Brain tumors hijack circadian clock to grow

New research from Washington University in St. Louis shows that glioblastoma has an internal clock and syncs its daily rhythms to match — and take advantage of — the rhythms of its host. In this way, brain tumors grow in response to the host’s daily release of steroid hormones like cortisol.

New study links liver-brain communication to daily eating patterns

People who work the nightshift or odd hours and eat at irregular times are more prone to weight gain and diabetes, likely due to eating patterns not timed with natural daylight and when people typically eat. But is it possible to stave off the ill effects of eating at these “unusual” times despite it not being biologically preferable?

Synchronisation between the central circadian clock and the circadian clocks of tissues preserves their functioning and prevents ageing

• Two complementary research articles, published simultaneously in the journals Science and Cell Stem Cell by a team of scientists from the UPF and IRB Barcelona, reveal that central and peripheral circadian clocks coordinate to regulate the daily activity of skin and muscles.
• The coordination between the two clocks (central and peripheral) guarantees 50% of the circadian functions of tissues, including vital processes such as the cell cycle, DNA repair, mitochondrial activity, and metabolism.
• Synchronisation between the central brain clock and peripheral ones prevents premature muscle ageing and improves muscle function, suggesting new strategies to tackle age-related decline through circadian rhythm modulation.

Wintertime blues? Health expert offers tips to combat seasonal affective disorder

Millions are affected by seasonal affective disorder (SAD) every year. The annual pattern of winter depression and melancholy suggests a strong link between your mood and the amount of light you get during the day, says Lina Begdache, assistant professor…

Cooperation between muscle and liver circadian clocks, key to controlling glucose metabolism

Collaborative work by teams at the Department of Medicine and Life Sciences (MELIS) ​​at Pompeu Fabra University (UPF), University of California, Irvine (UCI), and the Institute for Research in Biomedicine (IRB Barcelona) has shown that interplay between circadian clocks in liver and skeletal muscle controls glucose metabolism.

Deaths by suicide increase significantly during the week of a full moon

For centuries, people have suspected a full moon in the sky to cause mysterious changes in people. Now, psychiatrists at Indiana University School of Medicine have found deaths by suicide increase during the full moon.

Dissecting the Circadian Clock in Real Time

Scientists have made progress in understanding the circadian clock, the 24-hour cycle that synchronizes with light-dark exposure, and how it functions. They developed a new way to study how the circadian clock synchronizes in real time, revealing surprises about the clock’s mechanisms.

Protein Deficiency Impairs Muscle Clock, Mitochondrial Function in Muscular Dystrophy

Article title: Dystrophin deficiency disrupts muscle clock expression and mitochondrial quality control in mdx mice Authors: Justin P. Hardee, Marissa K. Caldow, Audrey S.M. Chan, Stuart K. Plenderleith, Jennifer Trieu, Rene Koopman, Gordon S. Lynch From the authors: “These findings suggest that…

Healthy fat impacted by change in diet and circadian clock, study finds

Changing your eating habits or altering your circadian clock can impact healthy fat tissue throughout your lifespan, according to a preclinical study published today in Nature by researchers with The University of Texas Health Science Center at Houston (UTHealth).

The Latest Science on Staying Healthy During Pregnancy

Healthy habits are particularly important during pregnancy. Four new studies being presented at NUTRITION 2021 LIVE ONLINE look at how supplements, eating habits and physical activity can affect various aspects of health during pregnancy.

ACSM Announces 2020 Paper of the Year Selections

The ACSM Publications Committee established an annual Paper of the Year Award in 2020 to recognize one scientific article from each of ACSM’s five journals. Award-winning articles are selected based on impact, research significance, conceptual design and/or technical innovation.

Shift Work Disrupts Kidney Rhythms, Contributes to Kidney and Heart Disease

Article title: Environmental circadian disruption suppresses rhythms in kidney function and accelerates excretion of renal injury markers in urine of male hypertensive rats Authors: Atlantis M. Hill, G. Ryan Crislip, Adam Stowie, Ivory Ellis, Anne Ramsey, Oscar Castanon-Cervantes, Michelle L.…

Protein involved in removing Alzheimer’s buildup linked to circadian rhythm

People with Alzheimer’s disease often have circadian rhythm problems. Researchers at Washington University School of Medicine in St. Louis have discovered a protein that is both regulated by clock genes and involved in clearing away Alzheimer’s protein build-up in the brain. The protein, YKL-40, could provide a new target for Alzheimer’s therapies.

Circadian Clock Regulates Body’s Collagen Production

Researchers featured in the “Homeostasis and adaptation of tendons to exercise” symposium—presented this week virtually at the American Physiological Society (APS) Integrative Physiology of Exercise conference—will discuss how exercise, inactivity and the body’s internal clock drive structural changes to tendons and their supportive tissues.

Biometric Data, Algorithms To Unlock Key Information About Circadian Clock

Researchers at Rensselaer Polytechnic Institute anticipate a future in which a combination of smart wearables and algorithms assess each person’s circadian rhythm and provide personalized feedback as to what light, sleep, and work schedule would be ideal for their particular internal clock. In a foundational step toward that goal, a team of engineers aims to develop reliable mathematical models that can estimate individuals’ circadian rhythms. With the support of a grant from the National Science Foundation (NSF), the team will also develop wearable hardware and software that incorporate various sensors capable of capturing useful biometric information. That data will be used to help build and test the team’s mathematical models.