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UrduDiscovering and engineering nanobodies with properties suitable for treating human diseases ranging from cancer to COVID-19 is a time-consuming, laborious process.
Tag: COVID -19
Decoding humans’ survival from coronaviruses
An international team of researchers co-led by the University of Adelaide and the University of Arizona has analysed the genomes of more than 2,500 modern humans from 26 worldwide populations, to better understand how humans have adapted to historical coronavirus outbreaks.
COVID-19 Vaccine Hesitancy: Dr. Vin Gupta Narrates New American Thoracic Society Video
The American Thoracic Society rolls out a new video to address vaccine hesitancy and answer common questions amid the COVID-19 pandemic.
Penn Medicine to Use $1M from City of Philadelphia for Additional Community Vaccination Clinics
Penn Medicine will continue its collaboration with the West and Southwest Philadelphia communities to operate a series of COVID-19 vaccine clinics in partnership with community organizations, faith-based institutions, restaurants, barbershops, and even professional sports teams thanks to $1 million in funding from the City of Philadelphia, in partnership with PMHCC.
Tree Pollen Carries SARS-CoV-2 Particles Farther, Facilitates Virus Spread
A study on the role of microscopic particles in virus transmission suggests pollen is nothing to sneeze at. In Physics of Fluids, researchers investigate how pollen facilitates the spread of an RNA virus like the COVID-19 virus. The study draws on cutting-edge computational approaches for analyzing fluid dynamics to mimic the pollen movement from a willow tree, a prototypical pollen emitter. Airborne pollen grains contribute to the spread of airborne viruses, especially in crowded environments.
First Wave COVID-19 Data Underestimated Pandemic Infections
Two COVID-19 pandemic curves emerged within many cities during the one-year period from March 2020 to March 2021. Oddly, the number of total daily infections reported during the first wave is much lower than that of the second, but the total number of daily deaths reported during the first wave is much higher than the second wave.
New analysis reveals link between birthdays and COVID-19 spread during the height of the pandemic
Risk of SARS-CoV-2 infection increased 30 percent for households with a recent birthday in counties with high rates of COVID-19
Findings suggest informal social gatherings such as birthday parties played role in infection spread at the height of the coronavirus pandemic
No birthday-bash infection jumps seen in areas with low rates of COVID-19
Households with children’s birthdays had greater risk of SARS-CoV-2 infection than with adult birthdays
Vaccination, previous infection, protect against COVID-19 gamma/P.1 variant in animal model
In a new study using variant virus recovered from one of the original travelers, researchers in the U.S. and Japan have found that vaccination with an mRNA vaccine induces antibody responses that would protect humans from infection with the gamma/P.1 variant.
Hackensack Meridian Doctors, Student Help Establish Way to Prioritize Surgeries During COVID-19 lockdown
The MeNTS method of prioritizing surgeries during the height of pandemic, developed by University of Chicago, helped procedures continue during time of need
‘Nanodecoy’ Therapy Binds and Neutralizes SARS-CoV-2 Virus
Nanodecoys made from human lung spheroid cells (LSCs) can bind to and neutralize SARS-CoV-2, promoting viral clearance and reducing lung injury in a macaque model of COVID-19.
University of Miami Miller School Study Shows COVID-19 mRNA Vaccines Do Not Impact Male Fertility
The Pfizer and Moderna mRNA COVID-19 vaccines is safe for male reproduction, according to a new study by University of Miami Miller School of Medicine researchers published in JAMA , the most widely circulated general medical journal in the world.
Pandemic-era crowdfunding more common, successful in affluent communities
A new University of Washington study of requests and donations to the popular crowdfunding site GoFundMe, along with Census data, shows stark inequities in where the money went and how much was donated.
In Show of COVID-19 Vaccine Confidence, 96% of America’s Ophthalmologists Already Vaccinated
The American Academy of Ophthalmology is calling on its members to continue to build confidence in COVID-19 vaccines and encourage people to get vaccinated, including their staff.
@UBuffalo biochemist @SurteesJennifer warns that the delta variant is particularly an issue for those individuals who are not vaccinated or are under vaccinated (i.e. 1 shot).
Expert: Jennifer Surtees, PhD, associate professor of biochemistry in the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo. Surtees and her colleagues at UB’s New York State Center of Excellence in Bioinformatics and Life Sciences have…
Researchers Develop More Reliable Rapid Tests for COVID-19
Researchers Develop More Reliable Rapid Tests for COVID-19
Public Release Date: 15-Jun-2021 00:00:00 US Eastern Time (24hr)
Research News Release
Contact Person: Deborah Kotz
Contact Phone: 410-706-4255
Contact E-mail: [email protected]
Journal: Nature Protocols
DOI: 10.1038/s41596-021-00546-w
Funder:
Grant Number(s):
Meeting:
Primary Keyword:
Medicine/Health
Keywords:
Medicine/Health -> Diagnostics
Medicine/Health -> Infectious/Emerging Diseases
Subtitle:
Tests Use Innovative Techniques That Improve Accuracy Rivaling Gold Standard PCR Test
Summary:
Researchers at the University of Maryland School of Medicine (UMSOM) have developed two rapid diagnostic tests for COVID-19 that are nearly as accurate as the gold-standard test currently used in laboratories. Unlike the gold standard test, which extracts RNA and uses it to amplify the DNA of the virus, these new tests can detect the presence of the virus in as little as five minutes using different methods.
SARS-CoV-2 Worldwide Replication Drives Rapid Rise and Selection of Mutations
The number of COVID-19 variants is growing rapidly, so much that the scale and scope of mutation may pose a threat to the continuing successful use of the current vaccines and therapies. The findings, by an international team that includes University of California researchers, are being published in the June edition of the peer-reviewed journal EMBO Molecular Medicine. The pace of variation of the SARS-CoV-2 virus strains makes plain the threat that rapidly evolving new strains might give rise to escape variants, capable of limiting the efficacy of vaccines, therapies, and diagnostic tests.
Southwest National Primate Research Center at Texas Biomed receives $37 million NIH grant
The Southwest National Primate Research Center (SNPRC) at Texas Biomed has been awarded more than $37 million from the National Institutes of Health to continue operations into 2026. The P51 grant, given by the NIH Office of Research Infrastructure Programs, provides essential funding to house and care for nearly 2,500 non-human primates that are part of life-science research programs at Texas Biomed and partners around the globe.
People with Health Insurance Vaccinated More Than Those Without, Survey Finds
People with health insurance are receiving the COVID-19 vaccine at a higher rate than those without insurance, despite the vaccine being free, according to a national survey from the Edward J. Bloustein School of Planning and Public Policy at Rutgers University-New Brunswick.
Live Virtual Event for June 11: New JAMA study answers whether COVID-19 vaccines can impact male fertility
This upcoming JAMA-published study examined whether the COVID-19 vaccine impacts male fertility.
Study Links COVID-19 Public Health Efforts to Dramatic Drop in COPD Hospitalizations
Public health measures designed to reduce the spread of the COVID-19 virus may have fostered a substantial side benefit: A 53 percent drop in hospital admissions for chronic obstructive pulmonary disease (COPD), likely due to a drop in circulating seasonal respiratory viruses such as influenza.
Physical activity may curb health care worker burnout
More physical activity programming could mitigate the effects of stress and improve worker mental and emotional health.
CSU Campuses Join COVID-19 College Vaccine Challenge
The CSU pledges to be a Vaccine Champion University as part of new White House effort aimed at increasing vaccinations for younger Americans.
Study Examines the Effects of COVID-19 on Human Kidney Cells
• The virus that causes COVID-19 can infect and replicate in human kidney cells, but this does not typically lead to cell death.
• Kidney cells that already have features of injury may be more easily infected and develop additional injury.
How does COVID-19 affect patients with cancer? Largest U.S. study shares first results
New findings include a significant increase in risk of death among patients who had recently had chemotherapy.
NCCN Cancer Experts Answer Questions about COVID-19 Vaccines
National Comprehensive Cancer Network’s patient information team provides a patient and caregiver version of recently-updated, evidence-based expert consensus recommendations for vaccinating people with cancer against COVID-19.
Immune Responses After COVID-19 Vaccination in Kidney Transplant Recipients and Patients on Dialysis
• A large majority of patients with kidney failure on dialysis—but not kidney transplant recipients—developed antibody responses to SARS-CoV-2 after COVID-19 vaccination.
• Vaccination also led to strong T cell responses against the virus that causes COVID-19 in all patients on dialysis, and in nearly 58% of kidney transplant recipients.
Study Examines COVID-19 Among Patients Receiving Home Dialysis
• Patients with kidney failure who are undergoing dialysis—whether at dialysis clinics or at home—face a higher risk of developing COVID-19 and a higher risk of dying from the disease.
Single-Shot COVID-19 Vaccine Generates Robust Immune Responses Against COVID-19 Variants
In a new study published in Nature, Dan Barouch, MD, PhD, Director of BIDMC’s Center for Virology and Vaccine Research, and colleagues report on the antibody and cellular immune responses generated by the Ad26.COV2.S vaccine against the original viral strain and against SARS-CoV-2 variants of concern. The team found that this vaccine induced immune responses against all the viral variants.
Common Diabetes Drug Shows Promise as Treatment for COVID-19 Lung Inflammation
Researchers identify molecular mechanism for the anti-inflammatory activity of diabetes drug metformin and, in mouse studies, say it prevents lung inflammation in animals infected with SARS-CoV-2, the virus that causes COVID-19.
Mandating vaccination could reduce voluntary compliance
A new study based on evidence from Germany and on a model of the dynamic nature of people’s resistance to COVID-19 vaccination sounds an alarm: mandating vaccination could have a substantial negative impact on voluntary compliance.
How a Global Pandemic Changed the Way We Eat and Shop
Studies being presented at NUTRITION 2021 LIVE ONLINE bring new insights into how people ate, shopped and felt about food as the COVID-19 pandemic unfolded. Studying these trends can shed light on potential lingering health impacts of the pandemic and inform responses to future emergencies.
New Research Shows Trend Toward Unhealthy Eating During Pandemic
As COVID-19 spread throughout the world, our daily routines and behaviors changed drastically. A new study of more than 2,000 people in the U.S. found that the pandemic has also affected how we eat. The authors found a decrease in the consumption of many food groups, particularly healthy foods such as vegetables and whole grains, compared to before the pandemic.
Covid-19 vaccines also protect unvaccinated family members
Researchers at the Helsinki Graduate School of Economics have found that the Pfizer-BioNTech and Moderna Covid-19 vaccines protect both vaccinated individuals and their unvaccinated adult household members against SARS-CoV-2 infections. The study, not yet peer-reviewed, used Finnish administrative datasets to examine the link between mRNA-based Covid-19 vaccines and infection risk among vaccinated individuals as well as their unvaccinated family members.
Most New Jerseyans Support Fully Reopening Public Schools in Fall, Requiring Vaccinations for Healthcare Workers, Rutgers Poll Shows
As vaccination rates increase and prospects of normal life return more than a year into the coronavirus pandemic, New Jerseyans differ on various aspects of this “new normal” and how comfortable they feel, according to the latest Rutgers-Eagleton Poll.
Increase in Advanced Breast Cancer Diagnoses During COVID-19 Pandemic
Reporting at the 2021 annual meeting of the American Society of Clinical Oncology, Kathryn A. Gold, MD, associate clinical professor at University of California San Diego School of Medicine, presented data showing a decrease in people diagnosed with early stage…
Dip your toe – or dive right in: WVU psychologists spill advice on reentering the world post-COVID
A high percentage of the population may experience “re-entry anxiety” as more people get vaccinated, guidelines are loosened and the masks come off, according to WVU psychologists.
Disparities in COVID-19 Rates among Adults with Kidney Failure in New York City
• Among adults with kidney failure undergoing hemodialysis in New York City, Black and Hispanic patients were more likely to develop symptomatic COVID-19 than White patients.
• Neighborhood-level social vulnerability factors were associated with COVID-19 incidence among White patients, but these factors did not explain racial/ethnic disparities.
Live Virtual Event for June 11: New JAMA study answers whether COVID-19 vaccines can impact (male) fertility
This upcoming JAMA-published study examined whether the COVID-19 vaccine impacts male fertility.
Study Shows Obesity May Increase Risk of Long-Term Complications of COVID-19
A Cleveland Clinic study shows that survivors of COVID-19 who have moderate or severe obesity may have a greater risk of experiencing long-term consequences of the disease, compared with patients who do not have obesity. The study was recently published online in the journal of Diabetes, Obesity and Metabolism.
About One in Six New Jerseyans Say They Won’t Get COVID-19 Vaccine
Seventy-three percent of New Jerseyans say they have received at least one dose of a COVID-19 vaccine, and while another 10 percent say they will likely roll up their sleeve for it, 16 percent remain unwilling, according to the latest Rutgers-Eagleton Poll.
Preclinical research reveals that new IgM antibodies administered intranasally to fight COVID-19 more potent than commonly used ones
A nasal therapy, built upon on the application of a new engineered IgM antibody therapy for COVID-19, was more effective than commonly used IgG antibodies at neutralizing the COVID-19 virus in animal models, according to research recently published by The University of Texas Health Science Center at Houston (UTHealth), The University of Texas Medical Branch at Galveston (UTMB Health), the University of Houston, and IGM Biosciences, Inc.
Tip Sheet: Massive unmet needs in COVID-19 treatment, osteoporosis drugs for breast cancer, new bladder cancer target — and AIDS at 40
SEATTLE — June 2, 2021 — Below are summaries of recent Fred Hutch research findings and other news. If you are covering news at the annual meeting of the American Society of Clinical Oncology (June 4-8), check out our ASCO page highlighting Fred Hutch presentations and feel free to reach out to our media team for help sourcing experts: media@fredhutch.
Top Researchers Identify Areas for Autoimmune Disease Research at AARDA-Hosted Colloquium
The American Autoimmune Related Disease Association (AARDA) hosted the 15th Noel Rose Scientific Colloquium on May 1, 2021, bringing together high-level researchers from different areas and specialties.
Study Provides New Insights on COVID-19 Risk in Patients Receiving Dialysis
• Among individuals with kidney failure who received dialysis at clinics several times each week, COVID-19 risks were higher in patients who were older, had diabetes, lived in local communities with higher COVID-19 rates, and received dialysis at clinics that served a larger number of patients.
• Risks were lower in patients who received dialysis in clinics with a higher number of available side rooms and that had mask policies for asymptomatic patients.
Researchers Discover Drug that Blocks Multiple SARS-CoV-2 Variants in Mice
A small molecule STING agonist was highly protective against the virus that causes COVID-19 and likely other coronaviruses
Results of the COLCORONA study published in The Lancet Respiratory Medicine
Colchicine could be considered as a treatment for non-hospitalized patients diagnosed with COVID-19 by PCR test and at risk of complications
Study: Cardiac MRI Effective in Detecting Asymptomatic, Symptomatic Myocarditis in Athletes
COLUMBUS, Ohio – A cardiac MRI of athletes who had COVID-19 is seven times more effective in detecting inflammation of the heart than symptom-based testing, according to a study led by researchers at The Ohio State University Wexner Medical Center and College of Medicine with 12 other Big Ten programs.
Houston Methodist and U.S. Department of Health and Human Services partner to expand access to COVID-19 monoclonal antibody treatment
Houston Methodist announced today, in partnership with the U.S. Department of Health and Human Services (HHS), that it has expanded access to COVID-19 monoclonal antibody therapy (mAb) in the Greater Houston area. The promising treatment has been shown to keep high-risk COVID-19 patients out of the hospital and reduce the likelihood of progression to severe disease.
Survey Finds Regional, Racial Divides in K-12 Remote Schooling Impact During Pandemic
More than 70% of K-12 students across the country experienced some remote schooling during the 2020-21 school year, with stark differences emerging along regional and racial lines and the worst effects on students’ social relationships, according to a new, nationally representative study conducted by Ipsos, using its KnowledgePanel, for the Tufts University Research Group on Equity in Health, Wealth and Civic Engagement.
Penn Medicine Launches Region’s First Post-COVID-19 Neurological Care Clinic
As many as one in three COVID-19 survivors experience a mental health or neurological disorder, adding to a growing body of evidence that show COVID-19 can have serious and potentially long-lasting effects on the brain. The Penn Neuro COVID Clinic aims to assess and treat long-haul COVID patients suffering from neurological symptoms.