Binghamton University researcher to aid innovative Mayo Clinic project to treat inflammatory diseases

Binghamton University, State University of New York will play a key role in a federal grant of up to $42.8 million to develop an implantable device that acts as a living pharmacy to treat inflammatory diseases. Mayo Clinic is the prime site for this groundbreaking research, and researchers at Binghamton will assist with bioengineering the transplanted cells.

New Computational Method Links One Mammal’s Striking Longevity and Resistance to Cancer With ‘Dark Genome’

The Roswell Park team has developed a new method to measure mutation loads across species, revealing the role of the “dark genome” — ancient, virus-like genes that affect cellular function. The findings support further exploration of antiviral drugs as potential tools to target the dark genome in controlling cancer.

Existing standard chemoradiation superior to deintensification approaches for HPV-related oropharyngeal cancer

Researchers looking to de-intensify radiation treatments for people with early-stage, HPV-associated oropharyngeal cancer to prevent long-term side effects halted a large, randomized phase II/III trial after patients in the control arm reached a record high, two-year progression-free survival rate of 98%.

Down on Vitamin D? It could be the cause of chronic inflammation

World-first genetic research from the University of South Australia shows a direct link between low levels of vitamin D and high levels of inflammation, providing an important biomarker to identify people at higher risk of or severity of chronic illnesses with an inflammatory component.

Cedars-Sinai Investigators ID Gene Critical to Human Immune Response

Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body’s white blood cells to go on the attack against a foreign presence.

Study: Obesity raises the risk of gum disease by inflating growth of bone-destroying cells

Chronic inflammation caused by obesity may trigger the development of cells that break down bone tissue, including the bone that holds teeth in place, according to new University at Buffalo research that sought to improve understanding of the connection between obesity and gum disease.

Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Wednesday.

Negative side effects of opioids could be coming from users’ own immune systems (video)

Opioid users can develop chronic inflammation and heightened pain sensitivity. These side effects might stem from the body’s own immune system, which can make antibodies against the drugs. The researchers will present their results at the American Chemical Society Fall 2020 Virtual Meeting & Expo.