UK HealthCare, Community Leaders Celebrate Opening of New Sanders-Brown Clinic

Today (July 25), UK HealthCare and community leaders celebrated the full opening of the Sanders-Brown Memory Clinic at Turfland. The new, larger clinic replaces the former Sanders-Brown facilities along North Broadway in Lexington.

The world looks to The University of Kentucky’s Sanders-Brown Center on Aging for answers to the mysteries of dementia, and the elderly rely on them for help in charting their path to a healthy and vigorous senior lifestyle. After outgrowing their old space, leaders at UK decided it was time that Sanders-Brown’s home for clinical research and patient care reflects their reputation — building them a new home on UK HealthCare’s Turfland Campus.

Recent Study Indicates High Prevalence of Recently Defined Non-Alzheimer’s Dementia

Researchers from the University of Kentucky’s Sanders-Brown Center on Aging say a paper recently published in Acta Neuropathologica is the most definitive assessment yet of the prevalence of a form of dementia classified in 2019 and now known as LATE. The results show that the prevalence of brain changes from LATE may be roughly 40% in older adults and as high as 50% in people with Alzheimer’s disease.

University of Kentucky’s Sanders-Brown Receives Continued Funding to Research Vascular Cognitive Impairment and Dementia Biomarkers

Researchers at the University of Kentucky’s Sanders-Brown Center on Aging recently received a five-year grant renewal of their MarkVCID program from the National Institutes of Health (NIH). The award total is more than $6 million.

Recent Study Identifies 11 Candidate Genetic Variants for Alzheimer’s Disease

A recently published study co-authored by University of Kentucky Sanders-Brown Center on Aging researcher Justin Miller, Ph.D., identifies 11 rare candidate variants for Alzheimer’s disease. Researchers found 19 different families in Utah that suffered from Alzheimer’s disease more frequently than what is considered normal.

Sanders-Brown Study Leads to Potential for a New Treatment Approach to Alzheimer’s Disease

The paper explains that current therapeutic approaches to the treatment of Alzheimer’s disease focus on the major pathological hallmarks of the disease which are amyloid plaques and neurofibrillary tangles. They are the requirements for a diagnosis of Alzheimer’s disease. However, the authors say there has been an explosion of genetic data suggesting the risk for sporadic Alzheimer’s disease is driven by several other factors including neuroinflammation, membrane turnover and storage, and lipid metabolism.

University of Kentucky, Penn Researchers Provide Insights into Newly Characterized Form of Dementia

Working with their colleagues at the University of Pennsylvania, researchers at the University of Kentucky have found that they can differentiate between subtypes of dementia inducing brain disease. “For the first time we created criteria that could differentiate between frontotemporal dementia (FTD) and a common Alzheimer’s ‘mimic’ called LATE disease,” explained Dr. Peter Nelson of the Sanders-Brown Center on Aging at the University of Kentucky.

Important Dementia Studies Continuing at UK Despite Ongoing COVID-19 Pandemic

The COVID-19 pandemic brought many things to a screeching halt and continues to impact our daily lives. However, important research at the University of Kentucky’s Sanders-Brown Center on Aging (SBCoA) is continuing under extreme caution and deep dedication.

A monumental study in the field of dementia research is set to get underway in the coming weeks at UK.

University of Kentucky’s Sanders-Brown Center on Aging Facilitates First Participant in Worldwide Drug Study

Researchers at the University of Kentucky’s Sanders-Brown Center on Aging (SBCoA) recently screened the first participant in the world for what is known as the AHEAD 3-45 study. This work is looking at a study medication, BAN2401, to determine if it can help prevent worsening memory and thinking among individuals who might be at risk for future decline. They are hoping this study finds that BAN2401 does just that and will ultimately help prevent Alzheimer’s disease.

It’s not just Alzheimer’s disease: Sanders-Brown research highlights form of severe dementia

The long-running study on aging and brain health at the University of Kentucky’s Sanders-Brown Center on Aging Alzheimer’s Disease Center has once again resulted in important new findings – highlighting a complex and under-recognized form of dementia.