immune checkpoint | sciencenewsnet.in

How a little-known glycoprotein blocks a cancer cell’s immune response

January 28, 2021 sarah Jonas Cancer, immune checkpoint, Immunotherapy

Researchers uncovered how stanniocalcin-1, or STC1, works inside a tumor cell to block a cellular “eat-me” signal that typically triggers the immune system to produce T cells to fight the tumor. The findings provide a potential target to improve immune responses to cancer.

Research Results

Artificial Intelligence Program Can Pick Best Candidates for Skin Cancer Treatment

November 18, 2020 sarah Jonas Artifical Intelligence, immune checkpoint, Immunotherapy, machine learning algorithm

Experts trained a computer to tell which skin cancer patients may benefit from drugs that keep tumors from shutting down the immune system’s attack on them, a new study finds.

Research Results

Researchers identify mechanism underlying cancer cells’ immune evasion

August 27, 2020 sarah Jonas Cancer, Glioblastoma, immune checkpoint, Immunotherapy, PD-1, PD-L1

Researchers in China have discovered how brain cancer cells increase production of a key protein that allows them to evade the body’s immune system. The study, which will be published August 27 in the Journal of Experimental Medicine (JEM), suggests that targeting this cellular pathway could help treat the deadly brain cancer glioblastoma, as well as other cancers that are resistant to current forms of immunotherapy.