magnitudes of government programs. When…
Only seven percent of adults have good cardiometabolic health
Less than seven percent of the U.S. adult population has good cardiometabolic health, according to a new study. The researchers also identified large health disparities between people of different sexes, ages, races and ethnicities, and education levels.
Cleveland Clinic Performs First-In-World Full Multi-Organ Transplant to Treat Rare Appendix Cancer
Cleveland Clinic has successfully performed a first-in-the-world full multi-organ transplant to treat a patient with a rare form of appendix cancer called pseudomyxoma peritonei (PMP). Upon completion of the lifesaving transplant surgery, the patient received five digestive organs.
RUDN Engineers Show the Way to Control Satellite Formations More Effectively
To obtain information about objects on the earth’s surface and in near-Earth space, it is advisable to use not one, but several satellites. Such satellites move in different orbits, but operate as a whole. This allows us to increase the efficiency and accuracy of the obtained data but requires additional efforts to control the relative motion of satellites. RUDN engineers together with colleagues from Malaysia found a way to effectively control such formations of several satellites.
RUDN Professor Proposes Nanoporous Silicon Making Technique for Neuroprocessors
RUDN professor suggested the way to create porous silicon nanostructures strictly on a given region. This will help forming the silicon substrate with neurons or other biological objects and for example create neuroprocessors.
New NUS Centre for Hydrogen Innovations embarks on cutting-edge research to power a hydrogen economy
The National University of Singapore has established a new Centre for Hydrogen Innovations, supported by Temasek, with the aim of creating breakthrough technologies to make hydrogen commercially viable as a green energy source. The first of its kind in Southeast Asia, the new centre will develop capabilities to help reduce reliance on fossil fuels as a source of energy and will also nurture talent for a sustainable hydrogen economy.
New Method Boosts the Study of Regulation of Gene Activity
One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off.
Black Nursing Home Residents, Those Under Age 65 More Likely to Have Repeat Transfers to Hospital
Nursing homes transfer roughly 25% of their residents to the hospital at least once, at a cost of $14.3 billion to Medicare, according to a federal report by the Office of Inspector General.
Dinosaurs Took Over Amid Ice, Not Warmth, Says a New Study of Ancient Mass Extinction
Many of us know the conventional theory of how the dinosaurs died 66 million years ago: in Earth’s fiery collision with a meteorite, and a following global winter as dust and debris choked the atmosphere.
Dr. John Warner receives Gold Heart Award from the American Heart Association
A few years ago, American Heart Association leaders realized something.
While two national committees regarding quality of care for heart disease and stroke patients each served a unique purpose, there also was some overlap. That wasn’t a problem – it was an opportunity.
Mark Mascarenhas, M.D., who implanted the first dual-chamber leadless pacemakers at Jersey Shore University Medical Center, is available to speak to media
The cardiovascular team at Hackensack Meridian Jersey Shore University Medical Center recently implanted New Jersey’s first dual-chamber leadless pacemaker systems in patients, as part of Abbott’s AveirTM DR i2i clinical study. People who experience a slower-than-normal heart rate may receive…
Mining’s Effect on Fish Warrants Better Science-Based Policies
A new paper published in Science Advances synthesizes the impact of metal and coal mines on salmon and trout in northwestern North America, and highlights the need for more complete and transparent science to inform mining policy.
Hidden in Genetics: The Evolutionary Relationships of Two Groups of Ancient Invertebrates Revealed
Kamptozoa and Bryozoa are two phyla of small aquatic invertebrates that are related to animals like snails, earthworms, leeches, and ribbon worms.
The “forever chemical”, per and polyfluoroalkyl substances (PFAS), as an emerging threat to soil health
Soils are impacted globally by several anthropogenic factors, including chemical pollutants.
Dissolving implantable device relieves pain without drugs
A Northwestern University-led team of researchers has developed a small, soft, flexible implant that relieves pain on demand and without the use of drugs.
For women choosing a breast reconstruction surgeon, reputation outweighs demographics
Suppose you had to choose a surgeon to perform breast reconstruction after mastectomy for breast cancer: What would you base your decision on? For most women, factors like reviews and personal recommendations are more important than demographic factors, suggests a report in the July issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
خبير يشارك نصائح للوقاية من إصابات رياضات المضرب و”العصا”
مدينة روتشستر، ولاية مينيسوتا— النشاط أمر مفيد للجسم، إلا إن بعض الرياضات قد تكون قاسية بشكل خاص على اليدين والمعصمين. إن الألم في جانب الرسغ المقابل للإبهام – والذي يُسمى ألم الرسغ الزندي — هو أحد الأسباب الشائعة للألم المنهك لدى الرياضيين الذين يمارسون الرياضات التي تستخدم “العصي” أو رياضات المضرب، مثل: التنس، والغولف، والهوكي، واللاكروس.
New Jersey’s First Dual-Chamber Leadless Pacemakers Implanted at Jersey Shore University Medical Center
The cardiovascular team at Hackensack Meridian Jersey Shore University Medical Center recently implanted New Jersey’s first dual-chamber leadless pacemaker systems in patients, as part of Abbott’s AveirTM DR i2i clinical study.
“Soft” CRISPR May Offer a New Fix for Genetic Defects
Scientists have developed a CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new “soft” CRISPR system makes use of natural DNA repair machinery, providing a foundation for novel gene therapy strategies with the potential to cure genetic diseases.
Cleveland Clinic Researchers Shed New Light on Importance of Ecological Cellular Interactions in Targeted Therapy Resistance in Lung Cancer
New Cleveland Clinic research has uncovered key information about cellular interaction between tumor cells and normal tissue, providing better understanding of how therapeutic resistance develops. Findings published in Science Advances.
Study highlights heavy mental health burden of COVID-19 for ‘shielders’
Research from a new study suggests that health anxiety among the clinically vulnerable groups who shielded at home has risen since the first pandemic wave, despite developments in viral treatment and the roll-out of the vaccination programme.
New study reveals impact of plastic on small mammals, as four out of seven species identified as ‘plastic positive’
Researchers investigating the exposure of small mammals to plastics in England and Wales have found traces in the feces of more than half of the species examined
Capturing the onset of galaxy rotation in the early universe
As telescopes have become more advanced and powerful, astronomers have been able to detect more and more distant galaxies. These are some of the earliest galaxies to form in our universe that began to recede away from us as the universe expanded.
Birds warned of food shortages by neighbor birds change physiology and behavior to prepare
Songbirds learning from nearby birds that food supplies might be growing short respond by changing their physiology as well as their behavior, research by the Oregon State University College of Science shows.
Whales learn songs from each other in a cultural ‘deep dive’
A University of Queensland-led study has found humpback whales can learn incredibly complex songs from whales from other regions.
Adolescents more vulnerable to cannabis addiction but not other mental health risks
Adolescents are over three times more vulnerable to developing a cannabis addiction than adults, but may not be at increased risk of other mental health problems related to the drug, finds a new study led by UCL and King’s College London researchers.
COVID-19 vaccine protects people of all body weights from hospitalization and death, study of 9 million adults in England suggests
COVID-19 vaccines greatly reduced the number of cases of severe COVID-19 disease for everyone regardless of their body size, according to a new study published in The Lancet Diabetes & Endocrinology. Vaccine effectiveness was similar for those with a higher BMI and of a healthy weight, but slightly lower in the underweight group, who were also the least likely to have been vaccinated.
Mathematical Model Helps Predict Anal Cancer Risk in Persons with HIV Infection
UC San Diego researchers have created a mathematical model to help predict risk of anal cancer in persons with HIV infection and aid patients and doctors regarding screening decisions.
UAlbany Expert in Climate Change, Environmental Law Offers Insight on Supreme Court EPA Ruling
Albany, N.Y. (July 1, 2022) – The U.S. Supreme Court on Thursday limited the Environmental Protection Agency (EPA)’s authority to set climate standards for power plants. The court’s 6-3 ruling – which addressed an Obama-era regulation aimed at coal-fired power…
Cannabinoid Vaping Products, Genomic Biomarkers, a Novel In Vitro Testing System, and More in New Toxicological Sciences
Cannabinoid vaping products, genomic biomarkers to determine tumorigenic potential, and analyses of various testing assays are just a few of the article topics in the July 2022 issue of Toxicological Sciences.
Scientists find greenhouse gas warming likely cause of industrial-era sea level rise
An international team of scientists has developed an accurate record of preindustrial sea level utilizing precisely dated phreatic overgrowths on speleothems that provide a detailed history of Late Holocene sea-level change in Mallorca, Spain, an island in the western Mediterranean Sea. The results provide an unprecedented picture of sea level over the past 4,000 years, putting the preindustrial and modern global mean sea level (GMSL) histories in context.
New universal flu vaccine offers broad protection against influenza A virus infections, researchers find
A new universal flu vaccine constructed with key parts of the influenza virus offers broad cross protection against different strains and subtypes of influenza A viruses in young and aged populations, according to a new study by researchers in the Institute for Biomedical Sciences at Georgia State University.
The hawk has landed: Braking mid-air to prioritize safety over energy or speed
New research from the Oxford Flight Group using computer simulations and Hollywood-style motion capture shows how birds optimise their landing manoeuvres for an accurate descent.
Supreme Court’s decision to limit EPA oversight of CO2 emissions ‘a thinly veiled attempt to protect the coal industry,’ Notre Dame expert says
Alan Hamlet is an associate professor of civil and environmental engineering and earth sciences. His research focuses on integrated modeling of climate variability and climate change. In response to the recent Supreme Court EPA ruling, Hamlet said the following: “The…
All high-grade noninvasive bladder cancers should be considered high-risk, study suggests
Noninvasive (stage Ta) bladder cancers with “high-grade” characteristics should be considered at high risk of recurrence, concludes a study in The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.