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UrduCase Western Reserve University has established an Institute for Glial Sciences to advance research of glial cells and their critical role in the health and diseases of the nervous systems, including multiple sclerosis, Alzheimer’s, pediatric leukodystrophies, Autism spectrum disorders, Parkinson’s disease and cancer.
Tag: Alzheimber’s Disease
Timothy Huang awarded $2.6M to solve Alzheimer’s disease puzzle
With the help of a new grant from the National Institute of Health for more than $2.6 million, Assistant Professor Timothy Huang, Ph.D., will continue his research on the role of the brain’s immune cells on the risk of developing Alzheimer’s disease.
The Signs of Dementia and What Can Be Done to Stave It Off
Brent Forester, the Dr. Frances S. Arkin Chair of Psychiatry at Tufts University School of Medicine and psychiatrist-in-chief and chair of the Department of Psychiatry at Tufts Medical Center, focuses his research on geriatric psychiatry and neurocognitive disorders, such as Alzheimer’s disease and related dementias, late-life depression, and older adult bipolar disorder.
New study reveals why defense against brain corrosion declines in people with Alzheimer’s disease
A new study by researchers at Case Western Reserve University revealed that the progression of Alzheimer’s disease (AD) can be slowed by suppressing a specific protein in the brain that causes corrosion.
New research points to drug option for hair-pulling, skin-picking disorders
Treatment with the drug memantine was associated with significant improvements compared to a placebo for patients with trichotillomania and excoriation disorders.
Researchers identify biomarker for diagnosing vascular dementia
Patients with higher levels of a key molecule involved in the formation of new blood vessels were more likely to have cognitive impairment or evidence of brain injury, a consortium of academic medical centers reported.
More Steps, Moderate Physical Activity Cuts Dementia, Cognitive Impairment Risk
UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science study: senior women were less likely to develop mild cognitive impairment or dementia if they did more daily walking and moderate-to-vigorous physical activity.
Big Data Analysis Powers the Fight Against Alzheimer’s
New research findings published in Science Advances (November 2022), help explain the progression of Alzheimer-related dementia in each patient. The findings outline a biological classification system that predicts disease severity.
Chula’s Innovations for the Aging Society
As one of the countries with a rapidly increasing aging population, especially this 2022, Thailand is now becoming an ‘aging’ society and will likely become a ‘super-aging society’ by 2031. To better meet the needs and provide services to the nation’s aging society, experts from various fields at Chulalongkorn University have conducted research to produce and develop innovations for the elderly.
What if We Could Give Viruses a One-Two Punch?
Researchers at Stanford and Berkeley Lab’s Molecular Foundry have developed virus-killing molecules called peptoids. The technology could make possible an emerging category of antiviral drugs that could treat everything from herpes and COVID-19 to the common cold.
Research Highlights from 2021 ACSM Virtual Annual Meeting: Exercise in Regenerative Medicine
The 2021 Virtual ACSM Basic Science World Congress focuses on regenerative medicine. Chaired by Marcas M. Bamman, Ph.D., FACSM, from the University of Alabama at Birmingham, this world congress brings together researchers to discuss cutting-edge science in this rapidly developing field.
Case Western Reserve University-led team finds that people with dementia at higher risk for COVID-19
A study led by Case Western Reserve University researchers found that patients with dementia were at a significantly increased risk for COVID-19—and the risk was higher still for African Americans with dementia.
University of Kentucky, Penn Researchers Provide Insights into Newly Characterized Form of Dementia
Working with their colleagues at the University of Pennsylvania, researchers at the University of Kentucky have found that they can differentiate between subtypes of dementia inducing brain disease. “For the first time we created criteria that could differentiate between frontotemporal dementia (FTD) and a common Alzheimer’s ‘mimic’ called LATE disease,” explained Dr. Peter Nelson of the Sanders-Brown Center on Aging at the University of Kentucky.
NSF Grants $1.24M for Project Working to Answer a Fundamental Neuroscience Question
Neuroscientist at the University at Albany will research how different types of memories are formed and stored at different times of the day, and how they are modified by different types of cells
University of Miami Miller School Plays Pivotal Role in Securing a $15 Million National Alzheimer’s Disease Research Center
University of Miami Miller School of Medicine investigators play a pivotal role in a consortium of Florida institutions just awarded a $15 million grant to collaborate on Alzheimer’s disease research. The five-year National Institutes of Health/National Institute on Aging grant brings together top Florida researchers to focus on better understanding how to diagnose, treat, prevent, and potentially cure Alzheimer’s in diverse populations.
It’s not just Alzheimer’s disease: Sanders-Brown research highlights form of severe dementia
The long-running study on aging and brain health at the University of Kentucky’s Sanders-Brown Center on Aging Alzheimer’s Disease Center has once again resulted in important new findings – highlighting a complex and under-recognized form of dementia.
Nilotinib Appears Safe and Affects Biomarkers In Alzheimer’s Disease Clinical Trial
A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer’s disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy.
UCI-led study finds modifiable risk factors could play a role in Alzheimer’s disease
Amyloid is a key feature of Alzheimer’s disease, but the accumulation of these sticky proteins may not be the only risk factor for developing Alzheimer’s disease, according to a new study published this week. Other, modifiable risk factors, such as the amount of fats in our blood and how efficiently our bodies generate energy could also play important roles.
A happy partner leads to a healthier future
Research found that those who are optimistic contribute to the health of their partners, staving off the risk factors leading to Alzheimer’s disease, dementia and cognitive decline as they grow old together.
Are bigger brains better?
When it comes to certain parts of the brain, bigger doesn’t necessarily equate to better memory. According to a new study led by Michigan State University, a larger hippocampus, a curved, seahorse-shaped structure embedded deep in the brain, does not always reliably predict learning and memory abilities in older adults.
Pathogenic Alzheimer’s disease cascade is activated by faulty norepinephrine signaling
Preclinical research has revealed a key missing piece of the Alzheimer’s disease puzzle. That allowed proof-of-concept experiments — using an existing drug — that dramatically reduced Alzheimer’s pathology and symptoms in mouse models, potentially offering an immediate treatment for this disease.
Scientists identify protein associated with ovarian cancer that exacerbates neurodegeneration in Alzheimer’s
Houston Methodist scientists identified a protein found in ovarian cancer that may contribute to declining brain function and Alzheimer’s disease, by combining computational methods and lab research.
Can low-dose radiation therapy successfully treat Alzheimer’s disease?
A team from the Beaumont Research Institute believes low-dose radiation might be a promising treatment for Alzheimer’s disease. The researchers are now seeking patients with Alzheimer’s disease for the study.
Predicting vulnerability to Alzheimer’s disease and delirium
A paper published today in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, researchers at Beth Israel Deaconess Medical Center (BIDMC) shed new light on a genetic risk factor for Alzheimer’s disease that may indirectly influence patients’ risk of postoperative delirium.
Key Alzheimer’s gene acts differently in non-Europeans
A gene called apolipoprotein E (APOE), long implicated in Alzheimer’s disease, has two variants that act differently among Caribbean Hispanics depending on the ancestral origin, according to a study published in Alzheimer’s and Dementia, the journal of the Alzheimer’s Association.
U.S. Health and Human Services Secretary Names María Ordóñez to Alzheimer’s Council
The advisory council is made up of federal and non-federal members who serve overlapping four-year terms. As a new member, Ordóñez brings the perspectives of Hispanic and Latino Americans and providers of long-term services and support.
Study identifies brain injury as a cause of dementia in some older adults
A UCLA-led study finds that, with the use of MRI scans, it is possible to distinguish between memory loss caused by Alzheimer’s disease and traumatic brain injury.
Combination of More Hospitalizations and Brain Pathologies Linked to Faster Cognitive Decline
Older people who experienced more hospitalizations and also had more Alzheimer’s pathology in their brain experienced the fastest rates of cognitive decline, according to study results published in the October 15 online issue of the Annals of Neurology.
New study to examine if sleep problems contribute to cognitive decline and Alzheimer’s
Everybody knows sleep is good for your body. It may be good for your mind, too.
That’s what scientists at Wake Forest School of Medicine will attempt to determine thanks to a $5.3 million grant from the National Institute on Aging, part of the National Institutes of Health.
Link between brain immune cells and Alzheimer’s disease development identified
Irvine, Calif., Aug. 21, 2019 — Scientists from the University of California, Irvine School of Biological Sciences have discovered how to forestall Alzheimer’s disease in a laboratory setting, a finding that could one day help in devising targeted drugs that prevent it. The researchers found that by removing brain immune cells known as microglia from rodent models of Alzheimer’s disease, beta-amyloid plaques – the hallmark pathology of AD – never formed.