Fight CRC To Present Research Findings on The Impact of COVID-19 on the Colorectal Cancer Community at 2021 GI ASCO

Fight Colorectal Cancer presents abstract at Gastrointestinal Cancer Symposium highlighting the need to address the barriers and opportunities for care within the colorectal cancer community during the COVID-19 pandemic

Mount Sinai Finds That Transgender Women Can Safely Stay On Their Hormone Treatments During Gender Affirming Surgery, Without An Increase of Blood Clots

This is the first study to demonstrate that there is no difference in blood clots when transgender women remain on estrogen hormone therapy for gender affirming surgery. Because both estrogen therapy and surgery can increase a person’s risk of blood clots, experts had long suggested that transgender women stop taking estrogen when undergoing gender affirming surgery. However, there was previously no published data on the blood clot risk specific to transgender women undergoing surgery.

CHOP Researchers Find NTRK Fusions More Common than Expected in Pediatric Tumors

In a large study of pediatric cancer patients, researchers from Children’s Hospital of Philadelphia (CHOP) have analyzed the frequency, fusion partners, and clinical outcome of neurotrophic tyrosine receptor kinase (NTRK) fusions, which are clinical biomarkers that identify patients suitable for treatment with FDA-approved TRK inhibitors. The researchers found that NTRK fusions are more common in pediatric tumors and also involve a wider range of tumors than adult cancers, information that could help prioritize screening for NTRK fusions in pediatric cancer patients who might benefit from treatment with TRK inhibitors.

Accounting for the gaps in ancient food webs

Studying ancient food webs can help scientists reconstruct communities of species, many long extinct, and even use those insights to figure out how modern-day communities might change in the future. There’s just one problem: only some species left enough of a trace for scientists to find eons later, leaving large gaps in the fossil record — and researchers’ ability to piece together the food webs from the past.

A new paper shines a light on those gaps and points the way to how to account for them.

Acute itching in eczema patients linked to environmental allergens

New research from Washington University School of Medicine in St. Louis indicates that allergens in the environment often are to blame for episodes of acute itch in eczema patients, and that the itching often doesn’t respond to antihistamines because the itch signals are being carried to the brain along a previously unrecognized pathway that current drugs don’t target.

UNH Researchers Discover New Inhibitor Drug Combination for Rare Form of Cancer

Waldenström macroglobulinemia (WM), a rare form of lymphoma, does not have any known cure and only one FDA-approved treatment making it challenging to treat patients. Researchers at the University of New Hampshire took the novel approach of targeting specific cell proteins that control DNA information using inhibitors, or drugs, that were effective in reducing the growth of the cancer cells and when combined with a third drug were even more successful in killing the WM cancer cells which could lead to more treatment options.

Astronomers document the rise and fall of a rarely observed stellar dance

Astronomers have catalogued 126 years of changes to HS Hydra, a rare evolving eclipsing binary. The two stars in HS Hydra began to eclipse each other starting around a century ago, peaking in the 1960s. The degree of eclipsing then plummeted over the course of just a half century, and will cease around Feb. 2021.

University of Chicago undergrads discover bright lensed galaxy in the early universe, despite pandemic barriers

A class of undergraduate astrophysics students at the University of Chicago helped discover a galaxy that dates back to a time when the universe was only 1.2 billion years old, about one-tenth of its current age.

Girls Who Are Emotionally Neglected or Severely Sexually Abused When Young Report Riskier Sexual Behaviors in Adolescence

Girls who are emotionally neglected or severely sexually abused early in their lives report riskier sexual behaviors during adolescence, Mount Sinai researchers report. The findings highlight the need—and suggest the potential for tailored approaches—to promote healthy sexual development in vulnerable populations.

Borrowing from birds, experts reduce search times for novel high-entropy alloys to seconds

Computational materials science experts at the U.S. Department of Energy’s Ames Laboratory enhanced an algorithm that borrows its approach from the nesting habits of cuckoo birds, reducing the search time for new high-tech alloys from weeks to mere seconds.

MIND and Mediterranean diets associated with later onset of Parkinson’s disease

A new study from UBC researchers suggests a strong correlation between following the MIND and Mediterranean diets and later onset of Parkinson’s disease (PD). While researchers have long known of neuroprotective effects of the MIND diet for diseases like Alzheimer’s and dementia, this study is the first to suggest a link between this diet and brain health for Parkinson’s disease (PD).

Population density and virus strains will affect how regions can resume normal life

As a new, apparently more transmissible version of the virus that causes COVID-19 has appeared in several countries, new research finds that the transmissibility of viral strains and the population density of a region will play big roles in how vaccination campaigns can help towns and cities return to more normal activities. The findings suggest that directing vaccines toward densely populated counties would help to interrupt transmission of the disease.

Neither ‘meniscal’ nor ‘mechanical’ symptoms predict findings on knee arthroscopy

Orthopaedic surgeons have traditionally been taught that certain types of knee symptoms indicate damage to specialized structures called the menisci. But these “meniscal” and “mechanical” symptoms do not reflect what surgeons will find at knee arthroscopy, reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

Study shows sharp decline in cancer screenings and diagnoses during the first COVID-19 surge

In one of the first studies to examine the impact of the COVID-19 pandemic on cancer diagnoses, researchers at Dana-Farber/Brigham and Women’s Cancer Center document a substantial decline in cancer and precancer diagnoses at the Northeast’s largest health care system during the first peak of the pandemic because of a drop in the number of cancer screening tests performed.

Scientists Take Important Step Toward Using Retinal Cell Transplants to Treat Blindness

Retinal cells derived from a cadaver human eye survived when transplanted into the eyes of primate models, an important advance in the development of cell therapy to treat blindness, according to a study published on January 14 in Stem Cell Reports.

The Richer You are, The More Likely You’ll Social Distance, Study Finds

The higher a person’s income, the more likely they were to protect themselves at the early stages of the Covid-19 pandemic in the United States, Johns Hopkins University economists find.

When it comes to adopting behaviors including social distancing and mask wearing, the team detected a striking link to their financial well-being. People who made around $230,000 a year were as much as 54% more likely to increase these types of self-protective behaviors compared to people making about $13,000.

Behaviors Surrounding Oral Sex May Increase HPV-Related Cancer Risk

A wide breadth of behaviors surrounding oral sex may affect the risk of oral HPV infection and of a virus-associated head and neck cancer that can be spread through this route, a new study led by researchers at the Johns Hopkins Kimmel Cancer Center suggests. These findings add nuance to the connection between oral sex and oropharyngeal cancer — tumors that occur in the mouth and throat — and could help inform research and public health efforts aimed at preventing this disease.