Cedars-Sinai Guerin Children’s is building a formidable pediatric research enterprise aimed at identifying the genetic underpinnings of childhood diseases and developing novel therapies.
Tag: multiple sclerosis
Wayne State researcher receives grant from the National Multiple Sclerosis Society to explore new causes of MS
Alexander Gow, Ph.D., professor and associate director of the Center for Molecular Medicine and Genetics and professor of pediatrics and neurology at the Wayne State University School of Medicine, received an award from the National Multiple Sclerosis Society for a study into the causes of multiple sclerosis.
The grant will explore the early roots of Multiple Sclerosis (MS) in patients that Gow believes may begin years — perhaps even decades — before symptoms become apparent.
Uncovering why more Black women than ever are being diagnosed with multiple sclerosis
Women are more likely than men to get diagnosed with multiple sclerosis (MS), an incurable disease that affects the central nervous system.
Good News—MS Drugs Taken While Breastfeeding May Not Affect Child Development
Certain medications for multiple sclerosis (MS) called monoclonal antibodies, taken while breastfeeding, may not affect the development of a child during the first three years of life, according to a preliminary study released today, March 4, 2024. The study will be presented at the American Academy of Neurology’s 76th Annual Meeting taking place April 13–18, 2024, in person in Denver and online. The study examined four monoclonal antibodies for MS: natalizumab, ocrelizumab, rituximab and ofatumumab.
Research and customized care make aging with Multiple Sclerosis better
Physician scientists at The Ohio State University Wexner Medical Center and College of Medicine are studying why multiple sclerosis (MS) worsens as patients grow older. The “Aging with MS Clinic” provides complete care for older adults with MS.
Gold nanoparticles reverse brain deficits in multiple sclerosis, Parkinson’s
Results from phase two clinical trials at UT Southwestern Medical Center showed that a suspension of gold nanocrystals taken daily by patients with multiple sclerosis (MS) and Parkinson’s disease (PD) significantly reversed deficits of metabolites linked to energy activity in the brain and resulted in functional improvements.
Autoimmune disease and pregnancy
For many aspiring mothers with autoimmune disease, pregnancy can be daunting and full of unknowns.
A blood test shows MS worsening 1 to 2 years before it happens
Multiple sclerosis patients whose blood tests reveal elevated NfL, a biomarker of nerve damage, could see worsening disability one to two years later, according to a new study spearheaded by researchers at UC San Francisco.
Artificial Intelligence Models Predict Multiple Sclerosis, Detect Contaminated Lab Samples
A new artificial intelligence model can predict people’s risk of multiple sclerosis years before diagnosis, potentially enabling quicker treatment, according to research revealed today at the 2023 AACC Annual Scientific Meeting & Clinical Lab Expo.
Faster progression of multiple sclerosis associated with newly identified genetic variant
In a new study of more than 22,000 people with multiple sclerosis (MS), an international team identified for the first time a genetic variant associated with faster progression of the disease and accumulation of disability. Despite the development of effective…
Scientists identify the first genetic marker for MS severity
A study of more than 22,000 people with multiple sclerosis has discovered the first genetic variant associated with faster disease progression, which can rob patients of their mobility and independence over time.
Why women with multiple sclerosis get better when pregnant
Women suffering from the autoimmune disease multiple sclerosis temporarily get much better when pregnant. Researchers have now identified the beneficial changes naturally occurring in the immune system during pregnancy.
University of Michigan Sleep Expert Research Highlights at #SLEEP2023
June 3 marks the start of the Annual Meeting for the American Academy of Sleep Medicine and the Sleep Research Society. The Michigan Medicine Sleep Disorders Centers will be well-represented with leadership and participation in over 20 events, from oral…
‘Tipping The Balance’ Of Immune Cells from Bad to Good Reverses Multiple Sclerosis Symptoms in Mice
According to the federal government’s National Institute of Neurological Disorders and Stroke, nearly 3 million people worldwide — with almost a third in the United States — are living with multiple sclerosis (MS), a disabling neurological disease in which the body’s immune system mistakenly attacks nerves feeding information to the central nervous system (the brain and spinal cord). Although rarely fatal, MS can lead to long-term disabilities, and impair movement, muscle control, vision and cognition.
Study: Drug May Delay Earliest Symptoms of Multiple Sclerosis
A drug called teriflunomide may delay first symptoms for people whose magnetic resonance imaging (MRI) scans show signs of multiple sclerosis (MS) even though they do not yet have symptoms of the disease. The preliminary study, released April 19, 2023, will be presented at the American Academy of Neurology’s 75th Annual Meeting, being held in person in Boston and live online from April 22-27, 2023. Called radiologically isolated syndrome, the condition is diagnosed in people who do not have MS symptoms but who have abnormalities in the brain or spinal cord called lesions, similar to those seen in MS.
Genomic Analysis of Multiple Sclerosis Reveals Possible Biomarkers
A better understanding of the genetic biomarkers underpinning multiple sclerosis (MS) may lead to predictors of disease that could improve management of the condition, according to new research presented at Physiatry ’23, the Association of Academic Physiatrists (AAP) annual meeting.
Insomnia, sleep apnea contribute to reports of cognitive decline in women with multiple sclerosis
Sleep disorders such as insomnia and sleep apnea may contribute to perceived cognitive decline, including ability to follow instructions and memory, in women with multiple sclerosis. Cognitive decline affects up to 70% of people with MS.
Children at Risk of Multiple Sclerosis Often Go Undetected in Early Stages
Criteria used by neurologists to assess for multiple sclerosis (MS) in adults may fail to identify the illness in children with imaging suspicious for the disease, an oversight that could delay treatment of the disease at its earliest stages, according to a Rutgers study.
UK HealthCare neurologist working to improve access to MS treatments
Together with Multiple Sclerosis (MS) experts, biostatisticians and clinicians from across the globe, a UK HealthCare neurologist has helped compile an essential list of MS medications for patients in resource-poor settings. Jagannadha “Jay” Avasarala, M.D., Ph.D., director of the Comprehensive Care Center for MS and Neuroimmunology at the Kentucky Neuroscience Institute, currently serves as a panel member of the Multiple Sclerosis International Foundation (MSIF) and previously served as chair of the American Academy of Neurology (2020-22).
Mayo Clinic Healthcare expert explains when swallowing issues are more than an accident
Many people have experienced the discomfort of food or a beverage accidentally going to the wrong place when swallowing. But swallowing issues sometimes become chronic and may be a sign of a health condition that should be treated.
Virtual Reality Technology Could Strengthen Effects of Traditional Rehabilitation for Multiple Sclerosis
East Hanover, NJ. June 30, 2022. In a recent article, Kessler Foundation scientists advocated for the incorporation of virtual reality (VR) technology in cognitive rehabilitation research in multiple sclerosis (MS).
Brain Cell Activity Plays Critical Role in CNS Disorder Outcomes
Investigators at Cedars-Sinai have comprehensively mapped molecular activity in the brain and spinal cord that is responsible for regulating the body’s response to central nervous system (CNS) disorders such as Alzheimer’s, Huntington’s disease and spinal cord injuries.
UCI-led study finds unleashing certain T cells may lead to new treatments for multiple sclerosis
In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.
Study may show why MS patients develop progressive disability but those with related diseases do not
Did you know multiple sclerosis (MS) means multiple scars? New research shows that the brain and spinal cord scars in people with MS may offer clues to why they developprogressive disability but those with related diseases where the immune system attacks the central nervous system do not.
In a study published in Neurology, Mayo Clinic researchers and colleagues assessed if inflammation leads to permanent scarring in these three diseases:
Research Highlights from 2021 ACSM Virtual Annual Meeting: Exercise in Regenerative Medicine
The 2021 Virtual ACSM Basic Science World Congress focuses on regenerative medicine. Chaired by Marcas M. Bamman, Ph.D., FACSM, from the University of Alabama at Birmingham, this world congress brings together researchers to discuss cutting-edge science in this rapidly developing field.
Patients, Prescriptions and the COVID-19 Vaccine
As the COVID-19 vaccine becomes more readily available to people across the country, many patients living with multiple sclerosis (MS), an often debilitating autoimmune disease of the central nervous system, are questioning whether patients on certain medications should get the shot.
Research News Tip Sheet: Story Ideas From Johns Hopkins Medicine
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
Evidence of an Increased Burden of Humoral Autoimmunity in the CSF and plasma of COVID-19 Patients with Comorbid Neurologic Dysfunction
Coronavirus disease 19 (COVID-19) is the most globally impactful pandemic of the past century.
Brain microstructural and metabolic alterations detected in vivo at the onset of the first demyelinating event
Background: In early multiple sclerosis, a clearer understanding of normal-brain tissue microstructural and metabolic abnormalities will provide valuable insights into its pathophysiology. Here, we studied the brain of patients with their first demyelinating episode using neurite orientation dispersion and density…
Neutrophil granulocyte markers in cerebrospinal fluid differentiate NMOSD and anti-MOG antibody associated disease from MS in acute disease phase
Background: Neuromyelitis optica spectrum disorders (NMOSD), anti-MOG-antibody associated disease (MOGAD) and multiple sclerosis (MS) may be difficult to differentiate. Detection of antibodies (Ab) targeting AQP4 and MOG is the diagnostic gold standard for the former two diseases, but has limited…
Primary astrocytopathy has a detrimental effect on remyelination efficacy of parenchymal oligodendrocyte precursor cells
Background: Astrocytic impairment is a common feature of neuromyelitis optica and possibly also multiple sclerosis (MS) lesions and initiates even prior to demyelination. Repopulation of early active plaques with aquaporin 4-negative astrocyte precursors has been recorded, implying astrocytic loss in…
MEDIA ALERT: MSVirtual2020
The MSVirtual2020 program will continue in an Encore Program that will be held on Saturday, September 26th from 9:00 a.m. – 12:15 p.m. ET. This Encore Program will feature the Late Breaker (9-10:30 a.m. ET) and COVID-19th (10:45 a.m. – 12:15 p.m. ET) sessions.
Welcome Letter from ACTRIMS President on MSVirtual2020
It is with great pleasure that I welcome you to the 8th joint ACTRIMS-ECTRIMS conference. This conference, MSVirtual2020, is the largest conference dedicated to multiple sclerosis (MS) research and our first virtual conference.
The Facts About Multiple Sclerosis
In just the U.S. alone, more than 200 individuals are diagnosed with Multiple Sclerosis (MS) each week. However, when properly managed and controlled
with medications and lifestyle adjustments, many of the common MS symptoms like visual and sensory loss, weakness and impared cognition can be mitigated.
The 8th Joint ACTRIMS-ECTRIMS Meeting – MSVirtual2020 – To be Held September 11-13 With A Special Encore Session Featuring COVID-19 & MS and Late Breakers on September 26th
The 8th Joint ACTRIMS-ECTRIMS Meeting, the largest international conference focused on Multiple Sclerosis (MS) research, will be held in a virtual format from September 11-13, 2020, with a special encore session featuring Late-Breaking News and a COVID-19 Session on September 26.
Registered Reporters Are Invited to Three Virtual MSVirtual2020 Press Conferences Featuring: The Latest Clinical Study Outcomes, Advances in Therapeutics, Diagnostics and Technologies, and Late Breakers and COVID-19 Impact on MS Research & Patient Ca
The 8th Joint ACTRIMS-ECTRIMS meeting – the largest international conference focused on research in multiple sclerosis (MS), will be held in a virtual format from September 11-13, 2020, with a special encore session featuring Late-Breaking News and a COVID-19 Session on September 26.
Largest International Multiple Sclerosis Research Conference in September 2020
The 8th Joint ACTRIMS-ECTRIMS Meeting, the largest conference focused on Multiple Sclerosis (MS) research, will be held in a virtual format from September 11-13, 2020, with a special encore featuring Late-Breaking News and a COVID-19 Session on September 26.
Dual role discovered for molecule involved in autoimmune eye disease
The inflammatory molecule interleukin-17A (IL-17A) triggers immune cells that in turn reduce IL-17A’s pro-inflammatory activity, according to a study by National Eye Institute (NEI) researchers.
Case Western Reserve University-led team develops new approach to treat certain neurological diseases
A team led by Case Western Reserve University medical researchers has developed a potential treatment method for Pelizaeus-Merzbacher disease (PMD), a fatal neurological disorder that produces severe movement, motor and cognitive dysfunction in children. It results from genetic mutations that prevent the body from properly making myelin, the protective insulation around nerve cells.
Letter from ACTRIMS President on MSVirtual2020
I am pleased to announce that the 8th Joint ACTRIMS-ECTRIMS Meeting will be held from September 11-13, 2020, with a special encore featuring Late-Breaking News and a COVID-19 Session on September 26.
Mindfulness training shows promise for people with MS
New research suggests mindfulness training may help multiple sclerosis patients in two very different ways: regulating negative emotions and improving processing speed.
Study sheds light on fatty acid’s role in “chemobrain” and multiple sclerosis
A study led by The University of Texas MD Anderson Cancer Center has found that myelin is surprisingly dynamic, a discovery that has implications for treatment of multiple sclerosis and a type of myelin damage caused by some chemotherapy drugs, often referred to as “chemobrain.”
Multi-sensor Band Quickly and Simply Records Subtle Changes in Patients with MS
An international team of scientists, led by UC San Diego researchers, has developed a new, multi-sensor tool that measures subtle changes in multiple sclerosis patients, allowing physicians to more frequently and more quickly respond to changes in symptoms or patient condition.
Free Online Toolkit Helps People with Multiple Sclerosis Manage Symptoms
A new online program can help patients receive behavioral health care for chronic pain, fatigue and depressed mood from the comfort of their home.
Jersey Shore University Medical Center Opens MS Center, Welcomes David Duncan, M.D.
Hackensack Meridian Health Jersey Shore University Medical Center recently opened a new Multiple Sclerosis (MS) Center and welcomed MS Certified Specialist David Duncan, M.D., as director of the center.
Father’s X chromosome may yield clues to higher rates of autoimmune disease in women
UCLA scientists have discovered one reason why autoimmune diseases are more prevalent in women than in men.
Potential Genetic Markers of Multiple Sclerosis Severity
In a bid to determine factors linked to the most debilitating forms of multiple sclerosis (MS), Johns Hopkins Medicine researchers say they have identified three so-called “complement system” genes that appear to play a role in MS-caused vision loss. The researchers were able to single out these genes — known to be integral in the development of the brain and immune systems — by using DNA from MS patients along with high-tech retinal scanning.