International collaboration compares geologic repository assessment tools

Researchers from Sandia National Laboratories and partner U.S. national laboratories will compare their Geologic Disposal Safety Assessment software framework to the safety assessment software of international peers at a late-April workshop.The Sandia-led Geologic Disposal Safety Assessment framework is a computer modeling system designed to answer critical safety assessment questions about future disposal options for spent nuclear fuel deep underground and the system of tunnels, containers and possible concrete-like barriers used to keep the radioactive material contained far from the surface and water sources, said Emily Stein, a Sandia manager overseeing the development of the framework.

Vax now or vax later – what do parents think of mandatory vaccination?

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has assessed parental preference for a mandatory childhood vaccination scheme and finds that, when rating different options for a mandatory vaccination scheme, the incentives for vaccinating, and penalties for not vaccinating, were the most influential factors in parents’ decisions.

George Mason University’s Bethany Usher Elected as 2023-2024 CUR President

Dr. Bethany Usher, Associate Provost for Undergraduate Education at George Mason University in Fairfax, Virginia, has been elected to serve as president of the Council on Undergraduate Research (CUR). Usher will become president-elect on July 1, 2022, taking a seat on CUR’s Executive Board, and succeeding 2022-2023 CUR president Ruth Palmer (emeritus College of New Jersey) in the summer of 2023.

Newly Elected Representatives to CUR’s 2022-2023 Executive Board

Beth A. Cunningham, PhD (American Association of Physics Teachers), Maria Iacullo-Bird, PhD (Pace University), and Charlotte K. Simmons, PhD (University of Central Oklahoma), have been re-elected to serve as council representatives on the Council on Undergraduate Research’s (CUR) executive board.

NK cells combined with bispecific antibody showed strong response for patients with lymphoma

Researchers from The University of Texas MD Anderson Cancer Center showed that natural killer (NK) cells derived from donated umbilical cord blood, combined with a novel bispecific antibody known as AFM13 that targets CD16A and CD30, achieved effective responses in patients with pretreated and refractory CD30+ lymphoma. The study was presented today at the American Association for Cancer Research (AACR) Annual Meeting 2022.

“Lungs in a Box” Now Offered at Northwestern Medicine

Due to COVID-19 and a rapidly expanding list of conditions for which lung transplantation can be lifesaving, the need for new organs is growing. However, there’s a global shortage of donated lungs, which results in numerous deaths among patients on the waitlist. To help expand the donor pool, Northwestern Medicine is now using a device from XVIVO called XPS™ which is used for ex vivo lung perfusion (EVLP) – nicknamed “lungs in a box” – to rescue potentially viable lungs and those initially deemed “unacceptable” for transplant. Out of all solid organs, lungs have the lowest utilization, with only one in five donated lungs getting transplanted.

Melting ice caps may not shut down ocean current

Most simulations of our climate’s future may be overly sensitive to Arctic ice melt as a cause of abrupt changes in ocean circulation, according to new research led by scientists at the University of Wisconsin–Madison. Climate scientists count the Atlantic Meridional Overturning Circulation (or AMOC) among the biggest tipping points on the way to a planetary climate disaster.

Baseball legend, AI pioneer, Marine Corps commandant and comedian/actor to be honored at Tulane Commencement

Four individuals who have made major contributions in fields ranging from sports and entertainment to national defense and artificial intelligence will receive honorary degrees at Tulane University’s 2022 Commencement.

Henry “Hank” Aaron, one of baseball’s greatest players; Gen. David H. Berger, a Tulane graduate and commandant of the United States Marine Corps; Ken Jeong, a medical doctor who became one of the country’s most sought-after comedic actors and Dr. Rosalind Picard, an inventor, engineer, scientist and pioneer in artificial intelligence, will receive honorary degrees at the May 21 ceremony. Aaron will receive Tulane’s first-ever posthumous honorary degree.

Simple changes in care reduced heart exposure during lung cancer radiation treatment

A team at the University of Michigan Health Rogel Cancer Center, in partnership with the statewide Michigan Radiation Oncology Quality Consortium (MROQC) lung cancer collaborative, found that raising awareness about the risk of radiation exposure to the heart and standardizing cardiac exposure limits reduced the average dose to the heart by 15% and reduced the number of patients receiving the highest heart doses by half without minimizing tumor treatment or increasing dosage to other at-risk organs in the chest

Tacking the Mesh: It’s the Anatomy That Matters!

In a study published in the May 2022 issue of Diseases of the Colon & Rectum, investigators from the Medical University of Vienna, Austria, provide insight in the anatomical position of the mesh in relation to the sacrum during a laparoscopic procedure. They studied 18 fresh cadavers and performed laparoscopic sacral mesh fixation as surgeons would do during laparoscopic ventral mesh rectopexy.

True or false: studying work practices of professional fact-checkers

Online misinformation has developed into a critical societal threat that can lead to disastrous societal consequences. Researchers at NYU Tandon and NYU Abu Dhabi interviewed professional fact-checkers from 19 countries to gather information about the fact-checking profession, fact-checking processes and methods, the use of computation tools for fact-checking, and challenges and barriers to fact-checking. 

The study, “True or False: Studying the Work Practices of Professional Fact-Checkers,” found that most of the fact-checkers felt they have a social responsibility of correcting harmful information to provide “a service to the public,” emphasizing that they want the outcome of their work to both educate and inform the public. Some fact-checkers mentioned that they hope to contribute to an information ecosystem providing a “balanced battlefield” for the discussion of an issue, particularly during elections.

Mineral Supplement Could Stop Fatty Liver Disease Progression

Results from a preclinical study add new evidence that a multi-mineral dietary supplement known as Aquamin could be a simple and effective way to reduce the long-term health consequences of non-alcoholic fatty liver disease. Aquamin, which is derived from calcified red marine algae, is rich in calcium, magnesium and 72 other minerals and trace elements.

Cleveland Clinic-Led Trial Finds That Experimental ‘Gene Silencing’ Therapy Reduces Lipoprotein(a), an Important Risk Factor of Heart Disease, By Up To 98%

Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental “gene silencing” therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.

Findings from the “APOLLO Trial: Magnitude and Duration of Effects of a Short-interfering RNA Targeting Lipoprotein(a): A Placebo-controlled Double-blind Dose-ranging Trial” were presented today during a late-breaking science session at American College of Cardiology’s 71st Annual Scientific Session and simultaneously published online in the Journal of the American Medical Association.

Major bleeding reduced in patients having non-cardiac surgery

The drug tested, tranexamic acid (TXA), was given to patients at risk of bleeding or vascular complications. The study found that TXA did not increase deep vein clotting known as VTE, heart attack, non-hemorrhagic stroke, or other major vascular complication in the 30 days after surgery.
In the study, half of 9,535 patients in 22 countries were randomly assigned TXA, half placebo. Patients were 45 years or older (average age 69 years); 44% of them were female.

High Caffeine Consumption Disrupts Heart Rhythms in Middle-aged Rats

New research finds that excess caffeine is more likely to cause irregular heart rhythms in middle aged rats than in young adult rats. The study will be presented this week at the American Physiological Society annual meeting at Experimental Biology 2022 in Philadelphia.

Five Minutes of Daily Breath Training Improves Exercise Tolerance in Middle-aged and Older Adults

New research finds potential for high-resistance inspiratory muscle strength training to help sedentary middle-aged and older adults transition to a healthier lifestyle. The study will be presented this week at the American Physiological Society annual meeting at Experimental Biology 2022.

Exercise Improves Health Markers in Young Female Survivors of Childhood Trauma

New research shows a progressive exercise training program mitigates some physiological and psychological effects of adverse childhood experiences in otherwise healthy young women. The study will be presented at the American Physiological Society annual meeting at Experimental Biology 2022.

A Prune—Or Six—a Day May Keep Inflammation at Bay

A study in postmenopausal people suggests eating nutrient-rich prunes every day may be beneficial to bone health, reducing inflammatory factors that contribute to osteoporosis. The research will be presented this week in Philadelphia at the American Physiological Society’s (APS) annual meeting at Experimental Biology 2022.