English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduAn early-stage study has found that a drug commonly prescribed for diabetes may prove to help treat people with alcohol use disorder. The study, published in Alcohol: Clinical and Experimental Research, found that the diabetes drug metformin reduced alcohol intake in mice.
Tag: Metformin
Diabetes Drug Appears to Fight Lung Cancer — But Only in Overweight or Obese Patients
A widely accessible drug commonly used to control blood glucose levels in diabetic patients has the potential to strengthen the effects of immunotherapy and improve recurrence-free survival in people with lung cancer who are overweight or obese, according to a recently published article in the Journal of the National Cancer Institute.
Experts debate pharmacologic management of a patient with obesity
In a new Annals “Beyond the Guidelines” feature, two internal medicine physicians discuss treatment for a patient with obesity and prediabetes in the context of American Gastroenterological Association (AGA) evidence-based recommendations for the pharmacologic management of obesity in adults.
Continuing metformin during first trimester does not increase risk for major malformations
A study of more than 12,000 pregnant women with type 2 diabetes receiving metformin monotherapy before conception found that compared with switching to insulin monotherapy, continuing metformin and adding insulin in early pregnancy resulted in little to no increased risk for major malformations in the infant.
Paternal use of metformin during sperm production not associated with major birth defects
A study of almost 400,000 live births found that paternal use of metformin monotherapy was not associated with major congenital malformations (MCMs) in newborns.
Timing key for type 2 diabetes drug performance
Researchers from the University of Adelaide could be closer to discovering a better way to use metformin, a common type 2 diabetes medication. Metformin, which has been a cornerstone in diabetes treatment since the 1960s, is typically taken with meals to reduce gastrointestinal side effects but new research is suggesting patients could see improved results if it’s taken before meals.
Study: Metformin can help youth manage weight gain side effect of bipolar medications
A new large-scale study led by researchers at the University of Cincinnati and Northwell Health, New York’s largest health care provider, found the drug metformin can help prevent or reduce weight gain in youth taking medication to treat bipolar disorder.
A Common Diabetes Drug Has a Surprising Side Gig: Muscle Protector
You might not think of diabetes when you think of muscle function. But a common diabetes drug that regulates blood sugar can also prevent muscle atrophy and muscular fibrosis—which can help the elderly bounce back faster from injury or illness.
Cleveland Clinic Researchers Identify Diabetes Drug Metformin as Potential Atrial Fibrillation Treatment in Collaborative Research
Cleveland Clinic researchers have identified a common diabetes medication, metformin, as a possible treatment for atrial fibrillation.
The study, published in Cell Reports Medicine, built on ongoing collaborative Cleveland Clinic research to support further investigation into metformin as a drug repurposing candidate. Researchers used advanced computation and genetic sequencing to determine that metformin’s targets overlap significantly with genes dysregulated in atrial fibrillation.
Spontaneous Mammary Neoplasia, Cannabidiol Exposure, Aryl Hydrocarbon Receptors, and More Featured in July 2021 Toxicological Sciences
Toxicological Sciences delivers the latest toxicology research in the July 2021 issue. The issue features investigations in delivers the latest toxicology research in areas such as exposure to delta-9-tetrahydrocannabinol and cannabidiol, effects of ENDS vapors on amino acid metabolism, and more.
ACSM Annual Meeting Research Highlights for June 3
ACSM’s comprehensive sports medicine and exercise science conference takes place virtually from June 1 to 5 with programming covering the science, practice, public health and policy aspects of sports medicine, exercise science and physical activity.
Could a Common Diabetes Drug Become a New Weapon Against HIV?
UNC School of Medicine scientists found that HIV boosts a key process in human cells to fuel its replication. They also found that the diabetes drug metformin inhibits that process and thereby suppresses HIV replication in these cells in cell lines and animal models.
Combo-Drug Treatment for Type 2 Diabetes Remains Effective After Two Years
Patients whose Type 2 diabetes is not controlled with metformin can benefit long-term from a two-drug combination treatment that also reduces weight.
Diabetes Drug May Protect Breastfed Children from Future Metabolic Disorder
A new study suggests that treating a breastfeeding parent with a common diabetes drug may provide male offspring lifelong protection against diabetes and obesity. The study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism. It was chosen as an APSselect article for May.
Diabetes Drug May Protect Breastfed Sons from Future Metabolic Disorder
Article title: Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner Authors: Zach Carlson, Hannah Hafner, Molly Mulcahy, Kaylie Bullock, Allen Zhu, Dave Bridges, Ernesto Bernal-Mizrachi, Brigid Gregg From the authors: “Future…
Human Gut-in-a-Dish Model Helps Define ‘Leaky Gut,’ and Outline a Pathway to Treatment
UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.
Secret behind diabetes drug’s benefits revealed
Scientists were surprised when they found out that metformin caused the secretion of GDF15, a protein which is known to suppress appetite.
Common Diabetes Medications Tested for Anti-Aging Effects
Two drugs already on the market to treat type two diabetes are being tested in nonhuman primates to see if they can impact the aging process. Researchers dosed marmosets with Metformin and Acarbose and found no adverse side effects