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UrduUCSF researchers systematically tested CSF1R inhibition using multiple drug analogs at several time points in transgenic mice developing spontaneous tauopathy. The researchers demonstrated a reduction of tau pathology in multiple dosing schemes without complete microglial ablation.
Month: January 2023
UVA Darden Partners with Billie Jean King Leadership Initiative on New Case Series
The University of Virginia Darden School of Business Institute for Business in Society has partnered with the Billie Jean King Leadership Initiative to produce a series of case studies on topics including women in leadership, inclusion, access and opportunity.
Chula Medicine Reveals Innovative Detection of Latent Dementia A 10-Year Awareness May delay Alzheimer’s Onset in Elderly
Thai Red Cross Emerging Infectious Diseases Health Science Center, Faculty of Medicine, Chulalongkorn University has researched a blood test for markers of Alzheimer’s that can give a 10-year warning, so people can be prepared to slow down the development of dementia in old age.
Center for Bioenergy Innovation adds three new board members
The Department of Energy’s Center for Bioenergy Innovation, led by Oak Ridge National Laboratory, recently added three new members to its board of directors: Deborah Crawford of the University of Tennessee, Knoxville; Susan Hubbard of ORNL; and Maureen McCann of the National Renewable Energy Laboratory.
Learn CPR and Lower Your Stress: Mount Sinai Cardiologists Emphasize Their Importance During American Heart Month
Doctors warn about lack of knowledge of administering CPR, especially in high-risk groups, and the rise of stress-related heart issues
University of Pennsylvania’s Perelman School of Medicine Announces Withdrawal from Participation in U.S. News & World Report’s “Best Medical Schools” Rankings
The University of Pennsylvania’s Perelman School of Medicine (PSOM) today announced that it will no longer submit data for participation in the U.S. News and World Report (USNWR) annual “Best Medical Schools” rankings.
Want More Than Romance This Valentine’s Day? Halt Spring Allergy Symptoms Before They Start
Spring allergy symptoms will start to appear soon in parts of the country. Many allergists advise their patients to set a reminder for Valentine’s Day to start taking allergy medications.
UT Southwestern ophthalmologist shares techniques for cataract surgery complications
Patients undergoing cataract surgery typically have their natural lens replaced with an artificial intraocular lens (IOL). But complications occasionally arise that require the placement of a more surgically challenging secondary IOL. Several techniques are available for secondary IOL placement, and each has its advantages and disadvantages.
AANS/CNS Cerebrovascular Section and American Society of Stereotactic and Functional Neurosurgery Contribute to SNS Neurosurgeon-Scientist Training Program
The Cerebrovascular Section of the American Association of Neurological Surgeons and Congress of Neurological Surgeons and the American Society for Stereotactic and Functional Neurosurgery joined in supporting the Society of Neurological Surgeons newly launched Neurosurgeon-Scientist Training Program.
Supporting evidence-based policymaking in The Gambia
A new IIASA policy brief outlines the recommendations, tools, and key findings of the FACE-Africa project, co-developed with Gambian food system stakeholders to help the country adapt to climate change and ensure sufficient healthy food for its people.
Identity, not income, drives desire to secede
What most sparks a region’s desire to seek independence from their country – income or identity? A new study from SMU (Southern Methodist University, Dallas) and UC3M (Universidad Carlos III de Madrid, Spain) found that the group people identify with tends to play a bigger factor in secession than differences in per capita income between regions.
Coating bubbles with protein results in a highly stable contrast agent for medical use
Bacteria produce gas vesicles, tiny thin-walled sacs filled with air or fluid, to help them float. This captured the attention of researchers at Aalto University’s Department of Applied Physics, who saw the potential for similar bubble-based designs in fields like…
A design of experiments approach to precision vaccine adjuvants
Adjuvants are added to vaccines to improve protection, extend the duration of protection and reduce the dose or number of boosters required.
F1 driver seat ‘avatar’ has potential to improve comfort and performance
Formula 1 team Williams Racing has partnered with University experts to develop the first-known driver seat using pioneering biomechanics technology
Online Tool Can Help Researchers Synthesize Millions of Molecules
New improvements to an open-source platform streamline enzyme engineering.
What Does the Debt-Ceiling Fight Mean to You?
Hitting the debt ceiling – how much money the federal government can borrow to pay its bills – could lead to economic catastrophe if the situation isn’t handled appropriately, said John Longo, a professor of professional practice at Rutgers Business…
Neuroscience reveals complexity of human brain networks
Scientists detected simple movement like pushing a button sends ripples of activity throughout networks of neurons spanning across the brain.
UTEP to Build on Research Strengths with Brookhaven National Laboratory Partnership
The University of Texas at El Paso signed a memorandum of understanding with the U.S. Department of Energy’s Brookhaven National Laboratory to create new research opportunities for UTEP faculty and students as well as internship and employment opportunities in critical fields such as energy, data science and quantum information.
Coordination of COVID-19 Vaccine Clinical Trials Produces a ‘Treasure Trove’ of Data and a Model for the Future
The federally funded COVID-19 Prevention Network was instrumental in the rapid development of safe, effective and lifesaving COVID-19 vaccines during earlier phases of the pandemic. This vital work to expedite Phase 3 clinical trials also resulted in a ‘treasure trove’ of data, thanks to a highly collaborative and harmonized approach that can serve as a national and even international model for major research initiatives while also guiding responses to future public health emergencies.
Both high- and low-intensity exercise therapy beneficial for knee osteoarthritis
A randomized controlled trial comparing high- and low-dose exercise therapy for patients with knee osteoarthritis found that both types of exercise therapy produced similar outcomes in pain, function, and quality of life. High-dose therapy provided superior outcomes related to function in sports and recreation in the short term, with results subsiding after 6 months. The findings are published in Annals of Internal Medicine.
American College of Physicians recommends cognitive behavioral therapy or second-generation antidepressants for adults with major depressive disorder
The American College of Physicians (ACP) has issued an update of its guideline with clinical recommendations for nonpharmacologic and pharmacologic treatments of adults in the acute phase of major depressive disorder (MDD). In the updated clinical guideline, ACP recommends the use of either cognitive behavioral therapy (CBT) or second-generation antidepressants (SGAs) as initial treatment in adults with moderate to severe MDD, and suggests the combination of both, as an alternate initial treatment option. The guideline and supporting evidence reviews are published in Annals of Internal Medicine.
Study Comparing Early Interventions for Sepsis Shows Patients Have Identical Outcomes
Sepsis can cause dangerously low blood pressure, which is typically treated with intravenous (IV) fluids and/or a vasopressor, a drug that causes constriction of the blood vessels. Whether treatment of sepsis-induced low pressure should primarily be treated with IV fluids or vasopressors has been debated for decades with no clear answer.
Host-Cell Factors Involved in COVID-19 Infections May Augur Improved Treatments
Researchers at University of California San Diego and UC Riverside have further elucidated the molecular pathway used by the SARS-CoV-2 virus to infect human lung cells, identifying a key host-cell player that may prove a new and enduring therapeutic target for treating COVID-19.
Can Elephants Save the Planet?
In findings published in Proceedings of the National Academy of Sciences (PNAS), Saint Louis University researchers and colleagues report that elephants play a key role in creating forests which store more atmospheric carbon and maintaining the biodiversity of forests in Africa. If the already critically endangered elephants become extinct, rainforest of central and west Africa, the second largest rainforest on earth, would gradually lose between six and nine percent of their ability to capture atmospheric carbon, amplifying planetary warming.
Reduced krill lead to fewer pregnancies in humpback whales
New collaborative research shows reduced krill supplies lead to fewer pregnancies in humpback whales—a finding that could have major implications for industrial krill fishing.
Covid-19 in pregnant women can damage the placenta and the fetus
Using prenatal magnetic resonance imaging, a group of MedUni Vienna researchers examined the placentas and foetuses of women who tested positive for SARS-CoV-2 during pregnancy.
Virus plus microplastics equal double whammy for fish health
Microplastics—tiny particles generated as plastics weather and fragment—pose a growing threat to ecosystem and human health. A new laboratory study shows these threats extend beyond direct physical or chemical impacts, revealing that the presence of microplastics increases the severity of an important viral fish disease.
A low-cost sensor that detects heavy metals in sweat
The flexible copper sensor is made from ordinary materials: conductive copper adhesive tape, sheet of transparency film, paper label, nail varnish, circuit fabrication solution, and acetone.
Children learn to read faster – given appropriate challenges
Reading is the basis for most subjects, but a lot of children struggle to master it. Every fourth Norwegian boy aged 15 does not understand a complicated text. Girls do better.
Study reveals new genetic disorder that causes susceptibility to opportunistic infections
An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia. The discovery, reported Jan. 20 in the journal Science Immunology, will help identify people who carry this in-born error of immunity (IEI).
New enzyme could mean better drugs
Just as a choreographer’s notation tells a dancer to strike a particular pose, an enzyme newly discovered by Rice University scientists is able to tell specific molecules precisely how to arrange themselves, down to the angle of single hydrogen bonds.
Dietary nitrate – Increasing muscle force during exercise
A new study has found that consuming dietary nitrate – the active molecule in beetroot juice – significantly increased muscle force while exercising.
Hospitals without highest stroke care designation may miss them after heart procedure
Hospitals without the highest stroke care designation may be missing strokes that occur after a common heart valve replacement procedure. Investigators found that comprehensive stroke centers reported significantly greater stroke rates after transcatheter aortic valve replacement (TAVR) than hospitals without the designation.
1000 year old record broken: Greenland temperature
Recent high temperatures on the ice sheet in central and northern Greenland lies are unique, when compared to 1000 years of reconstructed climate conditions on the ice sheet.
Childhood trauma linked to civic environmental engagement, green behavior
Experiencing childhood trauma may lead an individual to volunteer, donate money or contact their elected officials about environmental issues later in life, according to recent research published in Scientific Reports.
Valentin Fuster, MD, PhD, Receives Prestigious Award from City of Barcelona, Spain
Mount Sinai Heart President given top honor for his extraordinary scientific achievements
Meat import ban in Africa hurts local population
The EU regularly exports large quantities of poultry meat to West African countries. These exports have been criticized for harming importing countries in West Africa and exacerbating poverty there.
Dogs show things to humans but pigs do not
Researchers at the Eötvös Loránd University (ELTE) Department of Ethology, Budapest investigated if companion pigs and dogs would show their owners the location of a food reward out-of-their reach (but reachable for their owner).
CHOP Researchers Develop Tool that Reduces Errors in Stem Cell Transplant Reporting
Researchers at Children’s Hospital of Philadelphia (CHOP) have developed a custom-built application to automate determination of engraftment, a key outcome after hematopoietic stem cell transplant (HSCT). The application supersedes a tedious manual process and at the same time substantially improves accuracy of reported hematopoietic cell transplant engraftments.
Thomas E. MacGillivray, MD, Elected President of The Society of Thoracic Surgeons
Cardiothoracic surgeon Thomas E. MacGillivray, MD, from MedStar Health, was elected President of The Society of Thoracic Surgeons at STS 2023 during the Society’s Business Meeting.
Team develops strategy to regulate light absorption behaviors of titanium oxo clusters
A research team has improved the solar energy absorption of titanium oxo clusters. Their work demonstrates an effective strategy for regulating the light absorption behaviors of these clusters by importing electron-rich heterometals.
Improving data security for a hybrid society: insights from new study
Society 5.0 envisions a connected society driven by data shared between people and artificial intelligence devices connected via the Internet of Things (IoT).
Grassland ecosystems become more resilient with age
Recent experiments have shown that the loss of species from a plant community can reduce ecosystem functions and services such as productivity, carbon storage and soil health.
Louis B. Sohn: An international legal scholar dedicated to human rights
This story is part of a series, called Georgia Groundbreakers, that celebrates innovative and visionary faculty, students, alumni and leaders throughout the history of the University of Georgia – and their profound, enduring impact on our state, our nation and the world. Louis B. Sohn spent his life promoting international law and peace.
Q&A: How AI can help people be more empathetic about mental health
A team led by researchers at the University of Washington studied how artificial intelligence could help people on the platform TalkLife, where people give each other mental health support. The researchers developed an AI system that suggested changes to participants’ responses to make them more empathetic. The best responses resulted from a collaboration between AI and people.
New soft robots poised to be more agile, controlled
One of the virtues of untethered soft robots is their ability to mechanically adapt to their surroundings and tasks. Now they are poised to become even more agile and controlled.
De Casa en Casa program reducing the burden of cervical cancer by facilitating early diagnosis and access to treatment.
Regular pap tests and HPV testing can prevent and often catch cases of cervical cancer. Each year, approximately 13,000 women are diagnosed with cervical cancer and about 4,000 women die from cervical cancer in the US. Sixty percent of cervical…
Webb Unveils Dark Side of Pre-stellar Ice Chemistry
The discovery of diverse ices in the darkest regions of a cold molecular cloud measured to date has been announced by an international team of astronomers using NASA’s James Webb Space Telescope. This result allows astronomers to examine the simple icy molecules that will be incorporated into future exoplanets, while opening a new window on the origin of more complex molecules that are the first step in the creation of the building blocks of life.
Risky business: Teenage chimps risk it all, like humans
For young chimpanzees, gambling on the possibility of a big payout is an attractive prospect, whereas adult apes are more likely to hedge their bets, a new University of Michigan study shows.
Indiana University Kelley School of Business students establish $4.2 million real estate private equity fund
Students at the Indiana University Kelley School of Business have raised $4.2 million to establish a real estate private equity fund that they and their future peers will manage and use to make investments in existing and future developments. Called Sample Gates Management Inc., it is the largest undergraduate student-managed real estate private equity fund launch, measured by dollars raised, in the country.