Brentuximab vedotina puede mejorar la supervivencia general en pacientes con linfoma de Hodgkin

Un estudio dirigido por los científicos del Centro Oncológico Integral de Mayo Clinic descubrió que la adición de brentuximab vedotina a la quimioterapia estándar mejora la supervivencia general de los pacientes con linfoma de Hodgkin, comparado con la administración de solo la quimioterapia estándar.

Modified bladder cancer treatment shows promise in animal studies

A modified tuberculosis (TB) vaccine developed at Texas Biomed could help treat a form of bladder cancer, called non-muscle invasive bladder cancer, without strong side effects. Results in mouse models and human cells show promising results and pave the way for human clinical trials. The research, conducted in close collaboration with UT Health San Antonio, was published online in June in the journal Cancer Immunology, Immunotherapy.

Medicamento brentuximab vedotina pode melhorar a sobrevida geral de pacientes com linfoma de Hodgkin

Um estudo conduzido por pesquisadores do Centro de Câncer da Mayo Clinic descobriu que adicionar o brentuximab vedotina ao tratamento quimioterápico padrão aumenta a taxa geral de sobrevida de pacientes com linfoma de Hodgkin, em comparação com o padrão de tratamento atual que usa somente a quimioterapia.

دواء برنتوكسيماب فيدوتين قد يحسّن فرص النجاة لدى مرضى لمفومة هودجكيِن عموماً

وجدت دراسة قادها باحثون من مركز مايو كلينك الشامل للسرطان أن إضافة دواء برنتوكسيماب فيدوتين إلى العلاج الكيميائي المعتاد يحسّن فرص النجاة لدى مرضى لمفومة هودجكيِن بشكل عام، بالمقارنة مع المعيار الحالي للعلاج الكيميائي وحده.

Children’s Hospital Los Angeles Experts Present on the Latest in Pediatric and Congenital Cardiovascular Diseases at 25th Annual Cardiology 2022 Conference

Twenty-six Children’s Hospital Los Angeles physicians, nurses and leaders will serve as presenters at the 25th Annual Cardiology 2022 Conference, themed “The New Normal: Transformation in Pediatric & Congenital Heart Disease.”

WVU celebrates grand opening of Reynolds Hall with building’s namesake

West Virginia University will hold a grand opening ceremony to celebrate Reynolds Hall, the futuristic 186,000-square-foot business complex on Morgantown’s Waterfront made possible through the generosity of Bob and Laura Reynolds. The building is the new home of the John Chambers College of Business and Economics and its 3,700 students.

Scientists are unravelling the mystery of the arrow of time

The flow of time from the past to the future is a central feature of how we experience the world. But precisely how this phenomenon, known as the arrow of time, arises from the microscopic interactions among particles and cells is a mystery—one that researchers at the CUNY Graduate Center Initiative for the Theoretical Sciences (ITS) are helping to unravel with the publication of a new paper in the journal Physical Review Letters.

Myocarditis risk significantly higher after COVID-19 infection vs. after a COVID-19 vaccine

In a detailed analysis of nearly 43 million people, ages 13 and older, who received at least one dose of a COVID-19 vaccine in England, the risk of myocarditis in unvaccinated individuals after COVID-19 infection was at least 11 times higher compared to people who developed myocarditis after receiving a COVID-19 vaccine or booster dose between December 1, 2020 and December 15, 2021, according to new research published today in the American Heart Association’s flagship, peer-reviewed journal Circulation.

Smidt Heart Institute Experts to Present Innovative Research Findings at European Society of Cardiology Congress 2022

Experts from the Smidt Heart Institute at Cedars-Sinai, home to California’s top-ranked cardiology and heart surgery programs, will present an array of innovative research—including late-breaking science—during the European Society of Cardiology Congress 2022, taking place in person and virtually Aug. 26-29.

A person’s true feelings can be revealed in language patterns

What someone says out loud about a group of people and how they actually feel about them aren’t always the same thing, but a person’s true sentiments about other groups of people can be revealed by the language patterns they use in describing their feelings.
That’s one of the key findings from a new study by David Markowitz, an assistant professor in the University of Oregon’s School of Journalism and Communication.

Additional Antibody Mediated Prevention (AMP) trials data published in Nature Medicine

An embargoed study published in the Aug. 22, 2022 issue of Nature Medicine identifies a new biomarker that appears effective as a surrogate endpoint to reliably predict the ability of broadly neutralizing monoclonal antibodies to prevent acquisition of HIV-1, the most common type of the virus that causes AIDS. Broadly neutralizing antibodies (bnAbs) are defined by their ability to neutralize multiple genetically distinct viral strains.

Study offers insights into how pancreatic cancer develops

A detailed analysis of pancreatic cancer by researchers at Washington University School of Medicine in St. Louis has revealed details of two key transition points in the development of these tumors — the shift from normal cells to precancerous cells, and the change from precancerous to cancerous cells. Understanding these transitions will help lead to the development of novel therapies.

People with Certain Personality Traits are Less Likely to Mature Out of Hazardous Substance Use, Study Suggests

The typical rise and fall of alcohol and cannabis consumption from late adolescence into adulthood does not hold for people with certain personality traits, a new study suggests. Among individuals who used both alcohol and cannabis, those with high impulsivity as adolescents showed a different developmental trajectory from their peers, according to a study in Alcoholism: Clinical & Experimental Research — the first to assess co-use of the two substances well into adulthood. Alcohol and cannabis are the two most frequently used psychotropic drugs in the US. High use is associated with negative health outcomes, particularly when the two substances are used concurrently or simultaneously. Little is known about the developmental course of alcohol and cannabis co-use into adulthood and whether it is influenced by sensation seeking and reduced conscientiousness, markers of disinhibition associated with hazardous substance use. Researchers at Arizona State University explored whether those pe

New Study Shows Growth in Billing of Radiology Services by Non-Physician Providers in Radiology Practices

A study by the Harvey L. Neiman Health Policy Institute conducted a detailed review of clinical services billed to Medicare by non-physician providers (NPPs) employed by radiology practices. The study, published in the Journal of the American College of Radiology, was based on Centers for Medicare and Medicaid Services databases of doctors and clinicians who participated in Medicare.

The increase in funding for the IRS is not going create an army of agents that will come after you

The Inflation Reduction Act includes $79 billion for the IRS. Many political figures are reacting incredulously to this long-sought budget increase. The Fox News host Brian Kilmeade has warned his viewers that “Joe Biden’s new army” of armed IRS agents could “hunt down and kill middle-class taxpayers that don’t pay enough”.

Caterpillar-like bacteria crawling in our mouth

Likely to survive in the oral cavity, bacteria evolved to divide along their longitudinal axis without parting from one another. A research team co-led by environmental cell biologist Silvia Bulgheresi from the University of Vienna and microbial geneticist Frédéric Veyrier from the Institut national de la recherche scientifique (INRS) just published their new insights in Nature Communications. In their work, they de-scribed the division mode of these caterpillar-like bacteria and their evolution from a rod-shaped ancestor. They propose to establish Neisseriaceae oral bacteria as new model organisms that could help pinpoint new antimicrobial targets.

Drinking to Manage Physical Pain Results in Perceived Relief, Increasing Vulnerability to Dangerous Alcohol Use

People who self-medicate pain with alcohol may be vulnerable to hazardous drinking, with their experience of pain relief a potentially powerful driver of alcohol consumption, a new study suggests. Both pain and dangerous alcohol use are major public health issues. Each affects millions of US adults and costs hundreds of billions of dollars annually in health care and lost productivity. Recent studies have demonstrated a strong correlation between pain and alcohol use; people with chronic pain are more likely than others to report heavy drinking, and those with alcohol use disorder (AUD) are more likely to report chronic pain. Alcohol has known analgesic effects. Evidence of shared neural mechanisms underlying chronic pain and substance misuse suggest alcohol’s pain-relieving capacity might be influenced by individuals’ experience of chronic pain. Better understanding the relationship between chronic pain and alcohol use could inform improved prevention and treatment approaches. For the