New technique allows scientists to measure mitochondrial respiration in frozen tissue

UCLA scientists have developed a method for restoring oxygen-consumption activity to previously frozen mitochondria samples. By speeding up research, investigators hope to accelerate the diagnosis of people living with mitochondrial diseases and secondary disorders in which mitochondria play a key role, including diseases related to aging, metabolism and the heart.

Lancet Neurology publishes results of AFFiRiS’ Phase 1 trial with PD01A in Parkinson’s

Vienna, Austria, June 18, 2020 – AFFiRiS AG, a clinical-stage biotechnology company developing novel disease-modifying specific active immunotherapies (SAITs), today announced that detailed results of the phase 1 clinical program with its lead candidate PD01 in early Parkinson’s disease (PD)…

Solving a Parkinson’s disease puzzle through protein design

Dopamine is a neurotransmitter involved in everything from higher cognitive functions to motor control, motivation, arousal, reinforcement, and sexual gratification, the receptors it acts on have been a longstanding target for treating disorders like Parkinson’s disease, which is caused by…

Solving a Parkinson’s disease puzzle through protein design

Dopamine is a neurotransmitter involved in everything from higher cognitive functions to motor control, motivation, arousal, reinforcement, and sexual gratification, the receptors it acts on have been a longstanding target for treating disorders like Parkinson’s disease, which is caused by…

Open Wearables Initiative (OWEAR) releases open source software and datasets database for wearable and connected health technologies

Shimmer Research, a global leader in wearable technology for research applications, today announced that the Open Wearables Initiative (OWEAR) has uploaded its open source software and datasets database for wearable sensors and other connected health technologies to its website at…

Open Wearables Initiative (OWEAR) releases open source software and datasets database for wearable and connected health technologies

Shimmer Research, a global leader in wearable technology for research applications, today announced that the Open Wearables Initiative (OWEAR) has uploaded its open source software and datasets database for wearable sensors and other connected health technologies to its website at…

Molecular pair offers potential for Parkinson’s treatment, finds NTU Singapore-Harvard study

A promising molecular pair has offered hope that could lead to the development of a new treatment to slow down Parkinson’s disease, a study by Nanyang Technological University, Singapore (NTU Singapore) and Harvard University has found. Parkinson’s disease is the…

Molecular pair offers potential for Parkinson’s treatment, finds NTU Singapore-Harvard study

A promising molecular pair has offered hope that could lead to the development of a new treatment to slow down Parkinson’s disease, a study by Nanyang Technological University, Singapore (NTU Singapore) and Harvard University has found. Parkinson’s disease is the…

Cutting edge two-photon microscopy system breaks new grounds in retinal imaging

Retina is the only part of the central nervous system (CNS) that can be visualized noninvasively with optical imaging approaches. Direct retinal imaging plays an important role not only in understanding diseased eye and ocular therapeutic discovery, but also study…

Cutting edge two-photon microscopy system breaks new grounds in retinal imaging

Retina is the only part of the central nervous system (CNS) that can be visualized noninvasively with optical imaging approaches. Direct retinal imaging plays an important role not only in understanding diseased eye and ocular therapeutic discovery, but also study…

Significant differences exist among neurons expressing dopamine receptors

An international collaboration, which included the involvement of the research team from the Institut de Neurociències of the UAB (INC-UAB), has shown that neurons expressing dopamine D2 receptors have different molecular features and functions, depending on their anatomical localization within…

Significant differences exist among neurons expressing dopamine receptors

An international collaboration, which included the involvement of the research team from the Institut de Neurociències of the UAB (INC-UAB), has shown that neurons expressing dopamine D2 receptors have different molecular features and functions, depending on their anatomical localization within…

Scientists show MRI predicts the efficacy of a stem cell therapy for brain injury

Scientists at Sanford Burnham Prebys Medical Discovery Institute and Loma Linda University Health have demonstrated the promise of applying magnetic resonance imaging (MRI) to predict the efficacy of using human neural stem cells to treat a brain injury—a first-ever “biomarker” for regenerative medicine that could help personalize stem cell treatments for neurological disorders and improve efficacy. The study was published in Cell Reports.

Predictive models could provide more accurate detection of early-stage Parkinson’s disease

TORONTO, May 11, 2020 – How is your sense of smell? Do you find yourself frequently dozing off during the day or thrashing about during dreams? Often, early stage Parkinson’s disease does not present with typical motor disturbance symptoms, making diagnosis…