news, journals and articles from all over the world.
A new study led by Prof. Omry Koren and graduate student Atara Uzan-Yuzari from the Azrieli Faculty of Medicine at Bar-Ilan University has unveiled significant evidence connecting the gut microbiome to aggressive behavior in mice.
Published in the journal Brain, Behavior, and Immunity, the research explores how disruptions in the microbiome, particularly due to antibiotic use in early life, can lead to increased aggression.
Article title: SGLT2 inhibition leads to a restoration of hepatic and circulating metabolites involved in the folate cycle and pyrimidine biosynthesis Authors: Ileana Mendez Espinoza, Elijah N. D. Choos, Carolyn M. Ecelbarger, Blythe D. Shepard From the authors: “Here, we…
Using a 26-year-old common garden forest, a multi-institutional team of researchers collected fine root samples from four temperate tree species (three deciduous and one coniferous) that varied in their morphology.
New insights into the metabolism of autism from researchers at UC San Diego could help inform early detection and prevention strategies for the disorder.
PNNL contributes to a nationwide research consortium investigating the molecular mechanisms triggered by endurance training.
Researchers from University of California San Diego have developed a new search tool to that can match microbes to the metabolites they produce with no prior knowledge, an innovation that could transform our understanding of both human health and the environment.
UC San Diego researchers describe a new method to identify all of the unidentified molecules derived from food, providing a direct way to link molecules in diet to health outcomes.
Article title: Metabolomic signatures of low- and high-adiposity neonates differ based on maternal BMI Authors: Begum Aydogan Mathyk, Brian D. Piccolo, Fernanda Alvarado, Kartik Shankar, Perrie O’Tierney-Ginn From the authors: “Using untargeted metabolomics in 100 newborns, we found that cord…
A new platform housing data from over 100 apple varieties could shave years off of the breeding process and enable data-driven assessments of how to boost the health benefits of America’s favorite fruit.
Until now, systemic biomarkers to measure exercise effects on brain function and that link to relevant metabolic responses were lacking. A study shows a memory biomarker, myokine Cathepsin B (CTSB), increased in older adults following a 26-week structured aerobic exercise training. The positive association between CTSB and cognition, and the substantial modulation of lipid metabolites implicated in dementia, support the beneficial effects of exercise training on brain function and brain health in asymptomatic individuals at risk for Alzheimer’s.
A new study with zebrafish shows that a deadly form of skin cancer — melanoma — alters the metabolism of healthy tissues elsewhere in the body. The research from Washington University in St. Louis suggests that these other tissues could potentially be targeted to help treat cancer.“Tumors rely on a constant supply of nutrients to grow.
Precision medicine is a rapidly growing approach to health care that focuses on finding treatments and interventions that work for people based on their genetic makeup, rather than their symptoms.
Zeeshan Ahmed, director of the new Ahmed Lab at Rutgers Institute for Health, Health Care Policy and Aging Research, discusses the future of precision medicine, what needs to be done to successfully analyze the data necessary to develop individualized treatments and the role genetics play during the COVID-19 pandemic.
For the first time, researchers use a metabolomics approach to find more detailed information about how tobacco use and smoking practices changed after colonization in North America.
Scientists have deployed artificial intelligence to identify more of the billions of metabolites that are currently unknown. The small molecules underlie and inform every aspect of our lives, including energy production, the fate of the planet, and our health. “Beast Mode” helps explain how they did it.
The April 2020 issue of the Society of Toxicology’s official journal, Toxicological Sciences, features leading research in toxicology, including several manuscripts covering emerging technologies, methods, and models.
New research finds that exercise causes changes to some of the body’s metabolites—small molecules the body produces during metabolism—and also triggers change in blood levels of unique “foreign” molecules not thought to stem from our own metabolism. These changes to the global metabolome—the entire group of metabolites found throughout the body in the blood, tissues or urine—may help scientists better understand the body’s response to exercise.
Noninvasive measurement may provide alternative to diagnostic kidney biopsy Charlottesville, Va. (June 24, 2019)—Metabolomics, the study of small molecules the body produces during metabolism (metabolites) may be a future key to identifying diabetes-related kidney disease. The finding will be presented…
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