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UrduArticle title: Decreased skeletal muscle intramyocellular lipid droplet-mitochondrial contact contributes to myosteatosis in cancer cachexia Authors: Thomas D. Cardaci, Brandon N. VanderVeen, Alexander R. Huss, Brooke M. Bullard, Kandy T. Velazquez, Norma Frizzell, James A. Carson, Robert L. Price, E.…
Tag: high-fat diet
Intake Reduction and Pre-surgery Body Weight Explain Efficacy of Weight Loss Surgery
A new study finds that pre-surgery weight plays a role in how much weight loss occurs after gastric bypass. The study is published ahead of print in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology and has been chosen as an APSselect article for June.
Study Reveals How Obesity Could Accelerate Aging in the Brain
A new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood to the brain. The work is being presented this week at the American Physiology Summit, the flagship annual meeting of the American Physiological Society.
Fatty food before surgery may impair memory in old, young adults
Eating fatty food in the days leading up to surgery may prompt a heightened inflammatory response in the brain that interferes for weeks with memory-related cognitive function in older adults – and, new research in animals suggests, even in young adults.
Saturated fat may interfere with creating memories in aged brain
New research hints at a few ways fatty foods affect cells in the brain, a finding that could help explain the link between a high-fat diet and impaired memory – especially as we age.
High fat diet activates early inflammation in mouse brains, supports link to neurologic disease
Researchers at Michigan Medicine have discovered that a high-fat diet promotes an early inflammatory response in the brains of mice through an immune pathway linked to diabetes and neurologic diseases, suggesting a possible bridge between metabolic dysfunction and cognitive impairment.
Vitamin B5 May Help Weight Loss by Turning on Brown Fat
Pantothenate acid, also known as vitamin B5, stimulated the production of brown fat in both cell cultures and mice, a new study finds. “[B5] has therapeutic potential for treating obesity and type II diabetes,” researchers conclude. The study was chosen as an APSselect article for July.
High-fat Diet Induces High Blood Pressure in Rat Kidneys
A high-fat diet after 16 weeks induced hypertension in rats, according to researchers from Henry Ford Health and Wayne State University in Detroit.
Study: Obesity raises the risk of gum disease by inflating growth of bone-destroying cells
Chronic inflammation caused by obesity may trigger the development of cells that break down bone tissue, including the bone that holds teeth in place, according to new University at Buffalo research that sought to improve understanding of the connection between obesity and gum disease.
How high-fat diets allow cancer cells to go unnoticed
A high-fat diet increases the incidence of colorectal cancer. Cold Spring Harbor Laboratory Fellow Semir Beyaz and collaborators from Harvard Medical School and Massachusetts Institute of Technology have discovered that in mice, fat disrupts the relationship between intestinal cells and the immune cells that patrol them looking for emerging tumors.
Food for thought: The ketogenic diet as epilepsy treatment
Treating epilepsy with diet is not a new concept, but it’s gained popularity and credibility in the past 25 years.
High-fat Diet in Childhood May Affect Sperm Later in Life
New research in mice suggests that a high-fat diet early in life may impair male fertility in adulthood. The first-of-its-kind study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism.
High-fat Diet and Genetics Lead to Anxiety and Depression in Rats
New research in a genetically diverse rat strain finds high-fat diet and genetics together increase anxiety and depression-like behavior in addition to negatively affecting metabolic health. The study is published ahead of print in Physiological Genomics.
Study Suggests Low-carbohydrate, High-fat Diet Protects against Obesity
Article title: Dietary carbohydrates modulate metabolic and β-cell adaptation to high-fat diet-induced obesity Authors: Tracy K. Her, William S. Lagakos, Matthew R. Brown, Nathan K. LeBrasseur, Kuntol Rakshit, Aleksey V. Matveyenko From the authors: “These studies support the hypothesis that low carbohydrate/high…
Lack of Sodium Channel Component Protects against Diet-induced Artery Stiffening
Article title: Western diet induces renal artery endothelial stiffening that is dependent on the epithelial Na+ channel Authors: Yuxin Xiong, Annayya R. Aroor, Francisco I. Ramirez-Perez, Guanghong Jia, Javad Habibi, Camila Manrique-Acevedo, Guido Lastra, Donqqing Chen, Vincent G. DeMarco, Luis A.…
Loss of Enzyme in Fat Tissue Leads to Improved Insulin Sensitivity in Liver
Article title: DPP4 deletion in adipose tissue improves hepatic insulin sensitivity in diet-induced obesity Authors: Tania Romacho, Henrike Sell, Ira Indrakusuma, Diana Roehrborn, Tamara R. Castañeda, Tomas Jelenik, Daniel Markgraf, Sonja Hartwig, Jürgen Weiß, Hadi Al-Hasani, Michael Roden, Jürgen Eckel…