Superpowered ‘superantigens’ identified in University of North Dakota anti-cancer research

A team of researchers at UND’s School of Medicine & Health Sciences might just have revolutionized the treatment of solid tumor cancers.

As reported in the prestigious Journal for Immunotherapy of Cancer, a team led by Department of Biomedical Sciences professors David S. Bradley, Ph.D., and David S. Terman, M.D., identified two new members of the “superantigen” family that, when combined with a common “helper” molecule, showed significantly higher cure rates in and long-term survival of animals with solid tumors compared to other immunotherapeutic agents now deployed clinically.

Stable Nickel-64 Nuclei Take Three Distinct Shapes

Scientists have identified three distinct shapes in stable nickel-64 that appear as energy is added to the nucleus. The nucleus in the lowest-energy state is spherical, then takes elongated (prolate) and flattened (oblate) shapes as the protons and neutrons surrounding the nucleus gain energy. This demonstrates profound changes in the way protons and neutrons can arrange themselves.

Keeping it Cool while Maintaining Core Performance

One of the great challenges in fusion tokamaks is how to keep the core of a plasma hot enough that fusion can occur while maintaining a temperature at the edge of the plasma low enough that it doesn’t melt the tokamak’s walls. This requires dissipating the heat and particles flowing towards the wall without reducing the performance of the core. Researchers recently developed a pathway to addressing this core-edge integration challenge.

Simulation Helps Refine Pediatric Care Guidelines For COVID-19

DALLAS – Jan. 28, 2021 – Simulation can be a viable way to quickly evaluate and refine new medical guidelines and educate hospital staff in new procedures, a recent study from UT Southwestern’s Department of Pediatrics shows. The findings, published recently in the journal Pediatric Quality and Safety and originally shaped around new COVID-19-related pediatric resuscitation procedures at UTSW and Children’s Health, could eventually be used to help implement other types of guidelines at medical centers nationwide.

Vice Presidential Vogue: Kamala Harris and White House Fashion

As Kamala Harris stood beside newly sworn-in President Joe Biden last week, all eyes were on her as she made history as the nation’s first female vice president.  But, much like other prominent women who have walked the halls of the White House before her, cultural experts expect that there will be  just as much focus on her fashion statements as on her political ones — and the scrutiny may be intensified as the first woman and person of color in the VP position takes on stereotypes surrounding Eurocentric standards of beauty.

National laboratories’ magnet designers look to the future of light sources with new prototype

After more than 15 years of work, scientists at three DOE national laboratories have succeeded in creating and testing an advanced, more powerful superconducting magnet made of niobium and tin for use in the next generation of light sources.

Biochemistry researcher receives National Science Foundation Award

The five-year, $680,500 NSF Faculty Early Career Development Program award will be utilized to gain a better understanding of how improper DNA replication and compaction can cause changes in gene expression in offspring while creating a comprehensive learning environment for aspiring high school-aged and undergraduate scientists who will have significant roles in the research.

AERA and Spencer Foundation Release Focus Group Findings on the Impact of the COVID-19 Pandemic on Early Career Scholars and Doctoral Students

The American Educational Research Association (AERA) and the Spencer Foundation have released a report, Voices from the Field: The Impact of COVID-19 on Early Career Scholars and Doctoral Students, that shares findings from focus groups conducted in spring 2020. The report, available on the AERA and Spencer websites, is part of an ongoing initiative by the two organizations to assess the pressing needs facing scholars and doctoral students during the pandemic and ways to address these needs.

Resultados de estudio ofrecen más exactitud para calcular el riesgo de cáncer de mama en mujeres sin antecedentes familiares

Un nuevo estudio llevado a cabo en varias instituciones y dirigido por el Dr. Fergus Couch, patólogo en Mayo Clinic, aporta un cálculo más exacto sobre el riesgo de cáncer de mama en las mujeres estadounidenses con mutaciones heredadas en los genes de predisposición a ese tipo de cáncer.

Validation of Novel Prognostic Index May Better Inform Burkitt Lymphoma Treatment

Rutgers Cancer Institute of New Jersey together with RWJBarnabas Health, today announced the publication of research that has identified and validated the novel Burkitt Lymphoma International Prognostic Index (BL-IPI) in patients with this rare, high-grade B-cell lymphoma that is often studied in trials with small sample sizes. This research has been published in the January 2021 online issue of Journal of Clinical Oncology.

Chemists Settle Battery Debate, Propel Research Forward

UPTON, NY—A team of researchers led by chemists at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory has identified new details of the reaction mechanism that takes place in batteries with lithium metal anodes. The findings, published today in Nature Nanotechnology, are a major step towards developing smaller, lighter, and less expensive batteries for electric vehicles.

University Hospitals Richmond Medical Center Physician Brings New Wound Healing Technology to Ohio

University Hospitals (UH) Richmond Medical Center is the first clinical setting in Ohio to utilize a special technology that sends acoustic sound waves to wounds to jump start the healing process. Windy Cole, DPM, Certified Wound Specialist Physician at the Center for Wound Care at UH Richmond Medical Center, is leading the use of the novel device in the state through research and case studies.

The dermaPACE® System from SANUWAVE, is an FDA approved device indicated for treatment of diabetic foot ulcers. The device delivers acoustic shock waves to tissues, helping to jump start wound healing through new blood vessel formation.

Researchers use patients’ cells to test gene therapy for rare eye disease

Scientists at the National Eye Institute (NEI) have developed a promising gene therapy strategy for a rare disease that causes severe vision loss in childhood. A form of Leber congenital amaurosis, the disease is caused by autosomal-dominant mutations in the CRX gene, which are challenging to treat with gene therapy.

X-Ray Tomography Lets Researchers Watch Solid-State Batteries Charge, Discharge

Using X-ray tomography, a research team has observed the internal evolution of the materials inside solid-state lithium batteries as they were charged and discharged. Detailed three-dimensional information from the research could help improve the reliability and performance of the batteries, which use solid materials to replace the flammable liquid electrolytes in existing lithium-ion batteries.

Livestock workers face high MRSA risk

For Michigan State University’s Felicia Wu, the surprise isn’t that people who work with livestock are at higher risk of picking up antibiotic-resistant bacteria, but instead how much higher their risk levels are.

“This is a bit of a wakeup call,” said Wu, John. A Hannah Distinguished Professor in the Departments of Food Science and Human Nutrition and Agricultural, Food and Resource Economics. “I don’t think there was much awareness that swine workers are at such high risk, for example. Or that large animal vets are also at extremely high risk.”