Are Too Many Phase III Cancer Clinical Trials Set Up to Fail?

New research in JNCCN finds four out of five cancer therapies tested in Phase III trials do not achieve clinically-meaningful benefit in prolonging survival, and is the first study to quantify the number of false-positive, false-negative, and true-negative trial results.

FAU Receives NSF Grant to Explore Trait Evolution Across Species

The NSF grant will enable scientists to elucidate trait evolution across species using statistical and supervised machine learning approaches to vigorously and accurately predict general and specific evolutionary mechanisms that also will be applicable to various genomic and transcriptomic data for evolutionary discovery.

U.S. Researchers Simulate Compact Fusion Power Plant Concept

The Compact Advanced Tokamak (CAT) concept uses physics models to show that by carefully shaping the plasma and the distribution of current in the plasma, fusion plant operators can suppress turbulent eddies in the plasma. This would reduce heat loss and allow more efficient reactor operation. This advance could help achieve self-sustaining plasma and smaller, less expensive power plants.

Campaigning for More Marie Curies: More Women Means Changes for Physics, Engineering

Amy Sue Bix, a leading expert on the history of science and women and gender studies, will speak in an upcoming Lyne Starling Trimble lecture Wednesday, Sept. 29, in a live webcast. Her talk will delve into how the dramatic shift of girls and young women toward STEM occurred, how diversity will play a role in the nature and purpose of science and engineering, the changes in gender relations in the scientific community, and escalating concern for girls’ psychological well-being and personal opportunities.

Rutgers Cancer Institute Research: Abdominal Fat Linked to Worse Outcomes for Black Breast Cancer Survivors

Findings from a recent population based cohort study published online in JAMA Oncology show that Black women diagnosed with breast cancer who also have central obesity, which means excess body fat in the abdominal area, were more likely to die from breast cancer or any other cause than similar women who didn’t have central obesity.

10 questions you want answered on COVID-19

Should children under the age of 12 be vaccinated against COVID-19? Is it possible to achieve herd immunity? Will an 80 per cent vaccination rate keep us safe? In this video, UniSA epidemiologist Professor Adrian Esterman answers these questions and a lot more. The former World Health Organization consultant shares his expertise – 50 years’ worth – and argues for a different approach to tackling COVID-19.
https://www.youtube.com/watch?v=MLKC9q9yEto

Sanford Burnham Prebys professor Karen Ocorr awarded $2 million from NASA to study flies in space

As part of their larger initiative to understand the effects of space conditions on different organisms, NASA has awarded $2 million to Sanford Burnham Prebys assistant professor Karen Ocorr. The grant will fund a three-year project to study the effects of low gravity on muscle and neuron function in fruit flies and nematode worms aboard the International Space Station.

Could a Novel Light Therapy Help People With Alzheimers?

Recently, the National Institutes of Health (NIH) awarded researchers at the Icahn School of Medicine at Mount Sinai a five-year grant to out whether exposing patients to a combination of light therapies will slow Alzheimer’s debilitating effects.

Researchers Define Chain of Events Leading to Dangerous Intestinal Disorder in Preemies

In a study with mice reported today in the journal Science Translational Medicine, a Johns Hopkins Medicine research team has provided what may be the most definitive view to date of the biological process leading to necrotizing enterocolitis (NEC), a dangerous inflammatory disease that can destroy a premature infant’s intestinal lining and causes death in up to a third of the cases.

Three Advances in Breast Cancer Treatment are Saving More Lives

The outlook for patients diagnosed with breast cancer has been changing for the better over time thanks to surgical advances, clinical trials & a more personalized treatment approach. Dr. Lindsay Potdevin, surgical oncologist at Rutgers Cancer Institute of New Jersey, shares how these advances are improving the lives of patients.

How Do Migraines Affect the Sleep Cycle?

Adults and children with migraines may get less quality, REM sleep time than people who don’t have migraines. That’s according to a meta-analysis published in the September 22, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. Children with migraines were also found to get less total sleep time than their healthy peers but took less time to fall asleep.

Adults with Neurologic Conditions More Likely to Have Experienced Childhood Trauma

Adults with neurologic conditions are more likely than the general population to have had adverse childhood experiences such as abuse, neglect or household dysfunction, according to a study published in the September 22, 2021, online issue of Neurology® Clinical Practice, an official journal of the American Academy of Neurology.

Master of Business Creation startup founders for 2021-22

The Department of Entrepreneurship & Strategy at the University of Utah’s David Eccles School of Business welcomed the third class of founders in the Master of Business Creation (MBC) program this fall semester for the 2021-22 academic year. The program is offered with support from the Lassonde Entrepreneur Institute. The group consists of 23 founders who have launched 18 companies with products and services ranging from choke-prevention devices and delivery logistics to party planning and luxury pajamas. All have already made progress in starting their companies and are looking to grow sales and attract investors, among other goals.

Hackensack Meridian Hackensack University Medical Center Recognized as 2021 Age-Friendly Health System – Committed to Care Excellence

Hackensack Meridian Hackensack University Medical Center was recently recognized by Age-Friendly Health Systems, an initiative of The John A. Hartford Foundation and the Institute for Healthcare Improvement (IHI), in partnership with the American Hospital Association (AHA) and the Catholic Health Association of the United States (CHA), Hackensack Meridian Hackensack University Medical Center is among the health systems in the country implementing age-friendly health care.

Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients

Original Investigation September 21, 2021 Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients A Randomized Clinical Trial   Author Affiliations Article Information JAMA. 2021;326(11):1024-1033. doi:10.1001/jama.2021.13355   visual abstract icon  Visual Abstract Key Points Question  Does the probiotic Lactobacillus rhamnosus GG prevent ventilator-associated pneumonia (VAP)…

UA Little Rock Math Professor Selected as Inaugural Recipient of Top Hat Black Educator Grant

A University of Arkansas at Little Rock math educator has been selected as one of the inaugural recipients of Top Hat’s Black Educator Grant. Dr. Lakeshia Legette Jones, an associate professor of mathematics and statistics, will receive a $10,000 grant, as well as free access to Top Hat’s active learning courseware platform for her students.