Cancer Risk After Radioactive Iodine Treatment for Hyperthyroidism


JAMA Network Open


Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.


What The Study Did: The results of this systematic review and meta-analysis that included 12 observational studies and nearly 500,000 participants suggest that radiation-induced cancer risks following radioactive iodine therapy for hyperthyroidism are small, and in observational studies, may only be detectable at higher dose levels.

Authors: Won Jin Lee, M.D., Ph.D., of the Korea University College of Medicine in Seoul, is the corresponding author.



Editor’s Note: The article includes funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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