Experts Go All In when CEBAF Is in Trouble

What happens when a unique research machine breaks? The question isn’t academic. In April, sensors showed that a vacuum seal in Jefferson Lab’s Continuous Electron Beam Accelerator Facility had failed in a critical area of the injector – the chopper – where electrons are sorted by large copper cavities and directed for experiments. Without that vacuum seal, outside air we breathe will enter those cavities, contaminating the system and effectively crippling accelerator operations. An ad hoc team of experts from the accelerator and engineering divisions assembled to diagnose the situation and figure out how to fix it.

Sanders-Brown director receives funding to advance work on potential drug

Linda J. Van Eldik, Ph.D., director of the University of Kentucky Sanders-Brown Center on Aging, is part of a $1.5 million grant to help further research into a possible treatment for Alzheimer’s disease. A four-year grant from the National Institute on Aging of the National Institutes of Health to Northwestern University includes a $611,676 subaward to UK. Van Eldik, the Dr. E. Vernon Smith and Eloise C. Smith Alzheimer’s Research Endowed Chair, serves as principal investigator on UK’s award.

Hyperactivation of the Immune System May Cause Post-COVID Syndromes

Investigators at Cedars-Sinai have proposed a theory for how SARS-CoV-2, the virus that causes COVID-19, infects the body. Their hypothesis, published in Frontiers in Immunology, could explain why some people still have symptoms long after the initial infection.

خبير من مايو كلينك للرعاية الصحية يشارك مؤشرات فشل القلب التي قد يجهلها الأشخاص ذوي عوامل الخطر

قد يبدو أن فشل القلب من أمراض التقدم في العمر، إلا إنه يمكن أن يصيب المرء في أي وقت خلال حياته. وفي كثير من الحالات، يمكن الوقاية منه أو علاجه. في هذا المقال  تشرح قوسية وامل، دكتور الطب، الحاصلة على الدكتوراه، طبيبة القلب في مايو كلينك للرعاية الصحية في لندن، عوامل الخطر، والأعراض التي قد يجهلها الناس وكيفية علاج فشل القلب. 

Study identifies new dementia risk genes through novel testing approach

A new UCLA-led study has identified multiple new risk genes for Alzheimer’s disease and a rare, related brain disorder by using a combination of new testing methods allowing for mass screening of genetic variants in a single experiment. 

Department of Energy Announces $8 Million for Research on Climate and Earth System Model Development and Analysis

Today, the U.S. Department of Energy (DOE) announced $8 million in funding for 10 projects in Earth and environmental system modeling research. Awards will focus on further development of DOE’s flagship Energy Exascale Earth System Model (E3SM) and studies that improve the predictive understanding of the climate and Earth system.

Q&A: Advice for a Healthy, Stress-Free Return to School

For the past two-plus years, the COVID-19 pandemic has disrupted children’s education and frustrated parents. Today, with the back-to-school season in full swing, Suzanne Silverstein, MA, ART, founding director of Cedars-Sinai Share & Care, and Rose Bisellach, RN, nurse manager in the Providence Cedars-Sinai Tarzana Medical Center Emergency Room, give their best advice for starting a successful school year.

COVID OUT clinical trial suggests metformin effective at reducing odds of serious outcomes for COVID-19 patients seeking early treatment

Published in the New England Journal of Medicine, researchers — led by the University of Minnesota Medical School and School of Public Health — have found that metformin, a commonly prescribed diabetes medication, lowers the odds of emergency department visits, hospitalizations, or death due to COVID-19 by over 40 percent; and over 50 percent if prescribed early in onset of symptoms.

Resultados sin precedentes de HL Tau alcanzados por ALMA en 2014 superan las 1000 citaciones en menos de una década

Los datos observacionales sin precedentes de HL Tau obtenidos por el Atacama Large Millimeter/submillimeter Array (ALMA) en 2014 han sido citados en más de mil estudios científicos en los últimos 7 años y medio. Ello ha permitido que la comunidad astronómica logre importantes avances en el estudio de la formación de planetas.El hito se produce cuando los ingenieros del Observatorio Nacional de Radioastronomía (NRAO) de la Fundación Nacional de Ciencias de EE. UU. se embarcan en ambiciosas actualizaciones de los receptores responsables de la claridad de las observaciones iniciales.

ALMA’s 2014 Ground-Breaking HL Tau Results Have Appeared in Over 1,000 Scientific Papers in Less Than a Decade

Ground-breaking 2014 HL Tau observational data from the Atacama Large Millimeter/submillimeter Array (ALMA) has been cited in more than 1,000 scientific studies in the past 7.5 years, aiding in major breakthroughs in scientists’ understanding of planet formation. The milestone comes as engineers at the U.S. National Science Foundation’s National Radio Astronomy Observatory (NRAO) embark on ambitious upgrades to the receivers responsible for the clarity of initial observations.

New Transitional Care Clinical Pathway Improves Health Equity

People with multiple chronic conditions require complex care management and often experience significant challenges when transitioning from hospital to home. This is especially true for people insured by Medicaid who are disproportionately Black, Indigenous, People of Color (BIPOC) and experience higher chronic disease burdens and adverse outcomes following hospitalization. For them, comprehensive transitional care support is a paramount, yet often absent aspect of care delivery that may result in health inequities.

Study First to Explore ‘Walking’ Sharks on the Move in Early Life Stages

A newly-discovered walking shark that breaks all of the rules for survival is the focus of a first-of-its-kind study that examined differences in walking and swimming in neonate (newly-hatched) and juvenile walking sharks. Despite dissimilarities in body shapes – neonates have bulging bellies and juveniles are slender – the three aquatic gaits they use (slow-to-medium walking, fast-walking and swimming) did not differ. Kinematics between neonate and juvenile epaulette sharks did not alter during development.

Particle Physicists Lay Out Future Goals at ‘Snowmass’ Meeting

With a picturesque backdrop of Mt. Rainier, particle physicists from across the United States gathered in Seattle (with more tuning in virtually) to assess the most important science opportunities in their field over the next decade. The Particle Physics Community Planning Exercise was held July 17-26, 2022, at the University of Washington.

Key Mechanisms of Airway Relaxation in Asthma Revealed in New Study

Many therapeutics for asthma and other obstructive lung diseases target the β2-adrenergic receptor (β2AR), a G protein-coupled receptor (GPCR) that rapidly supports airway relaxation when stimulated. Yet, overuse of these agents is associated with adverse health outcomes, including death, which has limited their utility as frontline therapies. Now, a mouse model study published in today’s issue of Molecular Cell, from investigators at University Hospitals (UH) and Case Western Reserve University, identifies a novel strategy to isolate the beneficial effects of β2AR stimulation. This suggests a new therapeutic approach to airway diseases as well as numerous other conditions involving the aberrant function of GPCRs.

New Guidelines from ASE Set Standards to Perform Transesophageal Echocardiographic Screening for Structural Heart Interventions

New guidelines published this year by the American Society of Echocardiography (ASE), Standards for the Performance of Transesophageal Echocardiographic Screening for Structural Heart Intervention, provide a unique teaching resource for interventional cardiologists, a growing group of heart specialists who perform echocardiography.

أسئلة وأجوبة مايو كلينك: نصائح لتقليل خطر التعرض لفقدان السمع

السادة الأعزاء في مايو كلينك: لقد أدركت مؤخرًا أنني غالبًا ما أطلب من الناس تكرار كلامهم، وأحتاج إلى رفع مستوى صوت التلفاز أعلى من ذي قبل. كيف أعرف إذا ما كنتُ أعاني من فقدان السمع؟ أبلغ من العمر 46 عامًا. ألستُ صغيرًا جدًا على فقدان السمع؟ هل يمكنني اتخاذ خطوات لمنع فقدان السمع في المستقبل؟