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UrduLJI research shows that a “slow delivery, escalating dose” vaccination strategy can prompt B cells to spend months mutating and evolving their pathogen-fighting antibodies.
Tag: Infectious Disease
University Hospitals Chosen as Site for United States Flu Vaccine Effectiveness Network
The Center for Disease Control’s National Center for Immunization and Respiratory Diseases has awarded University Hospitals of Cleveland a sizable grant to support its assignment as a study site in the United States Flu Vaccine Effectiveness Network.
How human cells become Zika virus factories
Scientists solve mystery of how Zika virus targets key immune cell. New finding shed light on how to stop virus from spreading.
Tulane working on test to predict COVID-19 complications
An interdisciplinary team of doctors and engineers are working to develop a diagnostic test to detect severe COVID-19 complications.
Cancer and HIV
Sylvester Comprehensive Cancer Center researcher Emmanuel Thomas, M.D., Ph.D., F.A.A.S.L.D., has been appointed to the National Institutes of Health’s (NIH) Coinfections and HIV Associated Cancers (HCAC) study section.
How Wastewater Surveillance Can Mitigate Monkeypox Spread: Expert Available
Just when it seemed like we could sit back and breathe a sigh of relief from declining COVID-19 rates in Nevada, another virus started making headlines: Monkeypox. Local COVID cases have been on a downward trajectory for more than a month. But a wastewater surveillance program led by UNLV Kirk Kerkorian School of Medicine professor and infectious disease expert Edwin Oh has started tracking monkeypox,making Southern Nevada among the first few metropolitan areas nationwide to begin searching the sewers for the emerging virus.
Infectious Disease Expert Available to Address Recent Polio Case and Increase in Monkeypox Cases
Sandra A. Kemmerly, MD, MACP, FIDSA joined the Ochsner staff in 1988 and is board certified in both internal medicine and infectious diseases. She maintains an active practice and is the clinical lead for Ochsner Healths Covid response in addition…
Dr. Baumgarten Available to Address Recent Polio Case and Increase in Monkeypox Cases
Dr. Baumgarten currently serves as Medical Director of Infection Control and Prevention for Ochsner Health since 2008, during which time she been involved in preventing transmissible diseases in the Ochsner System and our community. Over the past two years, she…
Disparities in United States COVID-19 Vaccine Distribution
Health care facilities in Black metropolitan counties, Hispanic rural counties and hardest-hit counties were less likely to administer COVID-19 vaccines during initial rollout, UC San Diego study finds.
Post-COVID Lung Disease Shares Origins with Other Scarring Lung Disorders
UC San Diego researchers provide first insights into the fundamental cellular pathologies that drive interstitial lung disease in patients post-COVID.
Mayo Clinic Laboratories launches monkeypox test to increase access, availability
Mayo Clinic Laboratories can now test for monkeypox, a rare viral infection, using the Centers for Disease Control and Prevention’s (CDC) orthopoxvirus test kit.
Awash in Potential: Wastewater Provides Early Detection of SARS-CoV-2 Virus
Scientists and physicians at UC San Diego and Scripps Research describe how wastewater sequencing provided dramatic new insights into levels and variants of SARS-CoV-2 on campus and in the broader community — a key step to public health interventions in advance of COVID-19 case surges.
Familiarity Breeds Exempt: Why Staph Vaccines Don’t Work in Humans
UC San Diego researchers say they may have found the reason why multiple human clinical trials of staphylococcus vaccines have failed: the bacteria knows us too well.
Columbia University & CDC Partner With Zambian Scientists to Prevent Pandemics
Columbia University’s Global Alliance for Preventing Pandemics announces an agreement with the University of Zambia’s School of Veterinary Medicine and the U.S. Center for Disease Control and Prevention to train Zambian public health professionals to better identify and contain pathogen outbreaks.
Targeting a human protein to squash SARS-CoV-2 and other viruses
In ACS Infectious Diseases, scientists now report that apratoxin S4, an anticancer drug candidate that targets a human protein, can interfere with the replication of many viruses, including SARS-CoV-2 and influenza A, offering a possible pan-viral therapy.
Wastewater Surveillance for COVID-19: It’s Complicated
Elena Naumova, professor at the Friedman School of Nutrition Science and Policy at Tufts University, explains wastewater surveillance and testing, the underlying process and the pros and cons of its use.
COVID-19 Rebound after Taking Paxlovid Likely Due to Insufficient Drug Exposure
COVID-19 rebound following Paxlovid treatment likely due to insufficient drug exposure, UC San Diego researchers find after showing rebound patient did not show drug resistance or impaired immunity.
Kawasaki Disease Rates Dropped During COVID-19 Pandemic
UC San Diego researchers report significant decrease in national cases of Kawasaki disease during COVID-19 pandemic; findings hint at origins of disease.
COVID-19 on the Brain: Neurological Symptoms Persist in Majority of Long-Haulers
A UC San Diego study describes the short- and long-term neurological symptoms of SARS-CoV-2 infection, and identifies a new group of COVID-19 long-haulers with advanced motor and cognitive symptoms.
What Do We Know – and Need to Know – About Monkeypox?
Q&A about monkeypox with Dr. Anne Rimoin, UCLA Fielding School of Public Health professor of epidemiology and the Gordon-Levin Endowed Chair in Infectious Diseases and Public Health, has been studying monkeypox for two decades.
Infectious disease doctor answers questions about the monkeypox virus
The growing concern of recent outbreaks of the rare monkeypox virus reported in the U.S. and abroad have health authorities monitoring transmission rates and keeping a close eye on the emerging issue. Charles Schleupner, a professor of internal medicine who…
The US reaches 1 Million Deaths from COVID-19: GW Experts Available to Comment
The United States has reached 1 million reported deaths from COVID-19 and that number is likely an undercount, according to the Centers for Disease Control and Prevention. The George Washington University has a number of experts to comment on the…
COVID-19, MIS-C and Kawasaki Disease Share Same Immune Response
COVID-19, MIS-C and KD all share a similar underlying mechanism involving the over-activation of particular inflammatory pathways, UC San Diego study shows. Findings support novel drug targets for MIS-C.
Dr. Anne Rimoin Named to new Gordon–Levin Chair in Infectious Diseases and Public Health at UCLA Fielding School of Public Health
Dr. Anne Rimoin, an internationally recognized expert on emerging infections, global health, infectious disease surveillance systems and vaccinations who has been engaged in pandemic preparedness and response work for more than two decades, has been appointed to the newly established Gordon–Levin Endowed Chair in Infectious Diseases and Public Health at the UCLA Fielding School of Public Health.
Virtual Village Treats HIV-associated Loneliness in Novel UC San Diego Health Trial
A new trial by UC San Diego Health infectious disease specialist Maile Young Karris, MD, will use longitudinal questionnaires and qualitative interviews to assess the impact of living in an interconnected virtual village on the loneliness known to afflict older people with HIV.
Hepatitis A Vaccination Required for Herd Immunity in People Experiencing Homelessness or Who Use Drugs
In the U.S., hepatitis A outbreaks are repeatedly affecting people experiencing homelessness or who use drugs. A 2017-19 Kentucky outbreak primarily among these groups resulted in 501 cases, six deaths. Vaccination efforts likely averted 30 hospitalizations and $490K in costs,…
Pregnant Women Who Receive COVID-19 Vaccination Pass Protection from the Virus to Their Newborns
Women who receive COVID-19 mRNA vaccines during pregnancy pass high levels of antibodies to their babies, a new NYU Langone study finds.
Hospital AI Learns to Say ‘I Don’t Know’
Sepsis occurs when the body works so hard to fight an infection that the immune system injures the patient’s own tissues. Detecting sepsis early and delivering antibiotics promptly is key to saving lives. UC San Diego Health researchers developed an…
Infection detection: DNA researchers develop critical shortcut to detect and identify known and emerging pathogens
Researchers at McMaster University have developed a sophisticated new tool that could help provide early warning of rare and unknown viruses in the environment and identify potentially deadly bacterial pathogens which cause sepsis, among other uses.
3D analysis of SARS-CoV-2 reveals clues on virus tactics
The most comprehensive analysis of the 3D structure of SARS-CoV-2 to date has revealed new insight on how the virus infects human cells and replicates.
Study: No Serious COVID-19 Vaccine Side Effects in Breastfeeding Moms, Infants
Researchers found that breastfeeding mothers who received either the Pfizer-BioNTech or Moderna vaccination reported the same local or systemic symptoms as what has been previously reported in non-breastfeeding women, with no serious side effects in the breastfed infants.
Valley Fever more common in Utah than previously thought, researchers find
A new research study reveals that Valley Fever, a fungal disease most commonly found in Arizona and California, may be more common in Utah than previously thought.
With Time and Without Masks, COVID-19 Vaccines Wane in Protection
A study measured effectiveness of COVID-19 mRNA vaccines among health workers, most notably during the emergence of delta virus variant and coincident with end of state’s mask mandate, finding protection waned over time, dropping sharply 6-8 months after full vaccination.
2VIDA! Tackles COVID Vaccine Hesitancy and Barriers in Latinx, Black Communities
UC San Diego is collaborating with San Ysidro Health on an NIH-funded outreach program to address COVID-19 vaccine hesitancy in Latinx and African American communities. The team runs pop-up vaccination sites across San Diego, and goes door-to-door to homes and local businesses to spread awareness.
Symptomatic COVID patients are more contagious
Individuals with COVID-19 are most likely to spread the virus to close contacts two days before the onset of symptoms to three days after symptoms appear, and the risk of transmission is highest when patients had mild or moderate disease severity, according to a new study by researchers at the University of Georgia.
COVID-19 is most transmissible 2 days before and 3 days after symptoms appear
Each wave of the pandemic has underscored just how gravely contagious COVID-19 is, but there is less clarity among experts on exactly when—and to what extent—infected individuals are most likely to spread the virus.
Most of UC San Diego’s COVID-19 Cases Detected Early by Wastewater Screening
Part of UC San Diego’s Return to Learn program, wastewater screening helped prevent outbreaks by detecting 85 percent of cases early, allowing for timely testing, contact tracing and isolation.
Young, Healthy Woman Suffers Brain Inflammation after Mild COVID-19 Infection
UC San Diego Health physicians describe first known case of young, healthy adult experiencing central nervous system inflammation due to COVID-19, but without cognitive impairment.
Licensed Drug Could Reduce SARS-CoV-2 Infection by Up to 70 Per Cent, Reveals Study
A licensed drug normally used to treat abnormal levels of fatty substances in the blood could reduce infection caused by the SARS-CoV-2 virus by up to 70 per cent, reveals a study in the laboratory by an international collaboration of researchers.
Organ Transplant Recipients Significantly Protected by COVID-19 Vaccination
UC San Diego researchers report that solid organ transplant recipients who were vaccinated experienced an almost 80 percent reduction in the incidence of symptomatic COVID-19 compared to unvaccinated counterparts during the same time.
The Future of Masking Post-Vaccination
The COVID-19 vaccine is your best defense against the virus, but when and where should you continue to wear a mask? Rush infectious disease expert Michael Lin, MD, answers questions about wearing a mask post-vaccination.
Rethinking Remdesivir
UC San Diego researchers modify remdesivir, creating oral version that can be taken earlier in COVID-19 diagnoses. In cell and animal studies, revised drug proved effective and safe.
New Insights Into Immune Responses to Malaria
Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically.
3D “Assembloid” Shows How SARS-CoV-2 Infects Brain Cells
Researchers at UC San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine have produced a stem cell model that demonstrates a potential route of entry of SARS-CoV-2, the virus that causes COVID-19, into the human brain.
Common Medication Used to Reduce Cholesterol Levels May Reduce COVID-19 Severity
Using anonymized medical records from a national registry, UC San Diego researchers confirm earlier findings that statins may substantially minimize adverse outcomes from SARS-CoV-2 infection.
Only 20 states implemented health equity committees to assist with COVID-19 vaccine distribution planning
A new study out of UChicago found that while 43 states (out of 51, including all 50 states and Washington, D.C.) created a committee to develop a vaccine distribution plan, only 20 plans mentioned using a health equity committee to assist with plan development.
Vaccines grown in eggs induce antibody response against an egg-associated glycan
Researchers have found that viral vaccines grown in eggs, such as the H1N1 flu vaccine, produce an antibody response against a sugar molecule found in eggs, which could have implications for the effectiveness of these vaccines.
Prevalence of COVID-19 Among Hospitalized Infants Varies with Levels of Community Transmission
How common COVID-19 is among infants may depend on the degree of the pandemic virus circulating in a community, a new study finds.
UC San Diego Health Adopts SMART Health Card for Digital Vaccine Records
UC San Diego Health is now offering a verifiable digital vaccine record to its patients who have or will receive a COVID-19 vaccine. These secure online records, otherwise known as a SMART health card, can be accessed directly from the MyUCSDChart patient portal.
Counties with state prisons had 11% more first-wave COVID-19 cases
MADISON – The presence of a state prison in a county was associated with 11% more COVID-19 cases through July 1, 2020, according to a new study from the University of Wisconsin–Madison.