Lifesaving Trauma Skills Course Quickly and Significantly Sharpens Rarely Used Military Surgeons’ Skills

Military surgeons must maintain a broad set of surgical skills to care for combat-related injuries, but during times of peace, these skills are rarely put to use. However, according to a new JAMA Surgery study, a two-day trauma skills course can significantly improve their proficiency and ensure they are able to continue providing optimal trauma care in combat. The study, “Surgical Skills Training and Assessment of Competency,” was led by researchers at the Uniformed Services University of the Health Sciences (USU) and published Sept. 15.

Surgery, Buprenorphine, and Patients in Recovery from Opioid Use Disorder

With the reintroduction of powerful narcotic opioids to manage acute pain, surgery can be a make-or-break time for patients in recovery from opioid use disorder (OUD). For those using buprenorphine as part of their recovery process, the stress, anxiety and risk can be amplified if, as is often the case, they are directed to stop using the buprenorphine ahead of their surgery.

Brookhaven Lab and Euclid Techlabs to Develop Coated Cathodes for Electron-Ion Collider

The protective coatings are intended to extend the lifetime of the materials for applications in nuclear physics facilities.

The Science Behind the Appeal of Pumpkin Spice

Fall is still days away but at coffee shops and grocery stores, it’s already peak autumn thanks to the arrival of a certain flavor that has come to signal the season’s unofficial start. Everyone knows, it’s pumpkin spice time.

But why?

Johns Hopkins University perception researchers can say a key to understanding why people love pumpkin spice is the smell of it. Those notes of cinnamon, nutmeg and ginger trigger deeply rooted cozy memories of autumn.

Insulin resistance pinned to cell signaling defects that could act as therapy targets

Insulin resistance in the general population seems likely to be caused by a series of cell-specific signaling defects some of which appear to be sex-specific. In addition, only a portion of the defects are shared with those seen in diabetes, pointing towards the existence of novel pathways behind insulin resistance in the general population. According to researchers, this could also be the starting point for new therapeutics to tackle insulin resistance, which is the major driver of type 2 diabetes and metabolic syndrome and is present in 20-30% of the general population in the United States.

Ribociclib added to endocrine therapy extends survival in postmenopausal patients with metastatic breast cancer

A study led by researchers from The University of Texas MD Anderson Cancer Center showed a significant overall survival benefit with ribociclib plus endocrine therapy for postmenopausal patients with hormone receptor-positive (HR+) human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer. This is the first demonstration of a survival advantage with a front-line CDK4/6 inhibitor in postmenopausal patients with
HR+/HER 2- advanced breast cancer.

ESMO: HER2-targeting antibody-drug improves progression-free survival for women with deadly form of advanced breast cancer

A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center has found that treating women with HER2 positive metastatic breast cancer with the HER2-targeting antibody-drug conjugate trastuzumab deruxtecan (T-DXd) significantly prolongs the length of time the disease is controlled and cancer growth is halted when compared to the current standard of care, trastuzumab emtansine (T-DM1).

Antibody-drug conjugate shows impressive activity in patients with non-small cell lung cancer with mutation in HER2 gene

More than half of patients with non-small cell lung cancer (NSCLC) bearing a mutation in the HER2 gene had their tumors stop growing or shrink for an extended time after treatment with a drug that hitches a chemotherapy agent to a highly targeted antibody, an international clinical trial led by investigators at Dana-Farber Cancer Institute has found.

MD Anderson Research Highlights: ESMO 2021 Special Edition

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent studies in basic, translational and clinical cancer research from MD Anderson experts. This special edition features oral presentations by MD Anderson researchers at the virtual European Society for Medical Oncology (ESMO) Congress 2021 on novel therapeutic approaches, including cell therapy for solid tumors, antibody drug conjugates targeting TROP2 and neoadjuvant pembrolizumab for advanced solid tumors with mismatch repair deficiencies.

Now We’re Cooking with Lasers

Imagine having your own digital personal chef; ready to cook whatever you want, tailoring the shape, texture, and flavor just for you–all at the push of a button. Columbia engineers have been working on doing just that, using lasers for cooking and 3D printing technology for assembling foods. In their new study they discovered that laser-cooked meat shrinks 50% less, retains double the moisture content, and shows similar flavor development to conventionally cooked meat.

NREF and AANS/CNS Tumor Section Announce StacheStrong and NREF Research Grant Recipients

The Neurosurgery Research and Education Foundation (NREF) and the American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) Section on Tumors are pleased to announce Jacob Young, MD, and Daniel Green Eichberg, MD, as the recipients of the StacheStrong and NREF Research Grants on behalf of the AANS/CNS Section on Tumors. These grants were funded by the NREF through a partnership with StacheStrong, a 501(c)3 not-for-profit charity focused on raising funds and awareness for brain cancer research.

Bowen Law School Receives $1 million from Walmart to Fund Court Observation Project

The UA Little Rock William H. Bowen School of Law has received a $1 million grant from Walmart, Inc. The grant will fund a Court Observation Project through Bowen’s new Center for Racial Justice and Criminal Justice Reform. The project will introduce a state-wide court observation initiative that will create and share a transparent body of reliable data and research about Arkansas’s criminal justice system that is otherwise unavailable in the state.

COVID-19 Pandemic Hastens Cleveland Clinic’s Unified Well-Being Strategy

The COVID-19 pandemic has been a catalyst for shaping a new future in healthcare. At the Cleveland Clinic, top priorities throughout the pandemic have been to support caregivers professionally and personally and to help them be their best for themselves, their fellow caregivers, patients, organizations, and communities.

Common anti-seizure medication associated with elevated fracture risk in kids with epilepsy

A study found that one of the two most commonly prescribed anti-seizure medications is associated with a higher risk of fracture for children and teens with epilepsy. This is significant for this population as it comes during a critical period of bone development, a time during which several features coalesce to develop bone strength that peaks in adulthood.

5 Henry Ford Hospitals Earn Top Quality Recognition for Stroke Care Excellence

All of Henry Ford Health System’s five hospitals that are equipped to treat stroke earned Gold Plus and Honor Roll status for stroke care excellence from the American Heart Association and American Stroke Association.

University of Kentucky Researcher a Force in the Fight Against Lyme Disease

At a time when incidence of Lyme disease is rising across the U.S., a study led by University of Kentucky College of Medicine researcher Brian Stevenson, Ph.D., may provide a significant impact in the fight against the disease. A new study will build upon Stevenson’s three decades of research aimed at understanding Borrelia burgdorferi, the bacteria that causes Lyme disease.