LJI scientists develop new method to match genes to their molecular ‘switches’

LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have developed a new computational method for linking molecular marks on our DNA to gene activity. Their work may help researchers connect genes to the molecular “switches” that turn them on or off. This research, published in Genome Biology, is an important step toward harnessing machine learning approaches to better understand links between gene expression and disease development.

FASEB Announces 2024 Howard Garrison Advocacy Fellowship

The Federation of American Societies for Experimental Biology is now accepting applications for the 2024 Howard Garrison Advocacy Fellowship. This opportunity is open to biological and biomedical researchers in all career stages who wish to engage in collaborative exploration of science advocacy and communications.

Retrospective Study Based on Electronic Health Records Finds Popular Diabetes and Weight-Loss Drugs Associated with Reduction in Incidence and Recurrence of Alcohol-Use Disorder by at Least Half

A new study by researchers at the Case Western Reserve University School of Medicine reveals that the popular diabetes and weight-loss drugs Wegovy and Ozempic are linked to reduced incidence and recurrence of alcohol abuse or dependence.

Endocrine Society Guideline recommends healthy adults under the age of 75 take the recommended daily allowance of vitamin D

Healthy adults under the age of 75 are unlikely to benefit from taking more than the daily intake of vitamin D recommended by the Institutes of Medicine (IOM) and do not require testing for vitamin D levels, according to a new Clinical Practice Guideline issued today by the Endocrine Society.

From lab to life: 3D bioprinting unveils new horizons in biomedical applications

A cutting-edge review explores the convergence of three-dimensional (3D) printing and peptide self-assembly, unveiling a new era in biomanufacturing. This technology paves the way for creating sophisticated biomaterials, advancing the fields of tissue engineering and regenerative medicine.

AI goes underwater: transforming coral reef conservation with cutting-edge image analysis

In an era where coral reef ecosystems worldwide are under significant threat, the ability to accurately monitor and assess their health is more crucial than ever. This latest research introduces sophisticated deep learning models to enhance the precision and speed of coral reef imaging analyses, paving the way for more effective conservation strategies.

Fewer than 1 in 4 patients receive dietary counseling after a heart attack

Although diet is the leading contributor to premature death from heart disease in the United States, fewer than one-quarter of people who undergo major heart events receive dietary counseling in the aftermath, a study finds. The reason for such a low rate, researchers suggest, may be a lack of time for providing the counseling or expertise in this area by clinicians.

Mapping soil health: new index enhances soil organic carbon prediction

A cutting-edge machine learning model has been developed to predict soil organic carbon (SOC) levels, a critical factor for soil health and crop productivity. The innovative approach utilizes hyperspectral data to identify key spectral bands, offering a more precise and efficient method for assessing soil quality and supporting sustainable agricultural practices.

هل يزيد الصيام المتقطع من خطر الإصابة بأمراض القلب؟

استخدم الناس الصيام المتقطع لسنوات من أجل فقدان الوزن غير المرغوب فيه، بينما يصوم آخرون لأسباب دينية. يعد هذا الاتجاه الغذائي الشائع بين الأنظمة الغذائية آمنًا بشكل عام، لكن بعض الدراسات تشير إلى أن تناول الطعام المقيد بالوقت قد يسبب مشاكل في القلب.

Groundbreaking Progress in Quantum Physics: How Quantum Field Theories Decay and Fission

An international research team around Marcus Sperling, a researcher at the Faculty of Physics, University of Vienna, has sparked interest in the scientific community with pioneering results in quantum physics: In their current study, the researchers reinterpret the Higgs mechanism, which gives elementary particles mass and triggers phase transitions, using the concept of “magnetic quivers.”

Telemedicine may increase endocrinology care access for under-resourced patients with diabetes and heart disease

Widespread availability of telemedicine during the pandemic led to more equitable access to endocrinology care for patients with type 2 diabetes and heart disease, according to a study being presented Monday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

Two medication classes reduced cardiovascular and liver events in people with type 2 diabetes

GLP-1 receptor agonists (GLP-1s) and SGLT-2 inhibitors lower the risk of major cardiovascular events like heart attacks and severe liver complications compared to other diabetes treatments, according to data being presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

HKIAS Senior Fellow Professor Nieng Yan wins the L’Oréal-UNESCO For Women in Science International Award 2024

The Hong Kong Institute for Advanced Study (HKIAS) of City University of Hong Kong congratulates our Senior Fellow, Professor Nieng Yan, on winning the prestigious L’Oréal-UNESCO For Women in Science International Award 2024. This recognition celebrate Professor Yan’s exceptional contributions to structural biology.

Metformin may be as safe as insulin during pregnancy, 11-year data shows

Metformin is safe to use during pregnancy to manage diabetes, with no long-term adverse effects on the children born and their mothers for at least 11 years after childbirth, according to research presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass. This is the first study to look at longer term effects of metformin use during pregnancy.

Persons of nonbinary gender may desire lower-dose testosterone treatment than guidelines recommend

Among transgender and gender-diverse adults whose gender identity is nonbinary—not exclusively male or female—and who choose low-dose hormone treatment, most prefer to continue testosterone therapy at lower-than-recommended doses after at least six months of treatment, a new study finds. The study will be presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

Thyroid eye disease patients report maintained improvement 2 years after teprotumumab infusions

Most patients with thyroid eye disease treated with teprotumumab didn’t require additional treatments nearly 2 years later, according to industry-supported research being presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass., and published in the journal Thyroid.

Study finds potentially treatable factors to improve symptoms in men stopping illicit steroids

Men who illicitly used steroids to boost muscle size and physical performance and have stopped in the past year have impaired sexual function compared with men currently using steroids, according to a study being presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

Hot flashes in menopausal women may signal increased risk for heart and metabolic issues

Women experiencing moderate-to-severe vasomotor symptoms face a three times greater risk for metabolic-dysfunction-associated steatotic liver disease (MASLD) compared to those with mild symptom severity, according to research being presented Monday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

Almost 20% of breast cancer survivors may experience excess weight gain

Almost one out of five breast cancer survivors may experience weight gain of more than 10%, suggests a study presented Monday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass. A number of factors are associated with excessive weight gain, the researchers found.

ASCO: New ‘Armored’ CAR produces significant responses in patients whose cancers don’t respond to current CAR T cell therapies

A new “armored” form of CAR T cell therapy may be able to help patients with non-Hodgkin lymphoma whose cancers do not respond to currently available CAR T cell therapies. The Phase I clinical trial was presented at the 2024 ASCO Annual Meeting.

Anti-obesity medication tirzepatide remains effective even for those with diabetes and other complications

Having medical conditions linked to obesity does not impact the total weight loss achieved with the anti-obesity medication tirzepatide, according to an industry-supported study being presented Saturday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

People with well-controlled, long-duration type 1 diabetes may still face high risk of heart disease

People who have had type 1 diabetes for more than 50 years without kidney complications may still be at substantial risk for heart disease, despite excellent control of blood pressure, cholesterol and blood sugar levels, according to a study presented Saturday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

Asian patients more likely to develop type 2 diabetes 1 year after prediabetes diagnosis compared to white and Black patients

One year after a prediabetes diagnosis, Asians were more likely to develop diabetes mellitus whereas Black patients were more likely to remain in prediabetes range, highlighting racial disparities in diabetes prevention, according to data presented at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

Childhood sedentariness may cause premature liver damage in young adulthood

Children who are sedentary for more than six waking hours a day have a significantly increased risk of severe fatty liver disease and liver cirrhosis by young adulthood, a new study finds. The research findings will be presented Saturday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass and published in Nature’s npj Gut and Liver.