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UrduDigital ILC 2020: The liver community has been prompt in addressing the challenges of COVID-19 for liver patients – joining forces to support these patients, provide recommendations to their doctors, and keep research at the forefront.
Tag: Gastroenterology
Liver fibrosis in routine care for diabetes could uncover advanced liver disease patients
Digital ILC 2020: A pilot study from the UK has suggested that diagnosis of advanced liver disease in people living with diabetes could be increased 5-fold if the assessment of liver fibrosis is included in routine care.
Immune protein IL-17A responsible for lethal side effects of gastric cancer
Researchers from Kanazawa University find that as gastric cancer spreads throughout the peritoneal cavity, inflammatory protein IL-17A induces tissue fibrosis, causing lethal side effects and hampering chemotherapy.
Gastrointestinal innovation holds potential for treating variety of conditions
Newly developed synthetic lining could deliver drugs in a sustained way to the small intestine
Synthetic coating for the GI tract could deliver drugs or aid in digestion
MIT engineers devise a temporary film that may help treat diabetes, infections, and other conditions
Changes in gut microbiota can greatly impact alcohol-related liver disease and cancer risk
Digital ILC 2020: Studies evaluating fecal microbial transplant and inflammatory signalling highlight the significance of gut microflora in alcohol-related liver disease and hepatocarcinogenesis
New models help predict liver cancer after successful hepatitis C virus (HCV) treatment
Digital ILC 2020: European scientists develop new predictive models for HCC in patients with chronic HCV after a sustained virological response to direct-acting antiviral therapy
Prioritizing patients using MELD-Na reduces liver transplant waiting-list mortality
Digital ILC 2020: European study reports that prioritizing patients for liver transplantation using MELD-Na could reduce 90-day waiting-list mortality compared with current practice
Two novel treatments show promise in improving biomarkers of NASH pathology
Digital ILC 2020: As new data highlight the increasing prevalence of NAFLD, two new treatments have demonstrated reductions in ALT, hepatic fat and other indicators of liver disease, including in patients with type 2 diabetes
Magnetic stimulation dramatically improves fecal incontinence
Painless magnetic stimulation of nerves that regulate muscles in the anus and rectum appears to improve their function and dramatically reduce episodes of fecal incontinence, a debilitating problem affecting about 10% of the population, investigators report. They have early evidence…
Inflammatory Bowel Disease Linked to an Immune Cell Run Amok
Researchers at UC San Diego School of Medicine report that the lasting nature of inflammatory bowel disease may be due to a type of long-lived immune cell that can provoke persistent, damaging inflammation in the intestinal tract.
Excessive Fructose Consumption May Cause a Leaky Gut, Leading to Fatty Liver Disease
Researchers at University of California San Diego School of Medicine report that fructose only adversely affects the liver after it reaches the intestines, where the sugar disrupts the epithelial barrier protecting internal organs from bacterial toxins in the gut.
Global gut health experts guide growth of synbiotics
URBANA, Ill. – Chances are you’ve heard of or even taken probiotics: supplements delivering “good microbes” to the gut, providing a wide range of health benefits. If you’re really up on your gut health, you may also be aware of…
Molecule secreted by cancer-associated fibroblasts promotes anticancer drug resistance
A joint project led by Kumamoto University (Japan) has discovered a new mechanism for anticancer drug resistance in gastric cancer. Researchers found that the Annexin A6 molecule contained in extracellular vesicles (EVs) is secreted by cancer-associated fibroblasts (CAFs) and taken…
Studies of gut microbiota and contractility help deal with chronic constipation
A paper by Kazan Federal University and Kazan State Medical University appeared in PLOS ONE.
Inventing new tools to peer into the gastrointestinal tract
New sensors can reveal therapeutic targets, impact of probiotics
Researchers identify enzyme linked to colitis
Rutgers-Newark study may help develop future treatments for inflammatory bowel disease
Antibiotics associated with increased risk of inflammatory bowel disease
Antibiotics use, particularly antibiotics with greater spectrum of microbial coverage, may be associated with an increased risk of new-onset inflammatory bowel disease (IBD) and its subtypes ulcerative colitis and Crohn’s disease. That is according to a study by researchers at…
Diabetes, weight change and pancreatic cancer risk
What The Study Did: Researchers investigated an association between the duration of diabetes and recent weight loss with subsequent risk of pancreatic cancer in this observational study. Authors: Chen Yuan, Sc.D., of the Dana-Farber Cancer Institute and Harvard Medical School…
New microrobot with in situ, in vivo bioprinting offers promise for gastric wounds
Researchers in China have taken the first step towards a new way of treating gastric wounds by using a microrobot combined with the new concept of “in situ in vivo bioprinting” to carry out tissue repair inside the body. Their…
Enzyme discovered in the gut could lead to new disease biomarker
Enzymes used by bacteria to break down mucus in the gut could provide a useful biomarker for intestinal diseases, according to new research published in Nature Communications . Researchers at the University of Birmingham and Newcastle University have successfully identified…
Gluten in wheat: What has changed during 120 years of breeding?
Modern wheat is off the hook?
Gut microbes shape our antibodies before we are infected by pathogens
B cells are white blood cells that develop to produce antibodies.
Scientists discover novel drug target for pancreatic cancer
Scientists at Sanford Burnham Prebys Medical Discovery Institute have uncovered a novel drug target, a protein called PPP1R1B, that stops the deadly spread of pancreatic cancer, called metastasis, when inhibited in mice. Published in Gastroenterology, the findings are a first step toward a potential treatment for one of the deadliest cancers known today.
Tool could improve success in translating drugs from animal studies to humans
WEST LAFAYETTE, Ind. — About 50% of people who take the drug infliximab for inflammatory bowel diseases, such as Crohn’s disease, end up becoming resistant or unresponsive to it. Scientists might be able to catch problems like this one earlier…
Baylor Scott & White Health Again Recognized as Most Awarded Not-for-profit Health System in Texas by U.S. News & World Report
In the midst of the extraordinary health challenge presented by the COVID-19 pandemic, Baylor Scott & White Health remains committed to quality, safe care and helping Texas communities navigate the uncertainty of the SARS-CoV-2 virus. Today, this commitment to safety and quality is recognized as U.S. News & World Report releases its 2020-2021 Best Hospitals list.
UC San Diego Health Ranked #1 by U.S. News & World Report
UC San Diego Health is ranked first in San Diego and sixth in California, placing it among the nation’s best hospitals, according to the 2020-2021 U.S. News & World Report. Eight common procedures and conditions were also rated “high performing.”
The Mount Sinai Hospital Ranked Among Top in the Nation by U.S. News & World Report; Brookdale Department of Geriatrics and Palliative Medicine Claims No. 1 Spot in Specialty Rankings
The Mount Sinai Hospital, the flagship hospital of Mount Sinai Health System, was listed among the nation’s top hospitals for care excellence in U.S. News and World Report, marking the fifth straight year the hospital has been listed among the top 20 in the country while landing on the distinctive “Honor Roll” list.
Closing the gap: finding undiagnosed hepatitis C infections after blood transfusions
Results from a retrospective cohort study looks at transfusions before and after Sweden introduced screening of blood in the early 1990s
Mix and match: New 3D cell culture model replicates fibrotic elements of pancreatic cancer
Researchers use 3D cell culture technology to recreate pancreatic cancer tissue in vitro with fibrotic components
Antioxidant-rich powders from blueberry, persimmon waste could be good for gut microbiota
Feeding the world’s growing population in a sustainable way is no easy task. That’s why scientists are exploring options for transforming fruit and vegetable byproducts — such as peels or pulp discarded during processing — into nutritious food ingredients and…
How viruses and bacteria balance each other in the gut microbiome
A tiny arms race playing out inside the gut could eventually offer a new way to treat out-of-balance microbiomes
How viruses and bacteria balance each other in the gut microbiome
A tiny arms race playing out inside the gut could eventually offer a new way to treat out-of-balance microbiomes
How to repair your gut
In a world first, Monash University researchers have identified a key biomolecule that enhances the repair of your gut lining by prompting stem cells to regenerate damaged tissue. A strong cellular lining is essential for a healthy gut as it…
Juanita L. Merchant Appointed to the Ludwig Institute’s Scientific Advisory Committee
Ludwig Cancer Research welcomes Juanita L. Merchant to the Scientific Advisory Committee of the Ludwig Institute for Cancer Research.
Gut microbiota provide clues for treating diabetes
The individual mix of microorganisms in the human gastrointestinal tract provides vital clues as to how any future incidence of type 2 diabetes can be predicted, prevented and treated.
Increased Risk of COVID-19 Among Users of Proton Pump Inhibitors (PPIs)
Findings from an online survey of more than 53,000 American adults suggest that using heartburn medications known as proton pump inhibitors (PPIs) once or twice daily significantly increases the odds of a positive test for COVID-19 compared to those who do not take PPIs. This research appeared online July 7, 2020 in pre-print format in The American Journal of Gastroenterology.
Rapid genomic profiling of colon cancers can improve therapy selection for patients
Multicenter study led by Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center shows vastly improved turnaround time to get results from the lab to the oncologist using the newest technology in the cancer testing space.
Examining association between older age, risk of complications after colonoscopy
What The Study Did: This observational study looked at the risk of complications after an outpatient colonoscopy among patients age 75 and older compared to younger patients. Authors: David Armstrong, M.D., of McMaster University in Hamilton, Ontario, Canada, is the…
Examining association between older age, risk of complications after colonoscopy
What The Study Did: This observational study looked at the risk of complications after an outpatient colonoscopy among patients age 75 and older compared to younger patients. Authors: David Armstrong, M.D., of McMaster University in Hamilton, Ontario, Canada, is the…
Could the cure for IBD be inside your mouth?
A new study describes how poor oral health may worsen gut inflammation
Could the cure for IBD be inside your mouth?
A new study describes how poor oral health may worsen gut inflammation
Researchers uncover drivers of healthy gut maintenance
Researchers at the Francis Crick Institute have found two genes that regulate the differentiation of stem cells in the small intestine, offering valuable insight into how the body develops and maintains a healthy gut. Cells in the lining of the…
Researchers uncover drivers of healthy gut maintenance
Researchers at the Francis Crick Institute have found two genes that regulate the differentiation of stem cells in the small intestine, offering valuable insight into how the body develops and maintains a healthy gut. Cells in the lining of the…
International NASH Day declares urgency to combat epidemics of liver disease and COVID
Obesity, type II diabetes, and high blood pressure increase the risk of NASH and negatively affect outcomes for COVID-19 patients
Royal Marsden trial leads to practice changing milestone for advanced anal cancer
Results from the first ever randomised clinical trial in advanced anal cancer patients, led and supported by The Royal Marsden NHS Foundation Trust and Cancer Research UK, in collaboration with colleagues in the US, Norway and Australia, has led to…
Prevalence of gastrointestinal symptoms, fecal viral shedding in patients with COVID-19
What The Study Did: How commonly reported gastrointestinal symptoms were in patients with COVID-19 and viral RNA shedding was detected in these patients’ stool are examined in this systematic review and meta-analysis. Authors: Sravanthi Parasa, M.D., of Swedish Medical Center…
Prevalence of gastrointestinal symptoms, fecal viral shedding in patients with COVID-19
What The Study Did: How commonly reported gastrointestinal symptoms were in patients with COVID-19 and viral RNA shedding was detected in these patients’ stool are examined in this systematic review and meta-analysis. Authors: Sravanthi Parasa, M.D., of Swedish Medical Center…
Happiness Might Protect You From Gastrointestinal Distress
DALLAS – June 9, 2020 – Serotonin, a chemical known for its role in producing feelings of well-being and happiness in the brain, can reduce the ability of some intestinal pathogens to cause deadly infections, new research by UT Southwestern scientists suggests. The findings, publishing online today in Cell Host & Microbe, could offer a new way to fight infections for which few truly effective treatments currently exist.
AGA does not recommend the use of probiotics for most digestive conditions
New AGA guideline finds that evidence to support use of probiotics to treat digestive diseases is greatly lacking, identifying only three clinical scenarios where probiotics may benefit patients