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UrduA study led by UC Davis distinguished professor Andreas Bäumler uncovered how Salmonella, a major cause of food poisoning, can invade the gut despite the presence of protective bacteria.
Tag: Bacterial Infections
£2 million grant to research reducing AIDS-related deaths caused by bacterial and fungal infections
Professor Nelesh Govender was awarded one of 7 prestigious 5-year UK National Institute for Health and Care Research (NIHR) Global Research Professorships.
Machine learning to battle COVID-19 bacterial co-infection
University of Queensland researchers have used machine learning to help predict the risk of secondary bacterial infections in hospitalised COVID-19 patients.
Resistant bacteria can remain in the body for years
Fighting disease-causing bacteria becomes more difficult when antibiotics stop working.
New and highly infectious E. coli strain resistant to powerful antibiotics
A new type of E. coli that is both highly infectious and resistant to some antibiotics has been discovered.
Engineering viruses to kill deadly pathogens
Northwestern University researchers have successfully coaxed a deadly pathogen to destroy itself from the inside out.
Neutralizing antibodies that target resistant bacteria
Antibiotic-resistant bacteria pose a major challenge to healthcare systems worldwide. Due to numerous resistance mechanisms, infections with the pathogen Pseudomonas aeruginosa are particularly feared. Researchers at the German Center for Infection Research (DZIF), the University Hospital Cologne, the Helmholtz Centre for Infection Research in Braunschweig and the University Medical Center Hamburg-Eppendorf have now discovered antibodies that could lead to a highly potent treatment option of acute and chronic infections with P. aeruginosa. The study was published in the prestigious scientific journal Cell.
HMS Researcher to Lead $104 Million Federal Project Tackling Antibiotic Resistance
Multi-institutional effort aims to develop technology to transform diagnosis, treatment of bacterial infections
More people develop sepsis than we thought — but more survive
Sepsis, also colloquially referred to as blood poisoning, is a serious condition. Just over 3,000 people die with a diagnosis of sepsis in Norwegian hospitals each year.
Sugars in breastmilk could help treat infections, prevent preterm births
Certain sugars naturally found in breastmilk could help prevent infections before a baby arrives. Researchers reporting in ACS Central Science have found that these sugars can stop a common prenatal infection in human tissues and pregnant mice.
Menstrual cups can help prevent infection, improve vaginal health
Kenyan teenage girls who were given menstrual cups were less likely to acquire certain kinds of vaginal infections and were more likely to have a healthy vaginal microbiome, found a study by University of Illinois Chicago researchers.
CHOP Researchers Reveal How NSAIDs Worsen C. difficile Infections
Why do nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate gastrointestinal infections by Clostridioides difficile, the leading cause of antibiotic-associated diarrhea worldwide? In a new paper published in Science Advances, researchers at Children’s Hospital of Philadelphia (CHOP) have begun to answer that question, showing that NSAIDs disrupt the mitochondria of cells lining the colon, sensitizing them to damage by pathogenic toxins.
Historical medicine suggests a new way to use modern treatments
The mixture of honey and vinegar, also known as oxymel, has been used as a medical treatment throughout history and now scientists have established that this combination could have modern applications in the treatment of wounds. New research is the first comprehensive exploration of how the mixture could be applied to modern medicine and improve treatments for infections.
Vaginal suppository containing lactobacilli can prevent recurrent cystitis in women
A team of scientists from Okayama University, Japan demonstrated the relationship between vaginal microbiota and RC by comparing the vaginal microbiota of postmenopausal women with and without cystitis.
Previously unknown antibiotic resistance widespread among bacteria
Genes that make bacteria resistant to antibiotics are much more widespread in our environment than was previously realised.
New Class of Antibiotics to Fight Resistant Bacteria
Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria’s metabolism.
New shape-shifting antibiotics could fight deadly infections
In the United States alone, drug-resistant bacteria and fungi infect almost 3 million people per year and kill about 35,000.
A healthy microbiome may prevent deadly infections in critically ill people
Twenty to 50 per cent of all critically ill patients contract potentially deadly infections during their stay in the intensive care unit or in hospital after being in the ICU – markedly increasing the risk of death.
New live bacterial product for stubborn superbug improves quality of life
Kevin Garey, professor of pharmacy practice and translational research at the University of Houston College of Pharmacy is reporting the first well-controlled study to demonstrate that a microbiome therapeutic, SER-109, is associated with significant quality of life improvement in patients with the debilitating recurrent infection and disease caused by Clostridium difficile (or C. diff).
Mapping E. coli to overcome antibiotic resistance
Antibiotic resistance, when infection-causing bacteria evolve so they are no longer affected by typical antibiotics, is a global concern.
Study shows superbugs in the environment rarely transfer over to humans: Hospitals are more risky than farms
An international team of scientists investigating transmission of a deadly drug resistant bacteria that rivals MRSA, has found that whilst the bugs are found in livestock, pets and the wider environment, they are rarely transmitted to humans through this route.
Tiny swimming robots treat deadly pneumonia in mice
UC San Diego engineers have developed microscopic robots, called microrobots, that can swim around in the lungs, deliver medication and be used to clear up life-threatening cases of bacterial pneumonia. In mice, the microrobots safely eliminated pneumonia-causing bacteria in the lungs and resulted in 100% survival. By contrast, untreated mice all died within three days after infection.
New drug candidate fights off more than 300 drug-resistant bacteria
Urinary tract infections are common, yet can be tough to treat as the bacteria that cause them become resistant to many antibiotics. In ACS Central Science, researchers report a new molecule that inhibits drug-resistant bacteria in lab experiments, as well as in mice with pneumonia and UTIs.
Exploring arcobacter risk to the food industry and human health
The increase in the discovery of Arcobacter in food samples of all types raises public health concerns, as very little is known as yet about the pathogenic potential of Arcobacter species, and the few studies that have been carried out show a large number of host species and transmission routes.
Children’s Hospital of Philadelphia Researchers Identify Approach for Potential Nontypeable Haemophilus Influenzae Vaccine
Scientists at Children’s Hospital of Philadelphia (CHOP) have identified two proteins that could be used for a potential vaccine against nontypeable Haemophilus influenzae (NTHi). Working in a mouse model, the investigators found that administering two bacterial adhesive proteins that play a key role in helping the bacteria to latch on to respiratory cells and initiate respiratory tract infection stimulated protective immunity against diverse NTHi strains, highlighting the vaccine potential.
Using nanobodies to block a tick-borne bacterial infection
Tiny molecules called nanobodies, which can be designed to mimic antibody structures and functions, may be the key to blocking a tick-borne bacterial infection that remains out of reach of almost all antibiotics, new research suggests.
Escape Artists: How Vibrio Bacteria Break Out of Cells
DALLAS – Aug. 18, 2020 – As soon as the foodborne pathogen Vibrio parahaemolyticus infects a human intestinal cell, the bacteria are already planning their escape. After all, once it is in and multiplies, the bacterium must find a way out to infect new cells.
A wound dressing that kills bacteria
In order to combat bacterial wound infections, Empa researchers have developed cellulose membranes equipped with antimicrobial peptides. Initial results show: The skin-friendly membranes made of plant-based materials kill bacteria very efficiently.
Targeting the cancer microenvironment
The recognition of bacterial infections or foreign substances is mediated and controlled by the human immune system. This innate and adaptive immune system comprises the most important metabolic and cellulare processes to fight against infections and other diseases.
Color-changing bandages sense and treat bacterial infections
Researchers reporting in ACS Central Science have developed color-changing bandages that can sense drug-resistant and drug-sensitive bacteria in wounds and treat them accordingly.